Results 41 to 50 of about 11,702,420 (293)
Breast Cancer Research, 2023 Background Moderate to heavy alcohol consumption is associated with an increased risk of breast cancer. The etiologic role of genetic variation in genes involved in ethanol metabolism has not been established, with little information available among ...
Kristin L. Young +8 more
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Replication of Gene-by-psychosocial Stress Interaction Effects on Central Adiposity in a Korean Population [PDF]
Journal of Preventive Medicine and Public Health, 2016 Objectives Central obesity plays a major role in the development of many chronic diseases, including cardiovascular disease and cancer. Chronic stress may be involved in the pathophysiology of central obesity.
Hyun-Jin Kim +2 more
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The lipoprotein lipase S447X polymorphism and plasma lipids
Journal of Lipid Research, 2004 We studied 4,058 subjects from a representative sample of the Singapore population 1) to determine the association between the S447X polymorphism at the LPL locus and serum lipid concentration in Chinese, Malays, and Asian Indians living in Singapore and
J. Lee +6 more
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Gene-environment interactions in atherosclerosis
Molecular and Cellular Biochemistry, 1992 It is becoming clear that genetic and environmental factors can interact to varying degrees in a given individual. In some cases, genetically determined resistance to CAD (eg, genetic hyperalpha- or hypobetalipoproteinemia), or genetically determined susceptibility to CAD (eg, high Lp[a] levels) may not be significantly modulated by a prudent lifestyle.
openaire +4 more sources
Use of spermatozoal mRNA profiles to study gene-environment interactions in human germ cells
, 2009 Paternal exposure to genotoxic compounds is thought to contribute to diseases in their offspring. Therefore, it is of importance to develop biomarkers of male germ cell exposure to genotoxins.
Cemeli, E. +6 more
core +1 more source
IPRS: Leveraging Gene-Environment Interaction to Reconstruct Polygenic Risk Score
Frontiers in Genetics, 2022 Background: Polygenic risk score (PRS) is widely regarded as a predictor of genetic susceptibility to disease, applied to individuals to predict the risk of disease occurrence.
Yingdan Tang +6 more
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Gene-environment interactions and the response to exercise
International Journal of Experimental Pathology, 2000 Many of the symptoms of heart failure (breathlessness and fatigue) are not primarily due to reduced cardiac output, but relate to an impairment of peripheral muscle performance and metabolic efficiency. With regular training it is possible to increase skeletal muscle performance through improvements in muscle efficiency.
H, Montgomery, D, Brull
openaire +3 more sources
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
, 2017 Gene-environment interaction models identified by the GMDR method with adjustment for age and gender.
Chung-Feng Kao (104445) +5 more
core +1 more source
PLoS Genetics, 2016 How combinations of gene-environment interactions collectively give rise to genotype-environment interactions is not fully understood. To shed light on this problem, we genetically dissected an environment-specific poor growth phenotype in a cross of two
Takeshi Matsui, Ian M Ehrenreich
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