Results 1 to 10 of about 5,649,635 (271)

Gene-environment interaction in molar-incisor hypomineralization.

open access: yesPLoS ONE, 2021
Molar incisor hypomineralization (MIH) is an enamel condition characterized by lesions ranging in color from white to brown which present rapid caries progression, and mainly affects permanent first molars and incisors. These enamel defects usually occur
Mariana Bezamat   +22 more
doaj   +2 more sources

Gene–Environment Interaction in Major Depression: Focus on Experience-Dependent Biological Systems [PDF]

open access: yesFrontiers in Psychiatry, 2015
Major depressive disorder (MDD) is a multifactorial and polygenic disorder, where multiple and partially overlapping sets of susceptibility genes interact each other and with the environment, predisposing individuals to the development of the illness. Thus, MDD results from a complex interplay of vulnerability genes and environmental factors that act ...
Nicola eLopizzo   +8 more
openaire   +7 more sources

Gene-Environment Interactions in Stress Response Contribute Additively to a Genotype-Environment Interaction. [PDF]

open access: yesPLoS Genetics, 2016
How combinations of gene-environment interactions collectively give rise to genotype-environment interactions is not fully understood. To shed light on this problem, we genetically dissected an environment-specific poor growth phenotype in a cross of two
Takeshi Matsui, Ian M Ehrenreich
doaj   +2 more sources

Gene-environment interaction and maternal arsenic methylation efficiency during pregnancy

open access: yesEnvironment International, 2019
Background: Single nucleotide polymorphisms (SNPs) may influence arsenic methylation efficiency, affecting arsenic metabolism. Whether gene-environment interactions affect arsenic metabolism during pregnancy remains unclear, which may have implications ...
Shangzhi Gao   +9 more
doaj   +2 more sources

Mito-SiPE is a sequence-independent and PCR-free mtDNA enrichment method for accurate ultra-deep mitochondrial sequencing

open access: yesCommunications Biology, 2022
Mito-SiPE is a mitochondrial DNA (mtDNA) enrichment method that can derive high-quality mtDNA for rare heteroplasmy analysis, without relying on PCR or probes.
Darren J. Walsh   +6 more
doaj   +1 more source

Gene–Environment Interactions in Severe Mental Illness [PDF]

open access: yesFrontiers in Psychiatry, 2014
Severe mental illness (SMI) is a broad category that includes schizophrenia, bipolar disorder, and severe depression. Both genetic disposition and environmental exposures play important roles in the development of SMI. Multiple lines of evidence suggest that the roles of genetic and environmental factors depend on each other.
Rudolf eUher, Rudolf eUher
openaire   +3 more sources

Gene-environment interaction in yeast gene expression. [PDF]

open access: yesPLoS Biology, 2008
The effects of genetic variants on phenotypic traits often depend on environmental and physiological conditions, but such gene-environment interactions are poorly understood.
Erin N Smith, Leonid Kruglyak
doaj   +1 more source

A comprehensive gene–environment interaction analysis in Ovarian Cancer using genome‐wide significant common variants [PDF]

open access: yesInternational Journal of Cancer, 2019
As a follow‐up to genome‐wide association analysis of common variants associated with ovarian carcinoma (cancer), our study considers seven well‐known ovarian cancer risk factors and their interactions with 28 genome‐wide significant common genetic variants.
Elisa V. Bandera   +63 more
openaire   +6 more sources

Gene–gene and gene-environment interactions on cord blood total IgE in Chinese Han children

open access: yesAllergy, Asthma & Clinical Immunology, 2021
Background IL13, IL4, IL4RA, FCER1B and ADRB2 are susceptible genes of asthma and atopy. Our previous study has found gene–gene interactions on asthma between these genes in Chinese Han children. Whether the interactions begin in fetal stage, and whether
Li Hua   +18 more
doaj   +1 more source

Mutual information for testing gene-environment interaction. [PDF]

open access: yesPLoS ONE, 2009
Despite current enthusiasm for investigation of gene-gene interactions and gene-environment interactions, the essential issue of how to define and detect gene-environment interactions remains unresolved.
Xuesen Wu, Li Jin, Momiao Xiong
doaj   +1 more source

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