Results 31 to 40 of about 3,599,711 (186)
Microvariation artifacts introduced by PCR and cloning of closely related 16S rRNA gene sequences [PDF]
, 2001 A defined template mixture of seven closely related 16S-rDNA clones was used in a PCR-cloning experiment to assess and track sources of artifactual sequence variation in 16S rDNA clone libraries. At least 14% of the recovered clones contained aberrations.
Speksnijder, Arjen +8 more
core +3 more sources
Induction of Gene Amplification Contribute to Sulfonamide Resistance in Proteus mirabilis [PDF]
مجلة التربية والعلم, 2007 Thirty Isolates of Proteus mirabilis from different clinical sources (Urine, Bum, Ear, and Wounds) were recovered. All isolates were subjected to the series of confirming tests to insure that these isolates are Proteus mirabilis, which identified ...
Zeerak Abdulrahman
doaj +1 more source
circRNA meets gene amplification [PDF]
Non-coding RNA Investigation, 2018 Lung cancer remains the most common cause of cancer related death among both males and females globally accounting for 1.69 million deaths in 2015 (1). Of the different types of lung cancer, lung adenocarcinoma (LAC) is the most common (2). Given the prevalence and lethality of lung cancer the need to elucidate the mechanisms of this disease and to ...
Nicholas, Manguso +2 more
openaire +2 more sources
Forensic Applications of Whole Genome Amplification [PDF]
, 2011 Whole genome amplification (WGA) has been touted as a possible technique to augment fragment analysis of STRs in amplifying low-levels of DNA recovered from crime scenes or items.
Williams, Graham
core +3 more sources
Frontiers in ImmunologyImmune-related cystitis is an uncommon immune-related adverse event (irAE) linked to immune checkpoint inhibitors (ICIs), and managing cases refractory to corticosteroids remains clinically challenging due to the lack of standardized treatment guidelines.
Lingping Kong +6 more
doaj +1 more source
Guidelines for DNA recombination and repair studies: Cellular assays of DNA repair pathways
Microbial Cell, 2019 Understanding the plasticity of genomes has been greatly aided by assays for recombination, repair and mutagenesis. These assays have been developed in microbial systems that provide the advantages of genetic and molecular reporters that can readily be ...
Hannah L. Klein +47 more
doaj +1 more source
Viral load could be an important determinant for fomites based transmission of viral infections
Journal of Family Medicine and Primary Care, 2021 Background and Objective: Fomites are common sources of transmission of certain infections. Infectious pathogens, such as viruses known to cause respiratory tract infections, are common examples of being transmitted by fomites.
Dhirendra P Singh +6 more
doaj +1 more source
Epigenetic regulation affects gene amplification in Drosophila development
Frontiers in Bioscience-Landmark, 2020 In Drosophila melanogaster, in response to developmental transcription factors, and by repeated initiation of DNA replication of four chorion genes, ovarian follicle cells, form an onion skin-type structure at the replication origins. The DNA replication
Hidetsugu Kohzaki +3 more
doaj +1 more source
Comparative Genomic Hybridization of Human Malignant Gliomas Reveals Multiple Amplification Sites and Nonrandom Chromosomal Gains and Losses [PDF]
, 1994 Nine human malignant gliomas (2 astrocytomas grade III and 7 glioblastomas) were analyzed using comparative genomic hybridization (CGH). In addition to the amplification of the EGFR gene at 7p12 in 4 of 9 cases, six new amplification sites were mapped to
Vogel, S. +13 more
core +1 more source
Microbiology Spectrum, 2022 Enhanced levels of resistance to antibiotics arising from amplification of an antibiotic resistance gene that impact therapeutic options are increasingly observed. Amplification can also disclose novel phenotypes leading to treatment failure.
Christopher J. Harmer +4 more
doaj +1 more source