Results 41 to 50 of about 15,130,803 (334)

Information-theoretic gene-gene and gene-environment interaction analysis of quantitative traits

BMC Genomics, 2009
Background The purpose of this research was to develop a novel information theoretic method and an efficient algorithm for analyzing the gene-gene (GGI) and gene-environmental interactions (GEI) associated with quantitative traits (QT).
Liu Song, Sucheston Lara, Chanda Pritam, Zhang Aidong, Ramanathan Murali   +4 more
doaj   +1 more source

A Gene–Environment Interaction Between Smoking and Gene polymorphisms Provides a High Risk of Two Subgroups of Sarcoidosis

Scientific Reports, 2019
The influence and effect of cigarette smoking in sarcoidosis is unclear. Here, we evaluated gene-environment interaction between multiple genetic variants including HLA genes and smoking in sarcoidosis defined by two clinical phenotypes, Löfgren’s ...
Natalia V. Rivera, K. Patasova, S. Kullberg, L. Díaz-Gallo, T. Iseda, C. Bengtsson, L. Alfredsson, A. Eklund, I. Kockum, J. Grunewald, L. Padyukov   +10 more
semanticscholar   +1 more source

Gene‐environment interactions in childhood asthma revisited; expanding the interaction concept

Pediatric Allergy and Immunology, 2022
Investigation of gene‐environment interactions (GxE) may provide important insights into the gene regulatory framework in response to environmental factors of relevance for childhood asthma.
N. Hernandez-Pacheco, M. Kere, E. Mélen
semanticscholar   +1 more source

Gene–Environment Interactions on Growth Trajectories [PDF]

Genetic Epidemiology, 2012
It has been suggested that children with larger brains tend to perform better on IQ tests or cognitive function tests. Prenatal head growth and head growth in infancy are two crucial periods for subsequent intelligence. Studies have shown that environmental exposure to air pollutants during pregnancy is associated with fetal growth reduction ...
Wang, Shuang, Xiong, Wei, Ma, Weiping, Chanock, Stephen, Jedrychowski, Wieslaw, Wu, Rongling, Perera, Frederica P.   +6 more
openaire   +3 more sources

Influence of alcohol consumption and alcohol metabolism variants on breast cancer risk among Black women: results from the AMBER consortium

Breast Cancer Research, 2023
Background Moderate to heavy alcohol consumption is associated with an increased risk of breast cancer. The etiologic role of genetic variation in genes involved in ethanol metabolism has not been established, with little information available among ...
Kristin L. Young, Andrew F. Olshan, Kathryn Lunetta, Mariaelisa Graff, Lindsay A. Williams, Song Yao, Gary R. Zirpoli, Melissa Troester, Julie R. Palmer   +8 more
doaj   +1 more source

Gene-environment interaction study for BMI reveals interactions between genetic factors and physical activity, alcohol consumption and socioeconomic status

PLoS Genetics, 2017
Previous genome-wide association studies (GWAS) have identified hundreds of genetic loci to be associated with body mass index (BMI) and risk of obesity.
M. Rask-Andersen, T. Karlsson, W. Ek, Å. Johansson   +3 more
semanticscholar   +1 more source

The lipoprotein lipase S447X polymorphism and plasma lipids

Journal of Lipid Research, 2004
We studied 4,058 subjects from a representative sample of the Singapore population 1) to determine the association between the S447X polymorphism at the LPL locus and serum lipid concentration in Chinese, Malays, and Asian Indians living in Singapore and
J. Lee, C.S. Tan, K.S. Chia, C.E. Tan, S.K. Chew, J.M. Ordovas, E.S. Tai   +6 more
doaj   +1 more source

Replication of Gene-by-psychosocial Stress Interaction Effects on Central Adiposity in a Korean Population [PDF]

Journal of Preventive Medicine and Public Health, 2016
Objectives Central obesity plays a major role in the development of many chronic diseases, including cardiovascular disease and cancer. Chronic stress may be involved in the pathophysiology of central obesity.
Hyun-Jin Kim, Jin-Young Min, Kyoung-Bok Min   +2 more
doaj   +1 more source

Candidate Gene-Environment Interaction Research: Reflections and Recommendations

Perspectives on Psychological Science, 2015
Studying how genetic predispositions come together with environmental factors to contribute to complex behavioral outcomes has great potential for advancing the understanding of the development of psychopathology.
D. Dick, A. Agrawal, Matthew C. Keller, A. Adkins, F. Aliev, S. Monroe, J. Hewitt, K. Kendler, K. Sher   +8 more
semanticscholar   +1 more source

Gene-environment interaction models identified by the GMDR method with adjustment for age and gender.

, 2017
Gene-environment interaction models identified by the GMDR method with adjustment for age and gender.
Chung-Feng Kao (104445), Po-Hsiu Kuo (104448), Yu-Li Liu (175348), Shih-Jen Tsai (160992), Albert C. Yang (222158), Eugene Lin (759907)   +5 more
core   +1 more source