Gene-environment interaction in functional hypothalamic amenorrhea [PDF]
Frontiers in EndocrinologyFunctional hypothalamic amenorrhea (FHA) is a common cause of amenorrhea and chronic anovulation in adolescent girls and young women, diagnosed after excluding other organic causes.
Federica Barbagallo +11 more
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Efficient gene–environment interaction testing through bootstrap aggregating [PDF]
Scientific Reports, 2023 Gene–environment (GxE) interactions are an important and sophisticated component in the manifestation of complex phenotypes. Simple univariate tests lack statistical power due to the need for multiple testing adjustment and not incorporating potential ...
Michael Lau +3 more
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A unifying approach for haplotype analysis of quantitative traits in family-based association studies: Testing and estimating gene-environment interactions with complex exposure variables [PDF]
, 2006 We propose robust and e±cient tests and estimators for gene-environment/gene-drug interactions in family-based association studies. The methodology is designed for studies in which haplotypes, quantitative pheno- types and complex exposure/treatment ...
Stijn Vansteelandt, Christoph Lange
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Modeling Gene-Environment Interaction for the Risk of Non-hodgkin Lymphoma [PDF]
Frontiers in Oncology, 2019 Background: Non-hodgkin lymphoma (NHL) is one of the most common and deadly cancers. There is limited analysis of gene-environment interactions for the risk of NHL. This study intends to explore the interactions between genetic variants and environmental
Jiahui Zhang +8 more
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Exploring the influence of the DRD2 gene on mathematical ability: perspectives of gene association and gene-environment interaction [PDF]
BMC PsychologyMathematical ability is influenced by genes and environment. This study focused on the effect of DRD2, a candidate gene for working memory, on mathematical ability.
Qing Yang +4 more
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Gene-environment interaction in the pathophysiology of type 1 diabetes [PDF]
Frontiers in EndocrinologyType 1 diabetes (T1D) is a complex metabolic autoimmune disorder that affects millions of individuals worldwide and often leads to significant comorbidities.
Rahul Mittal +4 more
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Gene-environment interaction analysis of school quality and educational inequality [PDF]
npj Science of LearningWe study to what extent schools increase or decrease environmental and genetic influences on educational performance. Building on behavioral genetics literature on gene-environment interactions and sociological literature on the compensating and ...
Kim Stienstra +2 more
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The Familial Clustering of Age at Menarche in Extended Twin Families [PDF]
, 2007 The timing of puberty is complex, possibly involving many genetic factors that may interact with environmental influences. Familial resemblance for age at menarche was studied in a sample of 4,995 female twins, 1,296 sisters, 2,946 mothers and 635 female
A Must +26 more
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Communications Biology, 2022 Mito-SiPE is a mitochondrial DNA (mtDNA) enrichment method that can derive high-quality mtDNA for rare heteroplasmy analysis, without relying on PCR or probes.
Darren J. Walsh +6 more
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Gene-environment interaction in yeast gene expression. [PDF]
PLoS Biology, 2008 The effects of genetic variants on phenotypic traits often depend on environmental and physiological conditions, but such gene-environment interactions are poorly understood.
Erin N Smith, Leonid Kruglyak
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