Results 1 to 10 of about 762,158 (316)

Efficient gene–environment interaction testing through bootstrap aggregating [PDF]

Scientific Reports, 2023
Gene–environment (GxE) interactions are an important and sophisticated component in the manifestation of complex phenotypes. Simple univariate tests lack statistical power due to the need for multiple testing adjustment and not incorporating potential ...
Michael Lau, Sara Kress, Tamara Schikowski, Holger Schwender   +3 more
doaj   +2 more sources

Gene-environment interaction in functional hypothalamic amenorrhea [PDF]

Frontiers in Endocrinology
Functional hypothalamic amenorrhea (FHA) is a common cause of amenorrhea and chronic anovulation in adolescent girls and young women, diagnosed after excluding other organic causes.
Federica Barbagallo, David Bosoni, Valeria Perone, Valeria Perone, Laura Cucinella, Laura Cucinella, Davide Dealberti, Rossella Cannarella, Rossella Cannarella, Aldo E. Calogero, Rossella E. Nappi, Rossella E. Nappi   +11 more
doaj   +2 more sources

Inference of gene-environment interaction from heterogeneous case-parent trios [PDF]

Frontiers in Genetics, 2023
Introduction: In genetic epidemiology, log-linear models of population risk may be used to study the effect of genotypes and exposures on the relative risk of a disease.
Pulindu Ratnasekera, Jinko Graham , Brad McNeney   +2 more
doaj   +2 more sources

Exploring the influence of the DRD2 gene on mathematical ability: perspectives of gene association and gene-environment interaction [PDF]

BMC Psychology
Mathematical ability is influenced by genes and environment. This study focused on the effect of DRD2, a candidate gene for working memory, on mathematical ability.
Qing Yang, Ximiao Zhang, Liming Zhang, Chen Cheng, Jingjing Zhao   +4 more
doaj   +2 more sources

Gene-environment interaction in the pathophysiology of type 1 diabetes [PDF]

Frontiers in Endocrinology
Type 1 diabetes (T1D) is a complex metabolic autoimmune disorder that affects millions of individuals worldwide and often leads to significant comorbidities.
Rahul Mittal, Nathanael Camick, Nathanael Camick, Joana R. N. Lemos, Khemraj Hirani   +4 more
doaj   +2 more sources

Gene-environment interaction analysis of school quality and educational inequality [PDF]

npj Science of Learning
We study to what extent schools increase or decrease environmental and genetic influences on educational performance. Building on behavioral genetics literature on gene-environment interactions and sociological literature on the compensating and ...
Kim Stienstra, Antonie Knigge, Ineke Maas   +2 more
doaj   +2 more sources

Random regression models for detection of gene by environment interaction [PDF]

Genetics Selection Evolution, 2007
Two random regression models, where the effect of a putative QTL was regressed on an environmental gradient, are described. The first model estimates the correlation between intercept and slope of the random regression, while the other model restricts ...
Meuwissen Theo HE, Ødegård Jørgen, Lillehammer Marie   +2 more
doaj   +2 more sources

Mito-SiPE is a sequence-independent and PCR-free mtDNA enrichment method for accurate ultra-deep mitochondrial sequencing

Communications Biology, 2022
Mito-SiPE is a mitochondrial DNA (mtDNA) enrichment method that can derive high-quality mtDNA for rare heteroplasmy analysis, without relying on PCR or probes.
Darren J. Walsh, David J. Bernard, Faith Pangilinan, Madison Esposito, Denise Harold, Anne Parle-McDermott, Lawrence C. Brody   +6 more
doaj   +1 more source

Gene-environment interaction in yeast gene expression. [PDF]

PLoS Biology, 2008
The effects of genetic variants on phenotypic traits often depend on environmental and physiological conditions, but such gene-environment interactions are poorly understood.
Erin N Smith, Leonid Kruglyak
doaj   +1 more source

Candidate gene-environment interactions [PDF]

Journal of Epidemiology & Community Health, 2010
International ...
Kauffmann, Francine, Nadif, Rachel
openaire   +7 more sources