Results 11 to 20 of about 922,149 (303)

Gene–gene and gene-environment interactions on cord blood total IgE in Chinese Han children

open access: yesAllergy, Asthma & Clinical Immunology, 2021
Background IL13, IL4, IL4RA, FCER1B and ADRB2 are susceptible genes of asthma and atopy. Our previous study has found gene–gene interactions on asthma between these genes in Chinese Han children. Whether the interactions begin in fetal stage, and whether
Li Hua   +18 more
doaj   +1 more source

Gene-environment interaction in psychopathologies: stress-related genetic and epigenetic influences [PDF]

open access: yesKlinik Psikoloji Dergisi, 2021
It has long been known that stressful life events are related to various psychological problems. The relationship between stress and psychiatric disorders has been further recognized due to reports of studies investigating interactions between biological
Esra Zıvralı Yarar
doaj   +1 more source

Mutual information for testing gene-environment interaction. [PDF]

open access: yesPLoS ONE, 2009
Despite current enthusiasm for investigation of gene-gene interactions and gene-environment interactions, the essential issue of how to define and detect gene-environment interactions remains unresolved.
Xuesen Wu, Li Jin, Momiao Xiong
doaj   +1 more source

Gene-environment interaction in molar-incisor hypomineralization.

open access: yesPLoS ONE, 2021
Molar incisor hypomineralization (MIH) is an enamel condition characterized by lesions ranging in color from white to brown which present rapid caries progression, and mainly affects permanent first molars and incisors. These enamel defects usually occur
Mariana Bezamat   +22 more
doaj   +1 more source

Gene–environment interactions in asthma [PDF]

open access: yesOccupational and Environmental Medicine, 2006
Asthma is a complex disease with a diverse genetic and environmental component.1 Asthma shows a high level of phenotypic heterogeneity characterised by obstruction of the airways of the lung and is related with atopy, bronchial hyperresponsiveness (BHR), and increased IgE levels.
F, Castro-Giner   +3 more
openaire   +2 more sources

Gene environment interactions in asthma [PDF]

open access: yesArchives of Disease in Childhood, 2007
The underlying pathogenesis of asthma, one of the most common chronic diseases of childhood, is not fully understood. There is a well-documented heritable component to this disease and environmental factors associated with a Westernised lifestyle have also been implicated; recent studies suggest gene-environment interactions are important in the ...
S, McLeish, S W, Turner
openaire   +2 more sources

Efficient gene–environment interaction testing through bootstrap aggregating

open access: yesScientific Reports, 2023
Gene–environment (GxE) interactions are an important and sophisticated component in the manifestation of complex phenotypes. Simple univariate tests lack statistical power due to the need for multiple testing adjustment and not incorporating potential ...
Michael Lau   +3 more
doaj   +1 more source

How ambient temperature affects the heading date of foxtail millet (Setaria italica)

open access: yesFrontiers in Plant Science, 2023
Foxtail millet (Setaria italica), a short-day plant, is one of the important crops for food security encountering climate change, particularly in regions where it is a staple food.
Ya-Chen Huang   +8 more
doaj   +1 more source

Signatures of adaptation in myopia-related genes on the sunlight exposure hypothesis

open access: yesJournal of Physiological Anthropology, 2023
Background Myopia is a common eye disorder that results from gene-environment interactions. The prevalence of myopia varies across populations, and exposure to bright sunlight may prevent its development.
Tian Xia, Kazuhiro Nakayama
doaj   +1 more source

A novel approach to simulate gene-environment interactions in complex diseases [PDF]

open access: yes, 2010
Background: Complex diseases are multifactorial traits caused by both genetic and environmental factors. They represent the major part of human diseases and include those with largest prevalence and mortality (cancer, heart disease, obesity, etc ...
Amato, Roberto   +24 more
core   +1 more source

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