Results 171 to 180 of about 105,114 (279)

Gemcitabine-Based Bladder Preservation in BCG-Unresponsive High-Risk NMIBC: Evidence, Limitations, and Clinical Positioning. [PDF]

Biomedicines
Kaltsas A, Papathanasiou K, Giannakodimos I, Zachariou A, Hoang NPC, Dung MBT, Hung TV, Chrisofos M, Sofikitis N, Dimitriadis F.   +9 more
europepmc   +1 more source

Updated EAACI Statement on Drug Hypersensitivity Skin Testing: Methodology and Non‐Irritative Concentrations

Allergy, EarlyView.
ABSTRACT These updated EAACI guidelines aim to standardize skin testing methodologies for both immediate and non‐immediate drug hypersensitivity reactions. For immediate reactions, the optimal testing window is 4–6 weeks post‐reaction; whereas beyond 6 months, false‐negative results increase.
Annick Barbaud, Lene Heise Garvey, Elizabeth Phillips, Michael Ardern‐Jones, Sevim Bavbek, Patrizia Bonadonna, Jean‐Christoph Caubet, Ana‐Maria Copaescu, Valentina Gueli, Jose Julio Laguna, Ricardo Madrigal‐Burgaleta, Francesca Mori, Vito Sabato, Maria J Torres, Knut Brockow   +14 more
wiley   +1 more source

Gemcitabine-based chemotherapy for advanced biliary tract carcinomas. [PDF]

Cochrane Database Syst Rev
Awedew AF, Fentahun Emrie A, Jegnie M, Morales L, supported by the Cochrane Hepato-Biliary Group.   +4 more
europepmc   +1 more source

Retrospective Study of Hepatotoxicity of Gemcitabine （Gemzar®）as First-line Chemotherapy in Non-Small Cell Lung Cancer

, 2007
在非小細胞肺癌（Non-small cell lung cancer）之治療藥物中，gemcitabine（Gemzar®）被使用作為後期（advanced）患者之標準療法用藥之一，和其他細胞毒性（cytotoxic）藥物比較起來，其副作用通常較為輕微。但肝毒性（hepatotoxicity）之發生並不少見（約20~50%），表現多為短暫、無症狀且很快恢復之肝酵素升高，很少會持續惡化；除此之外，近年來，越來越多之案例報告顯示gemcitabine有可能造成嚴重肝毒性，如肝臟靜脈阻塞疾病 ...
Wu, Ying-Hui, 吳盈慧
core  

Androgen Receptor Expression in Urothelial Bladder Cancer—A Systematic Review and Meta‐Analysis

ANZ Journal of Surgery, EarlyView.
ABSTRACT Background Bladder cancer is a globally prevalent malignancy with a marked male predominance. Over the past decade, the androgen receptor has been investigated as a potential contributor to bladder cancer pathophysiology. Androgen receptor expression is most commonly assessed via immunohistochemistry, but its association with pathological ...
Alex Buckby, Mandana Gholami, Matthew Hong, Michael O'Callaghan   +3 more
wiley   +1 more source

BACE2 Promotes Bladder Cancer Chemoresistance Through Proteolytic Activation of JAG1-Notch Signaling. [PDF]

Cancer Innov
Li Z, Li S, Liu Z, Sun Y, Zhang Y.
europepmc   +1 more source

Glofitamab in combination with immunochemotherapy in patients with relapsed/refractory B‐cell non‐Hodgkin lymphoma: Phase 1b dose‐escalation study

British Journal of Haematology, EarlyView.
Summary Glofitamab was investigated with obinutuzumab/rituximab plus cyclophosphamide, doxorubicin, vincristine and prednisone (G/R‐CHOP) in patients with relapsed/refractory B‐cell non‐Hodgkin lymphoma (B‐NHL) who had ≥1 prior obinutuzumab/rituximab‐containing therapy (NCT03467373). The primary end‐point was to determine the optimal biological dose of
William Townsend, Nilanjan Ghosh, Martin Hutchings, Michael Dickinson, Monica Tani, Armando Santoro, Michael Crump, Amitkumar Mehta, Reinhard Marks, Martin Weisser, Martin Barrett, Chun Wu, Derrick Kaufman, Katharina Lechner, Pauline Baumlin, Pontus Lundberg, Max S. Topp   +16 more
wiley   +1 more source

CPT1A through succinylation regulates the CTCF/LINC01503‒91aa feedback loop to promote gemcitabine resistance in pancreatic ductal adenocarcinoma. [PDF]

Clin Transl Med
Fang DL, Lu SY, Liu ZD, Xu QC, Yu YY, Zhu YQ, Ma MJ, Ye JY, Yin XY.   +8 more
europepmc   +1 more source

First‐in‐human outpatient management of recurrent NMIBC with the Multi4 instrument

BJU International, EarlyView.
Objectives To evaluate the feasibility, safety and diagnostic performance of outpatient management of recurrent non‐muscle‐invasive bladder cancer (NMIBC) under local anaesthesia using the Multi4 instrument, a series of preclinical studies were performed followed by a first‐in‐human clinical investigation.
Miden Melle‐Hannah, Henrik Kjölhede, Henrik Bäckdahl, Martin E. Johansson, Joakim Håkansson   +4 more
wiley   +1 more source

Mitophagy-Competent Cancer-Associated Fibroblasts Fuel Chemoresistance by Rewiring Pyrimidine Metabolism in Pancreatic Cancer. [PDF]

Cancer Res
Zhang S, Yuan H, Guo M, Zhou Z, Hu Y, Lv G, Qi H, Guo Y, Han J, Bronze MS, Houchen CW, Li M, Liu M.   +12 more
europepmc   +1 more source