Inference of gene-environment interaction from heterogeneous case-parent trios [PDF]
Frontiers in Genetics, 2023 Introduction: In genetic epidemiology, log-linear models of population risk may be used to study the effect of genotypes and exposures on the relative risk of a disease.
Pulindu Ratnasekera +2 more
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Gene-environment interaction: A genetic-epidemiological approach [PDF]
Journal of Medical Biochemistry, 2010 Classical epidemiology addresses the distribution and determinants of diseases in populations, and the factors associated with disease causation, with the aim of preventing disease. Both genetic and environmental factors may contribute to susceptibility,
Pekmezović Tatjana
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Gene–Environment Interaction in Major Depression: Focus on Experience-Dependent Biological Systems [PDF]
Frontiers in Psychiatry, 2015 Major depressive disorder (MDD) is a multifactorial and polygenic disorder, where multiple and partially overlapping sets of susceptibility genes interact each other and with the environment, predisposing individuals to the development of the illness. Thus, MDD results from a complex interplay of vulnerability genes and environmental factors that act ...
Nicola eLopizzo +8 more
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Gene–gene and gene-environment interactions on cord blood total IgE in Chinese Han children
Allergy, Asthma & Clinical Immunology, 2021 Background IL13, IL4, IL4RA, FCER1B and ADRB2 are susceptible genes of asthma and atopy. Our previous study has found gene–gene interactions on asthma between these genes in Chinese Han children. Whether the interactions begin in fetal stage, and whether
Li Hua +18 more
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Mutual information for testing gene-environment interaction. [PDF]
PLoS ONE, 2009 Despite current enthusiasm for investigation of gene-gene interactions and gene-environment interactions, the essential issue of how to define and detect gene-environment interactions remains unresolved.
Xuesen Wu, Li Jin, Momiao Xiong
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Gene-environment interaction in psychopathologies: stress-related genetic and epigenetic influences [PDF]
Klinik Psikoloji Dergisi, 2021 It has long been known that stressful life events are related to various psychological problems. The relationship between stress and psychiatric disorders has been further recognized due to reports of studies investigating interactions between biological
Esra Zıvralı Yarar
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Gene-environment interaction in molar-incisor hypomineralization.
PLoS ONE, 2021 Molar incisor hypomineralization (MIH) is an enamel condition characterized by lesions ranging in color from white to brown which present rapid caries progression, and mainly affects permanent first molars and incisors. These enamel defects usually occur
Mariana Bezamat +22 more
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Efficient gene–environment interaction testing through bootstrap aggregating
Scientific Reports, 2023 Gene–environment (GxE) interactions are an important and sophisticated component in the manifestation of complex phenotypes. Simple univariate tests lack statistical power due to the need for multiple testing adjustment and not incorporating potential ...
Michael Lau +3 more
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How ambient temperature affects the heading date of foxtail millet (Setaria italica)
Frontiers in Plant Science, 2023 Foxtail millet (Setaria italica), a short-day plant, is one of the important crops for food security encountering climate change, particularly in regions where it is a staple food.
Ya-Chen Huang +8 more
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Signatures of adaptation in myopia-related genes on the sunlight exposure hypothesis
Journal of Physiological Anthropology, 2023 Background Myopia is a common eye disorder that results from gene-environment interactions. The prevalence of myopia varies across populations, and exposure to bright sunlight may prevent its development.
Tian Xia, Kazuhiro Nakayama
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