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Structured gene‐environment interaction analysis [PDF]
For the etiology, progression, and treatment of complex diseases, gene‐environment (G‐E) interactions have important implications beyond the main G and E effects.
Mengyun Wu, Qingzhao Zhang, Shuangge Ma
semanticscholar +6 more sources
Gene-environment interaction in yeast gene expression. [PDF]
The effects of genetic variants on phenotypic traits often depend on environmental and physiological conditions, but such gene-environment interactions are poorly understood.
Erin N Smith, Leonid Kruglyak
doaj +1 more source
Gene–gene and gene-environment interactions on cord blood total IgE in Chinese Han children
Background IL13, IL4, IL4RA, FCER1B and ADRB2 are susceptible genes of asthma and atopy. Our previous study has found gene–gene interactions on asthma between these genes in Chinese Han children. Whether the interactions begin in fetal stage, and whether
Li Hua+18 more
doaj +1 more source
Mutual information for testing gene-environment interaction. [PDF]
Despite current enthusiasm for investigation of gene-gene interactions and gene-environment interactions, the essential issue of how to define and detect gene-environment interactions remains unresolved.
Xuesen Wu, Li Jin, Momiao Xiong
doaj +1 more source
GEM: scalable and flexible gene–environment interaction analysis in millions of samples
Gene-environment interaction (GEI) studies are a general framework that can be used to identify genetic variants that modify environmental, physiological, lifestyle, or treatment effects, as well as those contributing to age, sex, racial or ethnic ...
K. Westerman+9 more
semanticscholar +1 more source
Candidate gene-environment interactions [PDF]
One limitation of interdisciplinarity is the misunderstanding regarding specific words and concepts from one discipline to the other.1 One way to circumvent this aspect is to incorporate the vocabulary of other disciplines when it corresponds to the appropriate concept.
Kauffmann, Francine, Nadif, Rachel
openaire +5 more sources
Gene-environment interaction in molar-incisor hypomineralization.
Molar incisor hypomineralization (MIH) is an enamel condition characterized by lesions ranging in color from white to brown which present rapid caries progression, and mainly affects permanent first molars and incisors. These enamel defects usually occur
Mariana Bezamat+22 more
doaj +1 more source
How ambient temperature affects the heading date of foxtail millet (Setaria italica)
Foxtail millet (Setaria italica), a short-day plant, is one of the important crops for food security encountering climate change, particularly in regions where it is a staple food.
Ya-Chen Huang+8 more
doaj +1 more source
Signatures of adaptation in myopia-related genes on the sunlight exposure hypothesis
Background Myopia is a common eye disorder that results from gene-environment interactions. The prevalence of myopia varies across populations, and exposure to bright sunlight may prevent its development.
Tian Xia, Kazuhiro Nakayama
doaj +1 more source
Regulation of Pancreatic β-Cell Mass by Gene-Environment Interaction [PDF]
The main pathogenic mechanism of diabetes consists of an increase in insulin resistance and a decrease in insulin secretion from pancreatic β-cells. The number of diabetic patients has been increasing dramatically worldwide, especially in Asian people ...
Shun-ichiro Asahara+2 more
doaj +1 more source