Candidate gene-environment interactions in substance abuse: A systematic review.
PLoS ONE, 2023 BackgroundThe abuse of psychogenic drugs can lead to multiple health-related problems. Genetic and environmental vulnerabilities are factors in the emergence of substance use disorders.
Zheng Jiang, Zidong Chen, Xi Chen
doaj +1 more source
Differential expression of placental glucocorticoid receptors and growth arrest-specific transcript 5 in term and preterm pregnancies: evidence for involvement of maternal stress. [PDF]
, 2014 This article has been made available through the Brunel Open Access Publishing Fund.Pregnancy-specific stress predicts birth outcomes. We hypothesized that there is a maternal stress-GR interaction that can influence fetal birth weight.
Gidron, Y +6 more
core +3 more sources
The impact of imprecisely measured covariates on estimating gene-environment interactions [PDF]
, 2006 BACKGROUND The effects of measurement error in epidemiological exposures and confounders on estimated effects of exposure are well described, but the effects on estimates for gene-environment interactions has received rather less attention.
Cade, J.E. +2 more
core +2 more sources
PLoS Genetics, 2017 Previous genome-wide association studies (GWAS) have identified hundreds of genetic loci to be associated with body mass index (BMI) and risk of obesity.
M. Rask-Andersen +3 more
semanticscholar +1 more source
Genetic interactions affecting human gene expression identified by variance association mapping
eLife, 2014 Non-additive interaction between genetic variants, or epistasis, is a possible explanation for the gap between heritability of complex traits and the variation explained by identified genetic loci.
Andrew Anand Brown +9 more
doaj +1 more source
Hawaiian Picture‐Winged Drosophila Exhibit Adaptive Population Divergence along a Narrow Climatic Gradient on Hawaii Island [PDF]
, 2019 1. Anthropogenic influences on global processes and climatic conditions are increasingly affecting ecosystems throughout the world. 2. Hawaii Island’s native ecosystems are well studied and local long‐term climatic trends well documented, making these ...
Bellinger, M. Renee +2 more
core +2 more sources
Information-theoretic gene-gene and gene-environment interaction analysis of quantitative traits
BMC Genomics, 2009 Background The purpose of this research was to develop a novel information theoretic method and an efficient algorithm for analyzing the gene-gene (GGI) and gene-environmental interactions (GEI) associated with quantitative traits (QT).
Liu Song +4 more
doaj +1 more source
Metabolic syndrome, diabetes and atherosclerosis: Influence of gene-environment interaction [PDF]
, 2009 Despite remarkable progress in diagnosis and understanding of risk factors, cardiovascular disease (CVD) remains still the leading cause of morbidity and mortality in the world\u27s developed countries.
Andreassi, Maria Grazia
core +1 more source
Breast Cancer Research, 2023 Background Moderate to heavy alcohol consumption is associated with an increased risk of breast cancer. The etiologic role of genetic variation in genes involved in ethanol metabolism has not been established, with little information available among ...
Kristin L. Young +8 more
doaj +1 more source
Gene–environment interaction and risk of breast cancer
British Journal of Cancer, 2016 Hereditary, genetic factors as well as lifestyle and environmental factors, for example, parity and body mass index, predict breast cancer development.
A. Rudolph, J. Chang-Claude, M. Schmidt
semanticscholar +1 more source