Gene-environment interaction in functional hypothalamic amenorrhea [PDF]
Frontiers in EndocrinologyFunctional hypothalamic amenorrhea (FHA) is a common cause of amenorrhea and chronic anovulation in adolescent girls and young women, diagnosed after excluding other organic causes.
Federica Barbagallo +11 more
doaj +2 more sources
Efficient gene–environment interaction testing through bootstrap aggregating [PDF]
Scientific Reports, 2023 Gene–environment (GxE) interactions are an important and sophisticated component in the manifestation of complex phenotypes. Simple univariate tests lack statistical power due to the need for multiple testing adjustment and not incorporating potential ...
Michael Lau +3 more
doaj +2 more sources
Exploring the influence of the DRD2 gene on mathematical ability: perspectives of gene association and gene-environment interaction [PDF]
BMC PsychologyMathematical ability is influenced by genes and environment. This study focused on the effect of DRD2, a candidate gene for working memory, on mathematical ability.
Qing Yang +4 more
doaj +2 more sources
Inference of gene-environment interaction from heterogeneous case-parent trios [PDF]
Frontiers in Genetics, 2023 Introduction: In genetic epidemiology, log-linear models of population risk may be used to study the effect of genotypes and exposures on the relative risk of a disease.
Pulindu Ratnasekera +2 more
doaj +2 more sources
Gene-environment interaction in the pathophysiology of type 1 diabetes [PDF]
Frontiers in EndocrinologyType 1 diabetes (T1D) is a complex metabolic autoimmune disorder that affects millions of individuals worldwide and often leads to significant comorbidities.
Rahul Mittal +4 more
doaj +2 more sources
Gene-environment interaction analysis of school quality and educational inequality [PDF]
npj Science of LearningWe study to what extent schools increase or decrease environmental and genetic influences on educational performance. Building on behavioral genetics literature on gene-environment interactions and sociological literature on the compensating and ...
Kim Stienstra +2 more
doaj +2 more sources
Communications Biology, 2022 Mito-SiPE is a mitochondrial DNA (mtDNA) enrichment method that can derive high-quality mtDNA for rare heteroplasmy analysis, without relying on PCR or probes.
Darren J. Walsh +6 more
doaj +1 more source
Gene–Environment Interactions in Severe Mental Illness [PDF]
Frontiers in Psychiatry, 2014 Severe mental illness (SMI) is a broad category that includes schizophrenia, bipolar disorder, and severe depression. Both genetic disposition and environmental exposures play important roles in the development of SMI. Multiple lines of evidence suggest that the roles of genetic and environmental factors depend on each other.
Rudolf eUher, Rudolf eUher
openaire +3 more sources
Gene-environment interaction in yeast gene expression. [PDF]
PLoS Biology, 2008 The effects of genetic variants on phenotypic traits often depend on environmental and physiological conditions, but such gene-environment interactions are poorly understood.
Erin N Smith, Leonid Kruglyak
doaj +1 more source
Gene–Environment Interaction in Major Depression: Focus on Experience-Dependent Biological Systems [PDF]
Frontiers in Psychiatry, 2015 Major depressive disorder (MDD) is a multifactorial and polygenic disorder, where multiple and partially overlapping sets of susceptibility genes interact each other and with the environment, predisposing individuals to the development of the illness. Thus, MDD results from a complex interplay of vulnerability genes and environmental factors that act ...
Nicola eLopizzo +8 more
openaire +6 more sources