Gene-environment interaction in molar-incisor hypomineralization.
PLoS ONE, 2021Molar incisor hypomineralization (MIH) is an enamel condition characterized by lesions ranging in color from white to brown which present rapid caries progression, and mainly affects permanent first molars and incisors. These enamel defects usually occur
Mariana Bezamat+22 more
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Gene–Environment Interaction in Major Depression: Focus on Experience-Dependent Biological Systems [PDF]
Frontiers in Psychiatry, 2015Major depressive disorder (MDD) is a multifactorial and polygenic disorder, where multiple and partially overlapping sets of susceptibility genes interact each other and with the environment, predisposing individuals to the development of the illness. Thus, MDD results from a complex interplay of vulnerability genes and environmental factors that act ...
Nicola eLopizzo+8 more
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Gene-Environment Interactions in Stress Response Contribute Additively to a Genotype-Environment Interaction. [PDF]
PLoS Genetics, 2016How combinations of gene-environment interactions collectively give rise to genotype-environment interactions is not fully understood. To shed light on this problem, we genetically dissected an environment-specific poor growth phenotype in a cross of two
Takeshi Matsui, Ian M Ehrenreich
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Gene-environment interaction and maternal arsenic methylation efficiency during pregnancy
Environment International, 2019Background: Single nucleotide polymorphisms (SNPs) may influence arsenic methylation efficiency, affecting arsenic metabolism. Whether gene-environment interactions affect arsenic metabolism during pregnancy remains unclear, which may have implications ...
Shangzhi Gao+9 more
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Mito-SiPE is a mitochondrial DNA (mtDNA) enrichment method that can derive high-quality mtDNA for rare heteroplasmy analysis, without relying on PCR or probes.
Darren J. Walsh+6 more
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Gene–Environment Interactions in Severe Mental Illness [PDF]
Frontiers in Psychiatry, 2014Severe mental illness (SMI) is a broad category that includes schizophrenia, bipolar disorder, and severe depression. Both genetic disposition and environmental exposures play important roles in the development of SMI. Multiple lines of evidence suggest that the roles of genetic and environmental factors depend on each other.
Rudolf eUher, Rudolf eUher
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Gene-environment interaction in yeast gene expression. [PDF]
PLoS Biology, 2008The effects of genetic variants on phenotypic traits often depend on environmental and physiological conditions, but such gene-environment interactions are poorly understood.
Erin N Smith, Leonid Kruglyak
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A comprehensive gene–environment interaction analysis in Ovarian Cancer using genome‐wide significant common variants [PDF]
International Journal of Cancer, 2019As a follow‐up to genome‐wide association analysis of common variants associated with ovarian carcinoma (cancer), our study considers seven well‐known ovarian cancer risk factors and their interactions with 28 genome‐wide significant common genetic variants.
Elisa V. Bandera+63 more
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Gene–gene and gene-environment interactions on cord blood total IgE in Chinese Han children
Allergy, Asthma & Clinical Immunology, 2021Background IL13, IL4, IL4RA, FCER1B and ADRB2 are susceptible genes of asthma and atopy. Our previous study has found gene–gene interactions on asthma between these genes in Chinese Han children. Whether the interactions begin in fetal stage, and whether
Li Hua+18 more
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Mutual information for testing gene-environment interaction. [PDF]
PLoS ONE, 2009Despite current enthusiasm for investigation of gene-gene interactions and gene-environment interactions, the essential issue of how to define and detect gene-environment interactions remains unresolved.
Xuesen Wu, Li Jin, Momiao Xiong
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