Results 11 to 20 of about 12,471,578 (252)

Gene-environment interaction: A genetic-epidemiological approach [PDF]

open access: yesJournal of Medical Biochemistry, 2010
Classical epidemiology addresses the distribution and determinants of diseases in populations, and the factors associated with disease causation, with the aim of preventing disease. Both genetic and environmental factors may contribute to susceptibility,
Pekmezović Tatjana
doaj   +2 more sources

A flexible Bayesian model for studying gene-environment interaction. [PDF]

open access: yesPLoS Genetics, 2012
An important follow-up step after genetic markers are found to be associated with a disease outcome is a more detailed analysis investigating how the implicated gene or chromosomal region and an established environment risk factor interact to influence ...
Kai Yu   +6 more
doaj   +3 more sources

Gene–Environment Interactions in Severe Mental Illness [PDF]

open access: yesFrontiers in Psychiatry, 2014
Severe mental illness (SMI) is a broad category that includes schizophrenia, bipolar disorder, and severe depression. Both genetic disposition and environmental exposures play important roles in the development of SMI. Multiple lines of evidence suggest that the roles of genetic and environmental factors depend on each other.
Rudolf eUher, Rudolf eUher
openaire   +3 more sources

Gene–Environment Interaction in Major Depression: Focus on Experience-Dependent Biological Systems [PDF]

open access: yesFrontiers in Psychiatry, 2015
Major depressive disorder (MDD) is a multifactorial and polygenic disorder, where multiple and partially overlapping sets of susceptibility genes interact each other and with the environment, predisposing individuals to the development of the illness. Thus, MDD results from a complex interplay of vulnerability genes and environmental factors that act ...
Nicola eLopizzo   +8 more
openaire   +6 more sources

Mutual information for testing gene-environment interaction. [PDF]

open access: yesPLoS ONE, 2009
Despite current enthusiasm for investigation of gene-gene interactions and gene-environment interactions, the essential issue of how to define and detect gene-environment interactions remains unresolved.
Xuesen Wu, Li Jin, Momiao Xiong
doaj   +1 more source

Gene-environment interaction in psychopathologies: stress-related genetic and epigenetic influences [PDF]

open access: yesKlinik Psikoloji Dergisi, 2021
It has long been known that stressful life events are related to various psychological problems. The relationship between stress and psychiatric disorders has been further recognized due to reports of studies investigating interactions between biological
Esra Zıvralı Yarar
doaj   +1 more source

Gene-environment interaction in molar-incisor hypomineralization.

open access: yesPLoS ONE, 2021
Molar incisor hypomineralization (MIH) is an enamel condition characterized by lesions ranging in color from white to brown which present rapid caries progression, and mainly affects permanent first molars and incisors. These enamel defects usually occur
Mariana Bezamat   +22 more
doaj   +1 more source

How ambient temperature affects the heading date of foxtail millet (Setaria italica)

open access: yesFrontiers in Plant Science, 2023
Foxtail millet (Setaria italica), a short-day plant, is one of the important crops for food security encountering climate change, particularly in regions where it is a staple food.
Ya-Chen Huang   +8 more
doaj   +1 more source

Efficient gene–environment interaction testing through bootstrap aggregating

open access: yesScientific Reports, 2023
Gene–environment (GxE) interactions are an important and sophisticated component in the manifestation of complex phenotypes. Simple univariate tests lack statistical power due to the need for multiple testing adjustment and not incorporating potential ...
Michael Lau   +3 more
doaj   +1 more source

Signatures of adaptation in myopia-related genes on the sunlight exposure hypothesis

open access: yesJournal of Physiological Anthropology, 2023
Background Myopia is a common eye disorder that results from gene-environment interactions. The prevalence of myopia varies across populations, and exposure to bright sunlight may prevent its development.
Tian Xia, Kazuhiro Nakayama
doaj   +1 more source

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