Results 21 to 30 of about 9,577,131 (98)

Genetic effects on gene expression across human tissues

open access: yesNature, 2017
Characterization of the molecular function of the human genome and its variation across individuals is essential for identifying the cellular mechanisms that underlie human genetic traits and diseases.
François Andrew A. Stephane E. Joe R. Yuan Brian Pejman YoS Aguet Brown Castel Davis He Jo Mohammadi Park Pars   +324 more
semanticscholar   +1 more source

REVIGO Summarizes and Visualizes Long Lists of Gene Ontology Terms

open access: yesPLoS ONE, 2011
Outcomes of high-throughput biological experiments are typically interpreted by statistical testing for enriched gene functional categories defined by the Gene Ontology (GO).
F. Supek   +3 more
semanticscholar   +1 more source

MCScanX: a toolkit for detection and evolutionary analysis of gene synteny and collinearity

open access: yesNucleic Acids Research, 2012
MCScan is an algorithm able to scan multiple genomes or subgenomes in order to identify putative homologous chromosomal regions, and align these regions using genes as anchors.
Yupeng Wang   +11 more
semanticscholar   +1 more source

ClueGO: a Cytoscape plug-in to decipher functionally grouped gene ontology and pathway annotation networks

open access: yesBioinform., 2009
Summary: We have developed ClueGO, an easy to use Cytoscape plug-in that strongly improves biological interpretation of large lists of genes. ClueGO integrates Gene Ontology (GO) terms as well as KEGG/BioCarta pathways and creates a functionally ...
G. Bindea   +9 more
semanticscholar   +1 more source

Construction of Escherichia coli K-12 in-frame, single-gene knockout mutants: the Keio collection

open access: yesMolecular Systems Biology, 2006
We have systematically made a set of precisely defined, single‐gene deletions of all nonessential genes in Escherichia coli K‐12. Open‐reading frame coding regions were replaced with a kanamycin cassette flanked by FLP recognition target sites by using a
T. Baba   +9 more
semanticscholar   +1 more source

Prediction of complete gene structures in human genomic DNA.

open access: yesJournal of Molecular Biology, 1997
We introduce a general probabilistic model of the gene structure of human genomic sequences which incorporates descriptions of the basic transcriptional, translational and splicing signals, as well as length distributions and compositional features of ...
C. Burge, S. Karlin
semanticscholar   +1 more source

Gene Ontology: tool for the unification of biology

open access: yesNature Genetics, 2000
Michael Ashburner   +20 more
semanticscholar   +1 more source

The Molecular Signatures Database Hallmark Gene Set Collection

open access: yes, 2015
A. Liberzon   +5 more
semanticscholar   +1 more source

Differential gene and transcript expression analysis of RNA-seq experiments with TopHat and Cufflinks

open access: yesNature Protocols, 2012
C. Trapnell   +9 more
semanticscholar   +1 more source

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