Results 41 to 50 of about 2,615,001 (338)
The fields of data mining, computational biology, and statistics have been combined to form the massive research area of bioinformatics. In the areas of genetics, education, and healthcare, bioinformatics integrates the tools available in different ...
Md. Abul Basar +5 more
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Gene-centric gene-gene interaction: A model-based kernel machine method
Much of the natural variation for a complex trait can be explained by variation in DNA sequence levels. As part of sequence variation, gene-gene interaction has been ubiquitously observed in nature, where its role in shaping the development of an ...
Cui, Yuehua, Li, Shaoyu
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Gene transcription analysis during interaction between potato and Ralstonia solanacearum [PDF]
Bacterial wilt (BW) caused by Ralstonia solanacearum (Rs) is an important quarantine disease that spreads worldwide and infects hundreds of plant species. The BW defense response of potato is a complicated continuous process, which involves transcription
Huang, S.W. +7 more
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FASTCHI: AN EFFICIENT ALGORITHM FOR ANALYZING GENE-GENE INTERACTIONS [PDF]
Recent advances in high-throughput genotyping have inspired increasing research interests in genome-wide association study for diseases. To understand underlying biological mechanisms of many diseases, we need to consider simultaneously the genetic effects across multiple loci.
Xiang Zhang 0001, Fei Zou, Wei Wang 0010
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Efficient regularized isotonic regression with application to gene--gene interaction search
Isotonic regression is a nonparametric approach for fitting monotonic models to data that has been widely studied from both theoretical and practical perspectives.
Luss, Ronny +2 more
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Statistical Indicators of Collective Behavior and Functional Clusters in Gene Networks of Yeast [PDF]
We analyze gene expression time-series data of yeast S. cerevisiae measured along two full cell-cycles. We quantify these data by using q-exponentials, gene expression ranking and a temporal mean-variance analysis.
Tadic, Bosiljka +3 more
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Machine Learning for Detecting Gene-Gene Interactions [PDF]
Complex interactions among genes and environmental factors are known to play a role in common human disease aetiology. There is a growing body of evidence to suggest that complex interactions are 'the norm' and, rather than amounting to a small perturbation to classical Mendelian genetics, interactions may be the predominant effect.
Brett A, McKinney +3 more
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Background: Vascular endothelial growth factor A (VEGFA) and brain-derived neurotrophic factor (BDNF), the most abundant and widely expressed neurotrophic factors in the brain, are believed to play an important rôle in depression and anxiety.
Eugene Lin +4 more
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Diverged and Active Partitiviruses in Lichen
The lichen is a microbial consortium that mainly consists of fungi and either algae (Viridiplantae) or cyanobacteria. This structure also contains other bacteria, fungi, and viruses.
Syun-ichi Urayama +11 more
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Identification of transcriptional regulatory networks specific to pilocytic astrocytoma. [PDF]
BackgroundPilocytic Astrocytomas (PAs) are common low-grade central nervous system malignancies for which few recurrent and specific genetic alterations have been identified.
Deshmukh, Hrishikesh +8 more
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