Results 151 to 160 of about 6,617,997 (307)

Relating transcriptomics to protein abundance reveals self-driven versus interactor-driven proteins. [PDF]

Protein Sci
Arnaout L, Helms V, Papazian A.
europepmc   +1 more source

Isolation and functional analysis of the promoter of the amphioxus Hsp70a gene

, 2012
National High Technology Research and Development Program of China [2008AA092602]; National Natural Science Foundation of China [30830023, 31071110]Amphioxus is a promising laboratorial model animal for studying the evolutionary and developmental ...
Chen, Xinhua, Li, Dingliang, Wang, Kunru, Li, Guang, Li, Weiye, 李光, Liu, Xin, Wang, Yiquan, 王义权   +8 more
core  

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Exploring the Mechanism of Zhigancao Decoction in the Treatment of Chronic Heart Failure via Modulation of Oxidative Stress. [PDF]

Rapid Commun Mass Spectrom
Luo Z, Huang Y, Tian Y, Huang S, Li F.
europepmc   +1 more source

Letter to George, from Gene, Burnett, Wisconsin, May 18, 1862

An item in the George Woodard and Gene Smith letters ...
Woodard, George T., -1864, Smith, Gene E.   +1 more
core  

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

Molecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera, Laura Vela‐Martín, Pablo Fernández‐Navarro, José Luis López‐Lorenzo, Javier Cornago, Pilar Llamas, Eduardo Pérez‐Gómez, José Luis Marín‐Rubio, Manuel Fresno, Javier Santos, José Fernández‐Piqueras, María Villa‐Morales   +11 more
wiley   +1 more source

Detection of Myoglobin Gene Polymorphism Associated With Pigeons' Growth Traits. [PDF]

Anim Genet
Liao Z, Lin S, Ali S, Lin J, Wu Y, Peng Q, Peng S, Li L, Gu L, Zhang L.   +9 more
europepmc   +1 more source

Letter to George, from Gene, Burnett, Wisconsin, January 26, 1862

An item in the George Woodard and Gene Smith letters ...
Woodard, George T., -1864, Smith, Gene E.   +1 more
core  

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Effect of Green-Synthesized Silver Nanoparticles From Nepeta pogonosperma and Astrodaucus persicus on the Reduction of Bap Gene Expression in Strong Biofilm-Producing Acinetobacter baumannii Clinical Isolates. [PDF]

Microbiologyopen
Kakavan M, Gholami M, Ahanjan M, Ebrahimzadeh MA, Hossein Nataj A, Mousavi T, Goli HR.   +6 more
europepmc   +1 more source