Results 11 to 20 of about 1,150,120 (282)

Gene–gene and gene-environment interactions on cord blood total IgE in Chinese Han children

open access: yesAllergy, Asthma & Clinical Immunology, 2021
Background IL13, IL4, IL4RA, FCER1B and ADRB2 are susceptible genes of asthma and atopy. Our previous study has found gene–gene interactions on asthma between these genes in Chinese Han children. Whether the interactions begin in fetal stage, and whether
Li Hua   +18 more
doaj   +1 more source

Gene-environment interaction in psychopathologies: stress-related genetic and epigenetic influences [PDF]

open access: yesKlinik Psikoloji Dergisi, 2021
It has long been known that stressful life events are related to various psychological problems. The relationship between stress and psychiatric disorders has been further recognized due to reports of studies investigating interactions between biological
Esra Zıvralı Yarar
doaj   +1 more source

Mutual information for testing gene-environment interaction. [PDF]

open access: yesPLoS ONE, 2009
Despite current enthusiasm for investigation of gene-gene interactions and gene-environment interactions, the essential issue of how to define and detect gene-environment interactions remains unresolved.
Xuesen Wu, Li Jin, Momiao Xiong
doaj   +1 more source

Gene-environment interaction in molar-incisor hypomineralization.

open access: yesPLoS ONE, 2021
Molar incisor hypomineralization (MIH) is an enamel condition characterized by lesions ranging in color from white to brown which present rapid caries progression, and mainly affects permanent first molars and incisors. These enamel defects usually occur
Mariana Bezamat   +22 more
doaj   +1 more source

How ambient temperature affects the heading date of foxtail millet (Setaria italica)

open access: yesFrontiers in Plant Science, 2023
Foxtail millet (Setaria italica), a short-day plant, is one of the important crops for food security encountering climate change, particularly in regions where it is a staple food.
Ya-Chen Huang   +8 more
doaj   +1 more source

Signatures of adaptation in myopia-related genes on the sunlight exposure hypothesis

open access: yesJournal of Physiological Anthropology, 2023
Background Myopia is a common eye disorder that results from gene-environment interactions. The prevalence of myopia varies across populations, and exposure to bright sunlight may prevent its development.
Tian Xia, Kazuhiro Nakayama
doaj   +1 more source

Bayesian semiparametric analysis for two-phase studies of gene-environment interaction [PDF]

open access: yes, 2013
The two-phase sampling design is a cost-efficient way of collecting expensive covariate information on a judiciously selected subsample. It is natural to apply such a strategy for collecting genetic data in a subsample enriched for exposure to ...
Ahn, Jaeil   +3 more
core   +1 more source

Regulation of Pancreatic β-Cell Mass by Gene-Environment Interaction [PDF]

open access: yesDiabetes & Metabolism Journal, 2022
The main pathogenic mechanism of diabetes consists of an increase in insulin resistance and a decrease in insulin secretion from pancreatic β-cells. The number of diabetic patients has been increasing dramatically worldwide, especially in Asian people ...
Shun-ichiro Asahara   +2 more
doaj   +1 more source

Simulating gene-gene and gene-environment interactions in complex diseases: Gene-Environment iNteraction Simulator 2

open access: yesBMC Bioinformatics, 2012
Background The analysis of complex diseases is an important problem in human genetics. Because multifactoriality is expected to play a pivotal role, many studies are currently focused on collecting information on the genetic and environmental factors ...
Pinelli Michele   +4 more
doaj   +1 more source

The impact of imprecisely measured covariates on estimating gene-environment interactions [PDF]

open access: yes, 2006
BACKGROUND The effects of measurement error in epidemiological exposures and confounders on estimated effects of exposure are well described, but the effects on estimates for gene-environment interactions has received rather less attention.
Cade, J.E.   +2 more
core   +2 more sources

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