Results 11 to 20 of about 1,095,697 (331)

Gene-environment interaction in molar-incisor hypomineralization.

open access: yesPLoS ONE, 2021
Molar incisor hypomineralization (MIH) is an enamel condition characterized by lesions ranging in color from white to brown which present rapid caries progression, and mainly affects permanent first molars and incisors. These enamel defects usually occur
Mariana Bezamat   +22 more
doaj   +1 more source

Mutual information for testing gene-environment interaction. [PDF]

open access: yesPLoS ONE, 2009
Despite current enthusiasm for investigation of gene-gene interactions and gene-environment interactions, the essential issue of how to define and detect gene-environment interactions remains unresolved.
Xuesen Wu, Li Jin, Momiao Xiong
doaj   +1 more source

Candidate gene-environment interactions [PDF]

open access: yesJournal of Epidemiology & Community Health, 2010
One limitation of interdisciplinarity is the misunderstanding regarding specific words and concepts from one discipline to the other.1 One way to circumvent this aspect is to incorporate the vocabulary of other disciplines when it corresponds to the appropriate concept.
Kauffmann, Francine, Nadif, Rachel
openaire   +4 more sources

Effects of Thyroxine Exposure on Osteogenesis in Mouse Calvarial Pre-Osteoblasts [PDF]

open access: yes, 2013
The incidence of craniosynostosis is one in every 1,800-2500 births. The gene-environment model proposes that if a genetic predisposition is coupled with environmental exposures, the effects can be multiplicative resulting in severely abnormal phenotypes.
A Mansukhani   +58 more
core   +13 more sources

How ambient temperature affects the heading date of foxtail millet (Setaria italica)

open access: yesFrontiers in Plant Science, 2023
Foxtail millet (Setaria italica), a short-day plant, is one of the important crops for food security encountering climate change, particularly in regions where it is a staple food.
Ya-Chen Huang   +8 more
doaj   +1 more source

Signatures of adaptation in myopia-related genes on the sunlight exposure hypothesis

open access: yesJournal of Physiological Anthropology, 2023
Background Myopia is a common eye disorder that results from gene-environment interactions. The prevalence of myopia varies across populations, and exposure to bright sunlight may prevent its development.
Tian Xia, Kazuhiro Nakayama
doaj   +1 more source

Regulation of Pancreatic β-Cell Mass by Gene-Environment Interaction [PDF]

open access: yesDiabetes & Metabolism Journal, 2022
The main pathogenic mechanism of diabetes consists of an increase in insulin resistance and a decrease in insulin secretion from pancreatic β-cells. The number of diabetic patients has been increasing dramatically worldwide, especially in Asian people ...
Shun-ichiro Asahara   +2 more
doaj   +1 more source

Bayesian semiparametric analysis for two-phase studies of gene-environment interaction [PDF]

open access: yes, 2013
The two-phase sampling design is a cost-efficient way of collecting expensive covariate information on a judiciously selected subsample. It is natural to apply such a strategy for collecting genetic data in a subsample enriched for exposure to ...
Ahn, Jaeil   +3 more
core   +1 more source

Simulating gene-gene and gene-environment interactions in complex diseases: Gene-Environment iNteraction Simulator 2

open access: yesBMC Bioinformatics, 2012
Background The analysis of complex diseases is an important problem in human genetics. Because multifactoriality is expected to play a pivotal role, many studies are currently focused on collecting information on the genetic and environmental factors ...
Pinelli Michele   +4 more
doaj   +1 more source

The impact of imprecisely measured covariates on estimating gene-environment interactions [PDF]

open access: yes, 2006
BACKGROUND The effects of measurement error in epidemiological exposures and confounders on estimated effects of exposure are well described, but the effects on estimates for gene-environment interactions has received rather less attention.
Cade, J.E.   +2 more
core   +2 more sources

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