Results 71 to 80 of about 1,093,414 (290)
Neurobiology of Disease, 2013 Interactions between genetic factors and environmental exposures are thought to be major contributors to the etiology of Parkinson's disease. While such interactions are poorly defined and incompletely understood, recent epidemiological studies have ...
Jason R. Cannon, J. Timothy Greenamyre
doaj +1 more source
Cross-cultural comparison of genetic and cultural transmission of smoking initiation using an extended twin kinship model [PDF]
, 2018 Background: Considerable evidence from twin and adoption studies indicates that genetic and shared environmental factors play a role in the initiation of smoking behavior.
Eaves, Lindon J +6 more
core +2 more sources
FEBS Letters, EarlyView.Three‐dimensional (3D) biological systems have become key tools in lymphoma research, offering reliable in vitro and ex vivo platforms to explore pathogenesis and support precision medicine. This review highlights current 3D non‐Hodgkin lymphoma models, detailing their features, advantages, and limitations, and provides a broad perspective on future ...
Carla Faria +3 more
wiley +1 more source
Frontiers in Genetics, 2020 Gene–environment interaction is a key part of evolutionary biology, animal, and plant breeding, and a number of health sciences, like epidemiology and precision medicine.
José M. Álvarez-Castro
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A new clinical evidence-based gene-environment interaction model of depression. [PDF]
, 2016 In our current understanding of mood disorders, the role of genes is diverse including the mediation of the effects of provoking and protective factors.
Bagdy, György +2 more
core
Genetic Influences on Peer and Family Relationships across Adolescent Development: Introduction to the Special Issue [PDF]
, 2015 Nearly all aspects of human development are influenced by genetic and environmental factors, which conjointly shape development through several gene-environment interplay mechanisms.
DiLalla, Lisabeth Fisher +1 more
core +2 more sources
From omics to AI—mapping the pathogenic pathways in type 2 diabetes
FEBS Letters, EarlyView.Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan +2 more
wiley +1 more source
Social Integration and Sleep Disturbance: A Gene-Environment Interaction Study
Collabra, 2016 Objective: Low levels of perceived social integration, or loneliness, are associated with increased risk for a range of poor health outcomes. Sleep disturbance plays a central role in the evolutionary theory of loneliness, which provides a mechanistic ...
David A. Sbarra
doaj +1 more source
ERBIN limits epithelial cell plasticity via suppression of TGF‐β signaling
FEBS Letters, EarlyView.In breast and lung cancer patients, low ERBIN expression correlates with poor clinical outcomes. Here, we show that ERBIN inhibits TGF‐β‐induced epithelial‐to‐mesenchymal transition in NMuMG breast and A549 lung adenocarcinoma cell lines. ERBIN suppresses TGF‐β/SMAD signaling and reduces TGF‐β‐induced ERK phosphorylation.
Chao Li +3 more
wiley +1 more source
Epigenetic metaphors: an interdisciplinary translation of encoding and decoding
New Genetics and Society, 2019 Looking at the new and often disputed science of epigenetics, we examined the challenges faced by scientists when they communicate scientific research to the public. We focused on the use of metaphors to illustrate notions of epigenetics and genetics. We
Aviad Raz +2 more
doaj +1 more source