Results 121 to 130 of about 16,521,028 (347)
A Cre‐dependent lentiviral vector for neuron subtype‐specific expression of large proteins
We designed a versatile and modular lentivector comprising a Cre‐dependent switch and self‐cleaving 2A peptide and tested it for co‐expression of GFP and a 2.8 kb gene of interest (GOI) in mouse cortical parvalbumin (PV+) interneurons and midbrain dopamine (TH+) neurons.
Weixuan Xue +6 more
wiley +1 more source
The IQ‐compete assay for measuring mitochondrial protein import efficiencies in living yeast cells
The efficiency of mitochondrial protein import depends on the properties of the newly synthesized precursor proteins. The Import and de‐Quenching Competition (IQ‐compete) assay is a novel method to monitor the import efficiency of different proteins by fluorescence in living yeast cells.
Yasmin Hoffman +3 more
wiley +1 more source
A rare intronic c.2654+1G>A mutation in CSF1R-microglial encephalopathy: a case report
ObjectiveWe report a case of CSF1R-microglial encephalopathy associated with a rare intronic c.2654 + 1G>A mutation, featuring negative diffusion-weighted imaging (DWI) findings and a cerebrospinal fluid (CSF) biomarker profile indicative of Alzheimer’
HongYan Wu +4 more
doaj +1 more source
Quorum-sensing autoinducer molecules produced by members of a multispecies biofilm promote horizontal gene transfer to Vibrio cholerae [PDF]
Elena S. Antonova, Brian K. Hammer
openalex +1 more source
Includes: Cynthia , by Grace Ferguson and Parodies , by Gene Smith and Grace ...
Ferguson, Grace, Smith, Gene
core +1 more source
Anaplastic thyroid cancer (ATC) lacks iodide uptake ability due to MAPK activation increasing the expression of the histone methyltransferase EZH2, which represses thyroid differentiation genes (TDGs) such as the sodium iodide symporter (NIS). Dual inhibition of MAPK (U0126) and EZH2 (EPZ6438/Tazemetostat) reverses this mechanism, thus restoring TDG ...
Diego Claro de Mello +6 more
wiley +1 more source
Papillon-Lefevre syndrome (PLS) is a rare autosomal recessive disorder characterized by severe early-onset periodontal destruction involving both the deciduous and permanent dentition and skin lesions of palmoplantar hyperkeratosis. Recently it was found
L. Izakovičová Hollá +3 more
doaj
Ziwei Du,1 Hepeng Wang,1 Yang Gao,1 Shumao Zheng,1 Xiaoli Kou,1 Guoqiang Sun,1 Jinxian Song,2 Jingfei Dong,3 Genhui Wang4 1Department of Dermatology, Hebei Academy of Traditional Chinese Medicine, Shijiazhuang, Hebei, 050031, People’s Republic of China ...
Du Z +8 more
doaj
By dawn or dusk—how circadian timing rewrites bacterial infection outcomes
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo +2 more
wiley +1 more source
Exome sequencing reveals a novel mutation for autosomal recessive non-syndromic mental retardation in the TECR gene on chromosome 19p13 [PDF]
Minal Çalışkan +14 more
openalex +1 more source

