Results 121 to 130 of about 11,841,902 (391)
FEBS Letters, EarlyView.Spinal muscular atrophy (SMA) is a genetic disease affecting motor neurons. Individuals with SMA experience mitochondrial dysfunction and oxidative stress. The aim of the study was to investigate the effect of an antioxidant and neuroprotective substance, ergothioneine (ERGO), on an SMNΔ7 mouse model of SMA.
Francesca Cadile +8 more
wiley +1 more source
Mitochondria as a Potential Antifungal Target for Isocyanide Compounds [PDF]
, 2020 The discovery of antibiotics and antifungals greatly impacted medicine and human health, allowing the effective treatment of infections that were previously deadly. However, due to routine and sometimes excessive usage of these compounds, the development
Berkowitz, David +5 more
core +1 more source
Coupling of adenovirus to transferrin-polylysine/DNA complexes greatly enhances receptor-mediated gene delivery and expression of transfected genes. [PDF]
, 1992 We are developing efficient methods for gene transfer into tissue culture cells. We have previously shown that coupling of a chimeric adenovirus with polylysine allowed the construction of an adenovirus-polylysine-reporter-gene complex that transferred ...
Birnstiel, Max L. +6 more
core +1 more source
Microbial exopolysaccharide production by polyextremophiles in the adaptation to multiple extremes
FEBS Letters, EarlyView.Polyextremophiles are microorganisms that endure multiple extreme conditions by various adaptation strategies that also include the production of exopolysaccharides (EPSs). This review provides an integrated perspective on EPS biosynthesis, function, and regulation in these organisms, emphasizing their critical role in survival and highlighting their ...
Tracey M Gloster, Ebru Toksoy Öner
wiley +1 more source
Combining ability and gene action studies for seed yield and its components in sesame (Sesamum indicum L.) [PDF]
Electronic Journal of Plant Breeding, 2014 A line x tester analysis using 12 lines and three testers was carried out to study the combining ability and gene action in sesame for seed yield and 14 quantitative traits.
Vavdiya, P. A., Dobariya, K. L. and Babariya, C. A.
doaj
The Plant Pathology Journal, 2016 Inheritance of resistance to Fusarium wilt (FW) disease caused by Fusarium udum was investigated in pigeonpea using four different long duration FW resistant genotypes viz., BDN-2004-1, BDN-2001-9, BWR-133 and IPA-234. Based on the F₂ segregation pattern,
Deepu Singh +6 more
doaj +1 more source
dCas9-based epigenome editing suggests acquisition of histone methylation is not sufficient for target gene repression. [PDF]
, 2017 Distinct epigenomic profiles of histone marks have been associated with gene expression, but questions regarding the causal relationship remain. Here we investigated the activity of a broad collection of genomically targeted epigenetic regulators that ...
Farnham, Peggy J +8 more
core +2 more sources
FEBS Letters, EarlyView.Nicotinamide (NIC) and nicotinic acid (NIA) are proposed as stress signaling compounds in plants. Oxidative stress may lead to single strand breaks (SSB) in DNA, which activate poly(ADP‐ribose) polymerase (PARP). NIC and NIA are then formed from NAD. NIC and NIA can promote epigenetic changes leading to the expression of defense genes specific for the ...
Torkel Berglund, Anna B. Ohlsson
wiley +1 more source
Scientia Agricola, 2005 The use of fungicides to control powdery mildew in sweet pepper has been ineffective and genetic resistance is the best alternative. Resistance sources identified in Capsicum annuum L. are rare and unsatisfactory.
Sally Ferreira Blat +3 more
doaj +1 more source
The parenting hub of the hypothalamus is a focus of imprinted gene action. [PDF]
PLoS Genet, 2023 Higgs MJ +5 more
europepmc +1 more source