Results 101 to 110 of about 7,371,567 (249)

FGFR2 gene amplification and clinicopathological features in gastric cancer

British Journal of Cancer, 2012
Background:Frequency of FGFR2 amplification, its clinicopathological features, and the results of high-throughput screening assays in a large cohort of gastric clinical samples remain largely unclear.Methods:Drug sensitivity to a fibroblast growth factor
Kazuko Matsumoto, T. Arao, T. Hamaguchi, Y. Shimada, K. Kato, I. Oda, H. Taniguchi, F. Koizumi, K. Yanagihara, Hiroki Sasaki, K. Nishio, Y. Yamada   +11 more
semanticscholar   +1 more source

Molecular Amplification and Cell Culturing Efficiency for Enteroviruses’ Detection in Cerebrospinal Fluids of Algerian Patients Suffering from Meningitis

Viruses
Enteroviruses (EVs) represent a major cause of viral meningitis, being responsible for nearly 1 billion infections each year worldwide. Several techniques were developed to obtain better diagnostic results of EV infections.
Abdelwahab Rai, Zohra Ammi, Dahbia Leila Anes-Boulahbal, Aymen Amin Assadi, Abdeltif Amrane, Oussama Baaloudj, Lotfi Mouni   +6 more
doaj   +1 more source

Study of C-MYC amplification and expression in Iranian gastric cancer samples using CISH and IHC methods

Advanced Biomedical Research, 2015
Background: Gastric cancer is the fourth most frequent malignancy and the second cause of cancer-related mortality worldwide. It has been suggested that in gastric carcinogenesis, the C-MYC gene has an important function.
Malihea Khaleghian, Issa Jahanzad, Abbas Shakoori, Farid Azmoudeh Ardalan, Cyrus Azimi   +4 more
doaj   +1 more source

High-Resolution Mapping of Genomic Imbalance and Identification of Gene Expression Profiles Associated with Differential Chemotherapy Response in Serous Epithelial Ovarian Cancer

Neoplasia: An International Journal for Oncology Research, 2005
Array comparative genomic hybridization (aCGH) and microarray expression profiling were used to subclassify DNA and RNA alterations associated with differential response to chemotherapy in ovarian cancer.
Marcus Bernardini, Chung-Hae Lee, Ben Beheshti, Mona Prasad, Monique Albert, Paula Marrano, Heather Begley, Patricia Shaw, Al Covens, Joan Murphy, Barry Rosen, Salomon Minkin, Jeremy A. Squire, Pascale F. Macgregor   +13 more
doaj   +1 more source

Exploring Life Detection on Mars: Understanding Challenges in DNA Amplification in Martian Regolith Analogue After Fe Ion Irradiation

Life
The search for life beyond Earth currently hinges on the detection of biosignatures that are indicative of current or past life, with terrestrial life being the sole known example.
Alessia Cassaro, Claudia Pacelli, Silvano Onofri   +2 more
doaj   +1 more source

HER2 and TOP2A in high-risk early breast cancer patients treated with adjuvant epirubicin-based dose-dense sequential chemotherapy

Journal of Translational Medicine, 2012
Background HER2 and TOP2A parameters (gene status, mRNA and protein expression) have individually been associated with the outcome of patients treated with anthracyclines.
Fountzilas George, Valavanis Christos, Kotoula Vassiliki, Eleftheraki Anastasia G, Kalogeras Konstantine T, Tzaida Olympia, Batistatou Anna, Kronenwett Ralf, Wirtz Ralph M, Bobos Mattheos, Timotheadou Eleni, Soupos Nikolaos, Pentheroudakis George, Gogas Helen, Vlachodimitropoulos Dimitrios, Polychronidou Genovefa, Aravantinos Gerasimos, Koutras Angelos, Christodoulou Christos, Pectasides Dimitrios, Arapantoni Petroula   +20 more
doaj   +1 more source

Amplified dihydrofolate reductase genes in unstably methotrexate-resistant cells are associated with double minute chromosomes. [PDF]

, 1979
Randal J. Kaufman, Peter C. Brown, Robert Schimke   +2 more
openalex   +1 more source

c-Myc-Induced Extrachromosomal Elements Carry Active Chromatin

Neoplasia: An International Journal for Oncology Research, 2003
Murine Pre-13 lymphocytes with experimentally activated MycER show both chromosomal and extrachromosomal gene amplification. In this report, we have elucidated the size, structure, functional components of c-Myc-induced extrachromosomal elements (EEs ...
Greg Smith, Cheryl Taylor-Kashton, Len Dushnicky, Stephen Symons, Jim Wright, Sabine Mai   +5 more
doaj   +1 more source

INDICATION OF GENE AMPLIFICATION IN RHYNCHOSCIARA BY RNA-DNA HYBRIDIZATION [PDF]

, 1971
R. Meneghini, Hugo A. Armelin, J. Bálsamo, Francisco J. Lara   +3 more
openalex   +1 more source

Flux variability scanning based on enforced objective flux for identifying gene amplification targets

BMC Systems Biology, 2012
BackgroundIn order to reduce time and efforts to develop microbial strains with better capability of producing desired bioproducts, genome-scale metabolic simulations have proven useful in identifying gene knockout and amplification targets.
J. Park, H. Park, W. Kim, H. Kim, T. Kim, S. Lee   +5 more
semanticscholar   +1 more source