Results 11 to 20 of about 15,130,803 (334)

Gene-Environment Dependence Creates Spurious Gene-Environment Interaction [PDF]

open access: yesThe American Journal of Human Genetics, 2014
Gene-environment interactions have the potential to shed light on biological processes leading to disease and to improve the accuracy of epidemiological risk models. However, relatively few such interactions have yet been confirmed.
F. Dudbridge, O. Fletcher
semanticscholar   +5 more sources

Gene-environment interaction in yeast gene expression. [PDF]

open access: yesPLoS Biology, 2008
The effects of genetic variants on phenotypic traits often depend on environmental and physiological conditions, but such gene-environment interactions are poorly understood.
Erin N Smith, Leonid Kruglyak
doaj   +3 more sources

Structured gene-environment interaction analysis [PDF]

open access: yesBiometrics, 2018
For the etiology, progression, and treatment of complex diseases, gene‐environment (G‐E) interactions have important implications beyond the main G and E effects.
Meng-Yun Wu   +2 more
semanticscholar   +6 more sources

Gene-environment interaction: A genetic-epidemiological approach [PDF]

open access: yesJournal of Medical Biochemistry, 2010
Classical epidemiology addresses the distribution and determinants of diseases in populations, and the factors associated with disease causation, with the aim of preventing disease. Both genetic and environmental factors may contribute to susceptibility,
Pekmezović Tatjana
doaj   +2 more sources

A flexible Bayesian model for studying gene-environment interaction. [PDF]

open access: yesPLoS Genetics, 2012
An important follow-up step after genetic markers are found to be associated with a disease outcome is a more detailed analysis investigating how the implicated gene or chromosomal region and an established environment risk factor interact to influence ...
Kai Yu   +6 more
doaj   +3 more sources

Mito-SiPE is a sequence-independent and PCR-free mtDNA enrichment method for accurate ultra-deep mitochondrial sequencing

open access: yesCommunications Biology, 2022
Mito-SiPE is a mitochondrial DNA (mtDNA) enrichment method that can derive high-quality mtDNA for rare heteroplasmy analysis, without relying on PCR or probes.
Darren J. Walsh   +6 more
doaj   +1 more source

Gene–gene and gene-environment interactions on cord blood total IgE in Chinese Han children

open access: yesAllergy, Asthma & Clinical Immunology, 2021
Background IL13, IL4, IL4RA, FCER1B and ADRB2 are susceptible genes of asthma and atopy. Our previous study has found gene–gene interactions on asthma between these genes in Chinese Han children. Whether the interactions begin in fetal stage, and whether
Li Hua   +18 more
doaj   +1 more source

Mutual information for testing gene-environment interaction. [PDF]

open access: yesPLoS ONE, 2009
Despite current enthusiasm for investigation of gene-gene interactions and gene-environment interactions, the essential issue of how to define and detect gene-environment interactions remains unresolved.
Xuesen Wu, Li Jin, Momiao Xiong
doaj   +1 more source

Gene-environment interaction in psychopathologies: stress-related genetic and epigenetic influences [PDF]

open access: yesKlinik Psikoloji Dergisi, 2021
It has long been known that stressful life events are related to various psychological problems. The relationship between stress and psychiatric disorders has been further recognized due to reports of studies investigating interactions between biological
Esra Zıvralı Yarar
doaj   +1 more source

Gene-environment interaction and obesity [PDF]

open access: yesNutrition Reviews, 2008
The epidemic of obesity has become a major public health problem. Common-form obesity is underpinned by both environmental and genetic factors. Epidemiological studies have documented that increased intakes of energy and reduced consumption of high-fiber foods, as well as sedentary lifestyle, were among the major driving forces for the epidemic of ...
Lu, Qi, Young Ae, Cho
openaire   +2 more sources

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