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Efficient gene–environment interaction testing through bootstrap aggregating [PDF]

open access: yesScientific Reports, 2023
Gene–environment (GxE) interactions are an important and sophisticated component in the manifestation of complex phenotypes. Simple univariate tests lack statistical power due to the need for multiple testing adjustment and not incorporating potential ...
Michael Lau   +3 more
doaj   +2 more sources

Mito-SiPE is a sequence-independent and PCR-free mtDNA enrichment method for accurate ultra-deep mitochondrial sequencing

open access: yesCommunications Biology, 2022
Mito-SiPE is a mitochondrial DNA (mtDNA) enrichment method that can derive high-quality mtDNA for rare heteroplasmy analysis, without relying on PCR or probes.
Darren J. Walsh   +6 more
doaj   +1 more source

Gene-environment interaction in yeast gene expression. [PDF]

open access: yesPLoS Biology, 2008
The effects of genetic variants on phenotypic traits often depend on environmental and physiological conditions, but such gene-environment interactions are poorly understood.
Erin N Smith, Leonid Kruglyak
doaj   +1 more source

Gene–gene and gene-environment interactions on cord blood total IgE in Chinese Han children

open access: yesAllergy, Asthma & Clinical Immunology, 2021
Background IL13, IL4, IL4RA, FCER1B and ADRB2 are susceptible genes of asthma and atopy. Our previous study has found gene–gene interactions on asthma between these genes in Chinese Han children. Whether the interactions begin in fetal stage, and whether
Li Hua   +18 more
doaj   +1 more source

Mutual information for testing gene-environment interaction. [PDF]

open access: yesPLoS ONE, 2009
Despite current enthusiasm for investigation of gene-gene interactions and gene-environment interactions, the essential issue of how to define and detect gene-environment interactions remains unresolved.
Xuesen Wu, Li Jin, Momiao Xiong
doaj   +1 more source

Gene-environment interaction in molar-incisor hypomineralization.

open access: yesPLoS ONE, 2021
Molar incisor hypomineralization (MIH) is an enamel condition characterized by lesions ranging in color from white to brown which present rapid caries progression, and mainly affects permanent first molars and incisors. These enamel defects usually occur
Mariana Bezamat   +22 more
doaj   +1 more source

How ambient temperature affects the heading date of foxtail millet (Setaria italica)

open access: yesFrontiers in Plant Science, 2023
Foxtail millet (Setaria italica), a short-day plant, is one of the important crops for food security encountering climate change, particularly in regions where it is a staple food.
Ya-Chen Huang   +8 more
doaj   +1 more source

Signatures of adaptation in myopia-related genes on the sunlight exposure hypothesis

open access: yesJournal of Physiological Anthropology, 2023
Background Myopia is a common eye disorder that results from gene-environment interactions. The prevalence of myopia varies across populations, and exposure to bright sunlight may prevent its development.
Tian Xia, Kazuhiro Nakayama
doaj   +1 more source

Two-dimensional three-body quadrupole-quadrupole interactions [PDF]

open access: yes, 2021
Similar to interactions between dipoles, or van der Waals interactions, quadrupole-quadrupole interactions are interactions between quadrupoles. In this article, we study the quadrupole interactions between highly excited atoms or Rydberg atoms. In addition, unlike many other calculations, in which the primary focus was on the one-dimensional two-body ...
arxiv   +1 more source

DeepSI: Interactive Deep Learning for Semantic Interaction [PDF]

open access: yesIUI '21: 26th International Conference on Intelligent User Interfaces, College Station, TX, USA, April 2021, 2023
In this paper, we design novel interactive deep learning methods to improve semantic interactions in visual analytics applications. The ability of semantic interaction to infer analysts' precise intents during sensemaking is dependent on the quality of the underlying data representation.
arxiv   +1 more source

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