Results 1 to 10 of about 586,062 (116)

Gene-environment interaction in functional hypothalamic amenorrhea [PDF]

Frontiers in Endocrinology
Functional hypothalamic amenorrhea (FHA) is a common cause of amenorrhea and chronic anovulation in adolescent girls and young women, diagnosed after excluding other organic causes.
Federica Barbagallo, David Bosoni, Valeria Perone, Valeria Perone, Laura Cucinella, Laura Cucinella, Davide Dealberti, Rossella Cannarella, Rossella Cannarella, Aldo E. Calogero, Rossella E. Nappi, Rossella E. Nappi   +11 more
doaj   +2 more sources

Gene-Environment Interaction Loci Associated with Refractive Error: SCAMPI Analysis [PDF]

Ophthalmology Science
Purpose: To compare the performance of a novel method for identifying candidate gene-environment interaction loci, Scalable Cauchy Aggregate test using Multiple Phenotypes to test Interactions (SCAMPI) (doi:10.1101/2024.09.10.612314v1), to widely used ...
Xi He, MSc, MD, Louise Terry, PhD, Jeremy A. Guggenheim, PhD, Naomi Allen, Tariq Aslam, Denize Atan, Konstantinos Balaskas, Sarah Barman, Jenny Barrett, Paul Bishop, Graeme Black, Tasanee Braithwaite, Roxana Carare, Usha Chakravarthy, Michelle Chan, Sharon Chua, Annegret Dahlmann-Noor, Alexander Day, Parul Desai, Bal Dhillon, Andrew Dick, Alexander Doney, Cathy Egan, Sarah Ennis, Paul Foster, Marcus Fruttiger, John Gallacher, David (Ted) Garway-Heath, Jane Gibson, Jeremy Guggenheim, Chris Hammond, Alison Hardcastley, Simon Harding, Ruth Hogg, Pirro Hysi, Pearse Keane, Sir Peng Tee Khaw, Anthony Khawaja, Gerassimos Lascaratos, Thomas Littlejohns, Andrew Lotery, Robert Luben, Phil Luthert, Tom Macgillivray, Sarah Mackie, Savita Madhusudhan, Bernadette Mcguinness, Gareth Mckay, Martin Mckibbint, Tony Moore, James Morgan, Eoin O'Sullivan, Richard Oram, Chris Owen, Praveen Patel, Euan Paterson, Tunde Peto, Axel Petzold, Nikolas Pontikos, Jugnoo Rahi, Alicja Rudnicka, Naveed Sattar, Jay Self, Panagiotis Sergouniotis, Sobha Sivaprasad, David Steel, Irene Stratton, Nicholas Strouthidis, Cathie Sudlow, Zihan Sun, Robyn Tapp, Dhanes Thomas, Mervyn Thomas, Emanuele Trucco, Adnan Tufail, Ananth Viswanathan, Veronique Vitart, Mike Weedon, Katie Williams, Cathy Williams, Jayne Woodside, Max Yates, Yalin Zheng   +82 more
doaj   +2 more sources

Genetic susceptibility shaped by biological state: beyond gene-environment interaction [PDF]

Frontiers in Genetics
This mini-review proposes a state-aware approach for interpreting gene-environment interaction (G × E). Biological state is the internal condition in which genetic susceptibility becomes functional. A measured exposure may precede that state, reflect it,
Hui-Qi Qu, Hakon Hakonarson, Hakon Hakonarson, Hakon Hakonarson, Hakon Hakonarson, Hakon Hakonarson   +5 more
doaj   +2 more sources

Interactive effects between lead-cadmium co-exposure and VEGFA gene polymorphisms on renal dysfunction: a gene–environment interaction study [PDF]

Frontiers in Public Health
BackgroundLead (Pb) and cadmium (Cd) are common persistent environmental pollutants, may cause renal dysfunction following long-term exposure. This study investigated whether vascular endothelial growth factor a (VEGFA) gene polymorphisms modify the ...
Yaotang Deng, Yaotang Deng, Yunman Wen, Weixia Duan, Zhiqiang Zhao, Guoliang Li, Jiazhen Zhou, Le Yang, Jieyi Yang, Yapei Sun, Manyi Qiu, Lili Liu   +11 more
doaj   +2 more sources

Exploring the influence of the DRD2 gene on mathematical ability: perspectives of gene association and gene-environment interaction [PDF]

BMC Psychology
Mathematical ability is influenced by genes and environment. This study focused on the effect of DRD2, a candidate gene for working memory, on mathematical ability.
Qing Yang, Ximiao Zhang, Liming Zhang, Chen Cheng, Jingjing Zhao   +4 more
doaj   +2 more sources

Gene-environment interaction in the pathophysiology of type 1 diabetes [PDF]

Frontiers in Endocrinology
Type 1 diabetes (T1D) is a complex metabolic autoimmune disorder that affects millions of individuals worldwide and often leads to significant comorbidities.
Rahul Mittal, Nathanael Camick, Nathanael Camick, Joana R. N. Lemos, Khemraj Hirani   +4 more
doaj   +2 more sources

Gene-environment interaction analysis of school quality and educational inequality [PDF]

npj Science of Learning
We study to what extent schools increase or decrease environmental and genetic influences on educational performance. Building on behavioral genetics literature on gene-environment interactions and sociological literature on the compensating and ...
Kim Stienstra, Antonie Knigge, Ineke Maas   +2 more
doaj   +2 more sources

Mito-SiPE is a sequence-independent and PCR-free mtDNA enrichment method for accurate ultra-deep mitochondrial sequencing

Communications Biology, 2022
Mito-SiPE is a mitochondrial DNA (mtDNA) enrichment method that can derive high-quality mtDNA for rare heteroplasmy analysis, without relying on PCR or probes.
Darren J. Walsh, David J. Bernard, Faith Pangilinan, Madison Esposito, Denise Harold, Anne Parle-McDermott, Lawrence C. Brody   +6 more
doaj   +1 more source

Gene–Environment Interactions in Severe Mental Illness [PDF]

Frontiers in Psychiatry, 2014
Severe mental illness (SMI) is a broad category that includes schizophrenia, bipolar disorder, and severe depression. Both genetic disposition and environmental exposures play important roles in the development of SMI. Multiple lines of evidence suggest that the roles of genetic and environmental factors depend on each other.
Rudolf eUher, Rudolf eUher
openaire   +3 more sources

Gene-environment interaction in yeast gene expression. [PDF]

PLoS Biology, 2008
The effects of genetic variants on phenotypic traits often depend on environmental and physiological conditions, but such gene-environment interactions are poorly understood.
Erin N Smith, Leonid Kruglyak
doaj   +1 more source