Information-theoretic gene-gene and gene-environment interaction analysis of quantitative traits
BMC Genomics, 2009 Background The purpose of this research was to develop a novel information theoretic method and an efficient algorithm for analyzing the gene-gene (GGI) and gene-environmental interactions (GEI) associated with quantitative traits (QT).
Liu Song +4 more
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The lipoprotein lipase S447X polymorphism and plasma lipids
Journal of Lipid Research, 2004 We studied 4,058 subjects from a representative sample of the Singapore population 1) to determine the association between the S447X polymorphism at the LPL locus and serum lipid concentration in Chinese, Malays, and Asian Indians living in Singapore and
J. Lee +6 more
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Breast Cancer Research, 2023 Background Moderate to heavy alcohol consumption is associated with an increased risk of breast cancer. The etiologic role of genetic variation in genes involved in ethanol metabolism has not been established, with little information available among ...
Kristin L. Young +8 more
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The Genetic Architecture of Noise-Induced Hearing Loss: Evidence for a Gene-by-Environment Interaction. [PDF]
, 2016 The discovery of environmentally specific genetic effects is crucial to the understanding of complex traits, such as susceptibility to noise-induced hearing loss (NIHL).
Allayee, Hooman +10 more
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Replication of Gene-by-psychosocial Stress Interaction Effects on Central Adiposity in a Korean Population [PDF]
Journal of Preventive Medicine and Public Health, 2016 Objectives Central obesity plays a major role in the development of many chronic diseases, including cardiovascular disease and cancer. Chronic stress may be involved in the pathophysiology of central obesity.
Hyun-Jin Kim +2 more
doaj +1 more source
Gene-environment interaction: A genetic-epidemiological approach [PDF]
Journal of Medical Biochemistry, 2010 Classical epidemiology addresses the distribution and determinants of diseases in populations, and the factors associated with disease causation, with the aim of preventing disease. Both genetic and environmental factors may contribute to susceptibility,
Pekmezović Tatjana
doaj
Natural variation in abiotic stress responsive gene expression and local adaptation to climate in Arabidopsis thaliana. [PDF]
, 2014 Gene expression varies widely in natural populations, yet the proximate and ultimate causes of this variation are poorly known. Understanding how variation in gene expression affects abiotic stress tolerance, fitness, and adaptation is central to the ...
Des Marais, David L +7 more
core +2 more sources
Inference of gene-environment interaction from heterogeneous case-parent trios
Frontiers in Genetics, 2023 Introduction: In genetic epidemiology, log-linear models of population risk may be used to study the effect of genotypes and exposures on the relative risk of a disease.
Pulindu Ratnasekera +2 more
doaj +1 more source
Stacking-induced fluorescence increase reveals allosteric interactions through DNA [PDF]
, 2018 From gene expression to nanotechnology, understanding and controlling DNA requires a detailed knowledge of its higher order structure and dynamics. Here we take advantage of the environment-sensitive photoisomerization of cyanine dyes to probe local and ...
Lopez, Sergio G. +4 more
core +1 more source
Environment-Gene interaction in common complex diseases: New approaches
AIMS Molecular Science, 2014 Approximately 100,000 different environmental chemicals that are in use as high production volume chemicals confront us in our daily lives. Many of the chemicals we encounter are persistent and have long half-lives in the environment and our bodies ...
William A. Toscano, Jr. +4 more
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