Results 41 to 50 of about 7,758,263 (304)
FASTCHI: AN EFFICIENT ALGORITHM FOR ANALYZING GENE-GENE INTERACTIONS [PDF]
Biocomputing 2009, 2008 Recent advances in high-throughput genotyping have inspired increasing research interests in genome-wide association study for diseases. To understand underlying biological mechanisms of many diseases, we need to consider simultaneously the genetic effects across multiple loci.
Xiang Zhang 0001, Fei Zou, Wei Wang 0010
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, 2019 Gene-gene interaction: COLEC11 and MASP2 genotypes frequencies in patients with chronic CD and healthy controls.
Iara J. Messias-Reason (535489) +7 more
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Pharmacogenomics of Hypertension and Preeclampsia: Focus on Gene–Gene Interactions [PDF]
Frontiers in Pharmacology, 2018 Hypertension is a leading cause of cardiovascular mortality, but only about half of patients on antihypertensive therapy achieve blood pressure control. Preeclampsia is defined as pregnancy-induced hypertension and proteinuria, and is associated with increased maternal and perinatal mortality and morbidity.
Marcelo R. Luizon +3 more
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Therapeutic Apheresis and Dialysis, EarlyView.ABSTRACT Introduction Hyperlipidemia is a major risk factor for atherosclerotic cardiovascular disease (ASCVD). Although statins are the cornerstone of lipid‐lowering therapy, their use may be limited in some patients by adverse effects. This study evaluated the possible impact of non‐drug treatment using double‐filtration plasmapheresis (DFPP) on CD14+
Yun Cheng +3 more
wiley +1 more source
Taiwanese Journal of Psychiatry, 2019 Background: Vascular endothelial growth factor A (VEGFA) and brain-derived neurotrophic factor (BDNF), the most abundant and widely expressed neurotrophic factors in the brain, are believed to play an important rôle in depression and anxiety.
Eugene Lin +4 more
doaj +1 more source
Diverged and Active Partitiviruses in Lichen
Frontiers in Microbiology, 2020 The lichen is a microbial consortium that mainly consists of fungi and either algae (Viridiplantae) or cyanobacteria. This structure also contains other bacteria, fungi, and viruses.
Syun-ichi Urayama +11 more
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Gene-disease heterogeneous network.
, 2019 The top network is gene-gene interaction network, the bottom network is disease-disease similarity network and they are connected by gene-disease relationship (dashed grey lines).
Yidong Chen (11610) +6 more
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Machine Learning for Detecting Gene-Gene Interactions [PDF]
Applied Bioinformatics, 2006 Complex interactions among genes and environmental factors are known to play a role in common human disease aetiology. There is a growing body of evidence to suggest that complex interactions are 'the norm' and, rather than amounting to a small perturbation to classical Mendelian genetics, interactions may be the predominant effect.
Brett A, McKinney +3 more
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FEBS Letters, EarlyView.Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi +5 more
wiley +1 more source
Genetic interactions affecting human gene expression identified by variance association mapping
eLife, 2014 Non-additive interaction between genetic variants, or epistasis, is a possible explanation for the gap between heritability of complex traits and the variation explained by identified genetic loci.
Andrew Anand Brown +9 more
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