Results 31 to 40 of about 922,149 (303)
Myopia: Gene-environment Interaction
Annals of the Academy of Medicine Singapore, 2000 Introduction: Myopia has reached epidemic proportions in Japan, Hong Kong, Taiwan and Singapore. This review summarises the evidence for environmental and genetic factors as well as gene-environment interaction for myopia for both epidemiologic studies as well as animal models.
Yap, E. +5 more
openaire +2 more sources
Dependent negative life events and sleep quality: An examination of gene-environment interplay. [PDF]
, 2011 Objectives: Negative life events are associated with sleep disturbances. Further understanding of these associations is beneficial as sleep disturbances are common.
Eley, Thalia C. +11 more
core +1 more source
Structured gene‐environment interaction analysis [PDF]
Biometrics, 2019 AbstractFor the etiology, progression, and treatment of complex diseases, gene‐environment (G‐E) interactions have important implications beyond the main G and E effects. G‐E interaction analysis can be more challenging with higher dimensionality and need for accommodating the “main effects, interactions” hierarchy.
Mengyun Wu, Qingzhao Zhang, Shuangge Ma
openaire +4 more sources
Artificial neural networks modeling gene-environment interaction
BMC Genetics, 2012 Background Gene-environment interactions play an important role in the etiological pathway of complex diseases. An appropriate statistical method for handling a wide variety of complex situations involving interactions between variables is still lacking,
Günther Frauke +2 more
doaj +1 more source
Gene–Environment Interactions on Growth Trajectories [PDF]
Genetic Epidemiology, 2012 It has been suggested that children with larger brains tend to perform better on IQ tests or cognitive function tests. Prenatal head growth and head growth in infancy are two crucial periods for subsequent intelligence. Studies have shown that environmental exposure to air pollutants during pregnancy is associated with fetal growth reduction ...
Wang, Shuang +6 more
openaire +3 more sources
Finding gene-environment interactions for phobias [PDF]
European Archives of Psychiatry and Clinical Neuroscience, 2008 Phobias are common disorders causing a great deal of suffering. Studies of gene-environment interaction (G x E) have revealed much about the complex processes underlying the development of various psychiatric disorders but have told us little about phobias.
Gregory, Alice M +2 more
openaire +4 more sources
Genetic interactions affecting human gene expression identified by variance association mapping
eLife, 2014 Non-additive interaction between genetic variants, or epistasis, is a possible explanation for the gap between heritability of complex traits and the variation explained by identified genetic loci.
Andrew Anand Brown +9 more
doaj +1 more source
Breast Cancer Research, 2023 Background Moderate to heavy alcohol consumption is associated with an increased risk of breast cancer. The etiologic role of genetic variation in genes involved in ethanol metabolism has not been established, with little information available among ...
Kristin L. Young +8 more
doaj +1 more source
Information-theoretic gene-gene and gene-environment interaction analysis of quantitative traits
BMC Genomics, 2009 Background The purpose of this research was to develop a novel information theoretic method and an efficient algorithm for analyzing the gene-gene (GGI) and gene-environmental interactions (GEI) associated with quantitative traits (QT).
Liu Song +4 more
doaj +1 more source
Replication of Gene-by-psychosocial Stress Interaction Effects on Central Adiposity in a Korean Population [PDF]
Journal of Preventive Medicine and Public Health, 2016 Objectives Central obesity plays a major role in the development of many chronic diseases, including cardiovascular disease and cancer. Chronic stress may be involved in the pathophysiology of central obesity.
Hyun-Jin Kim +2 more
doaj +1 more source