Results 251 to 260 of about 16,521,028 (347)

Automated Identification of Medically Important Bacteria by 16S rRNA Gene Sequencing Using a Novel Comprehensive Database, 16SpathDB [PDF]

, 2011
Patrick C. Y. Woo, Jade L. L. Teng, Juilian M. Y. Yeung, Herman Tse, Susanna K. P. Lau, Kwok‐Yung Yuen   +5 more
openalex   +1 more source

Tumor and germline testing with next generation sequencing in epithelial ovarian cancer: a prospective paired comparison using an 18‐gene panel

Molecular Oncology, EarlyView.
Genetic testing in epithelial ovarian cancer includes both germline and tumor‐testing. This approach often duplicates resources. The current prospective study assessed the feasibility of tumor‐first multigene testing by comparing tumor tissue with germline testing of peripheral blood using an 18‐gene NGS panel in 106 patients.
Elisabeth Spenard, Cristina Mitric, Melanie Care, Tracy L. Stockley, Raymond H. Kim, Jeanna McCuaig, Blaise Clarke, Laura Ranich, Clare Sheen, Sarah E. Ferguson, Liat Hogen, Taymaa May, Marcus Q. Bernardini   +12 more
wiley   +1 more source

Toward an all-in-one recombinant adeno-associated virus vector for functionally ablating the prion gene using CRISPR-Cas technology. [PDF]

PLoS One
Verkuyl C, Belotserkovsky A, Zerbes T, Williams D, Krishnan MR, Zhu S, Grunnesjӧ S, Eid S, Zhang C, Zhao W, Xu L, Lin E, O'Shea T, Draper B, Jungman A, Most P, Schmitt-Ulms G.   +16 more
europepmc   +1 more source

Gene Selection for Cancer Classification using Support Vector Machines

Machine-mediated learning, 2002
Isabelle M Guyon, J. Weston, S. Barnhill, V. Vapnik   +3 more
semanticscholar   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source

Young KRAB-zinc finger gene clusters are highly dynamic incubators of ERV-driven genetic heterogeneity in mice. [PDF]

Nat Commun
Bruno M, Farhana SM, Mitra A, Costello K, Watkins-Chow DE, Logsdon GA, Gambogi CW, Dumont BL, Black BE, Keane TM, Ferguson-Smith AC, Dale RK, Macfarlan TS.   +12 more
europepmc   +1 more source

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

Molecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard, Sarmad Mehmood, Eva Boysen Fynboe Ebert, Peter Meldgaard, Anindya Dutta, Boe S. Sorensen   +5 more
wiley   +1 more source

Chinese guidance for the clinical application of adeno-associated virus vector-based gene therapy for hemophilia B (2025). [PDF]

Blood Sci
Xue F, Hu Y, Yang R, Sun J, Yang L, Wang X, Yu Z, Zhu T, Zhou H, Zhou Z, Yan Z, Du X, Zheng C, Liu W, Zhou R, Dai J, Yin J, Wang H, Tang LV, Chen S, Cheng H, Zhu M, Wang S, Song Y, Zhang P, Zhang L.   +25 more
europepmc   +1 more source

FOXP3 immunoregulatory gene variants are independent predictors of human papillomavirus infection and cervical cancer precursor lesions

, 2019
Fernando Cezar‐dos‐Santos, Rodolfo Sanches Ferreira, Nádia Calvo Martins Okuyama, Kleber Paiva Trugilo, Michelle Mota Sena, Érica Romão Pereira, Ana Paula Lombardi Pereira, Maria Angélica Ehara Watanabe, Karen Brajão de Oliveira   +8 more
openalex   +2 more sources

Survivin and Aurora Kinase A control cell fate decisions during mitosis

Molecular Oncology, EarlyView.
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir, Shalitha Wickrama Arachchige, Sally P. Wheatley   +2 more
wiley   +1 more source