Results 161 to 170 of about 98,417 (285)

Retrospective Study of Hepatotoxicity of Gemcitabine (Gemzar®)as First-line Chemotherapy in Non-Small Cell Lung Cancer

open access: yes, 2007
在非小細胞肺癌(Non-small cell lung cancer)之治療藥物中,gemcitabine(Gemzar®)被使用作為後期(advanced)患者之標準療法用藥之一,和其他細胞毒性(cytotoxic)藥物比較起來,其副作用通常較為輕微。但肝毒性(hepatotoxicity)之發生並不少見(約20~50%),表現多為短暫、無症狀且很快恢復之肝酵素升高,很少會持續惡化;除此之外,近年來,越來越多之案例報告顯示gemcitabine有可能造成嚴重肝毒性,如肝臟靜脈阻塞疾病 ...
Wu, Ying-Hui, 吳盈慧
core  

Optimal Stenting Strategy During Chemotherapy: Impact of Time to First Reintervention on Survival in Malignant Hilar Biliary Obstruction

open access: yesDEN Open, Volume 7, Issue 1, April 2027.
ABSTRACT Objectives Advances in chemotherapy have increased survival in biliary tract cancer patients, and reports of the effectiveness of neoadjuvant therapy are emerging. Accordingly, developing optimal drainage strategies under chemotherapy is important.
Katsuhiko Sato   +8 more
wiley   +1 more source

Spatiotemporally programmed nanomedicine engineering to resolve conflicting immunosignals in triple-negative breast cancer. [PDF]

open access: yesSignal Transduct Target Ther
Guo X   +22 more
europepmc   +1 more source

Characteristics and Outcomes of Patients With Dedifferentiated Liposarcoma in a US Community Setting. [PDF]

open access: yesCancer Med
US community oncology patients with dedifferentiated liposarcoma have heterogeneous profiles, treatments, and outcomes. The poor survival rates in this population suggest an unmet need for better therapeutics. ABSTRACT Introduction Clinical characteristics and outcomes of patients treated for dedifferentiated liposarcoma (DDLPS) at community oncology ...
Butrynski JE   +10 more
europepmc   +2 more sources

Small‐Bowel Impaction Caused by Mechanical Interlocking Between Duodenal Metal and Biliary Plastic Stents

open access: yesDEN Open, Volume 7, Issue 1, April 2027.
ABSTRACT Duodenal self‐expandable metal stents (SEMS) are widely used to treat malignant gastric outlet obstruction (GOO). However, stent migration is a well‐known complication. We report a rare case of small‐bowel impaction caused by the migration of a duodenal SEMS with a biliary plastic stent (PS).
Shinsuke Otagiri   +9 more
wiley   +1 more source

Comparison of gemcitabine monotherapy with gemcitabine and cisplatin combination in metastatic pancreatic cancer: a retrospective analysis

open access: yes, 2018
Purpose: Gemcitabine is among the standard first-line agents for the treatment of metastatic pancreatic cancer. However, as the median survival with gemcitabine monotherapy is 6 months, different combinations are being studied for better, prolonged ...
Engins, Huseyin   +15 more
core  

Systemic anti‐cancer therapy associated with the occurrence of peripheral neurotoxicity and, specifically, peripheral neuropathy

open access: yesInternational Journal of Cancer, Volume 159, Issue 2, Page 460-466, 15 July 2026.
What's new? While the effectiveness of systemic anticancer therapy is well documented, it commonly causes severe toxicity. This study of the 467 systemic anticancer therapy agents currently approved globally for clinical and/or research purposes found that peripheral neurotoxicity is associated with 45% of classical chemotherapies, 21% of targeted ...
Cassie Higgins   +3 more
wiley   +1 more source

Home - About - Disclaimer - Privacy