Results 51 to 60 of about 15,130,803 (334)
Inference of gene-environment interaction from heterogeneous case-parent trios
Frontiers in Genetics, 2023 Introduction: In genetic epidemiology, log-linear models of population risk may be used to study the effect of genotypes and exposures on the relative risk of a disease.
Pulindu Ratnasekera +2 more
doaj +1 more source
Comparison of weighting approaches for genetic risk scores in gene-environment interaction studies
BMC Genetics, 2017 BackgroundWeighted genetic risk scores (GRS), defined as weighted sums of risk alleles of single nucleotide polymorphisms (SNPs), are statistically powerful for detection gene-environment (GxE) interactions. To assign weights, the gold standard is to use
Anke Hüls +5 more
semanticscholar +1 more source
Gene × environment interaction in major depressive disorder
World Journal of Clinical Cases, 2021 Major depressive disorder (MDD) is a multifactorial disorder, where multiple susceptibility genes interact with environmental factors, predisposing individuals to the development of the illness.
Mingzhe Zhao, Xusheng Song, Jing-Song Ma
semanticscholar +1 more source
Gene-environment interactions in atherosclerosis
Molecular and Cellular Biochemistry, 1992 It is becoming clear that genetic and environmental factors can interact to varying degrees in a given individual. In some cases, genetically determined resistance to CAD (eg, genetic hyperalpha- or hypobetalipoproteinemia), or genetically determined susceptibility to CAD (eg, high Lp[a] levels) may not be significantly modulated by a prudent lifestyle.
openaire +4 more sources
Summary of gene-environment interaction results.
, 2013 Summary of gene-environment interaction results.
Yungling Leo Lee (176573) +5 more
core +1 more source
Gene-environment interactions and the response to exercise
International Journal of Experimental Pathology, 2000 Many of the symptoms of heart failure (breathlessness and fatigue) are not primarily due to reduced cardiac output, but relate to an impairment of peripheral muscle performance and metabolic efficiency. With regular training it is possible to increase skeletal muscle performance through improvements in muscle efficiency.
H, Montgomery, D, Brull
openaire +3 more sources
MDR analysis of gene-environment interaction.
, 2013 MDR analysis of gene-environment interaction.
Jia Su (128774) +8 more
core +1 more source
Dependent negative life events and sleep quality: An examination of gene-environment interplay. [PDF]
, 2011 Objectives: Negative life events are associated with sleep disturbances. Further understanding of these associations is beneficial as sleep disturbances are common.
Eley, Thalia C. +11 more
core +1 more source
PLoS Genetics, 2016 How combinations of gene-environment interactions collectively give rise to genotype-environment interactions is not fully understood. To shed light on this problem, we genetically dissected an environment-specific poor growth phenotype in a cross of two
Takeshi Matsui, Ian M Ehrenreich
doaj +1 more source
Gene–environment interaction and risk of breast cancer
British Journal of Cancer, 2016 Hereditary, genetic factors as well as lifestyle and environmental factors, for example, parity and body mass index, predict breast cancer development.
A. Rudolph, J. Chang-Claude, M. Schmidt
semanticscholar +1 more source