Results 41 to 50 of about 3,599,711 (186)
BMC Cancer, 2018 Background Somatic amplifications of the LYL1 gene are relatively common occurrences in patients who develop uterine corpus endometrial carcinoma (UCEC) as opposed to other cancers.
Se Ik Kim +9 more
doaj +1 more source
Loop-mediated isothermal amplification (LAMP) method for rapid detection of Trypanosoma brucei rhodesiense [PDF]
, 2008 Loop-mediated isothermal amplification (LAMP) of DNA is a novel technique that rapidly amplifies target DNA under isothermal conditions. In the present study, a LAMP test was designed from the serum resistance-associated (SRA) gene of Trypanosoma brucei ...
Ndung'u, J.M. +5 more
core
Zhongliu Fangzhi Yanjiu, 2018 Objective To detect the amplification of HER2 gene by fluorescence in situ hybridization(FISH), and explore the correlation between HER2 gene amplification and clinicopathological characteristics. Methods We collected 325 cases of breast cancer with HER2(
ZHANG Mingshuai +5 more
doaj +1 more source
Gene amplification in Rhynchosciara (1955-1987)
Memorias do Instituto Oswaldo Cruz, 1987 A review is made of the evidence indicating the existence of gene amplification in Rhynchosciara, from the early cytological work to the more recent studies using cloned sequences from the DNA puffs.
Francisco J. S. Lara
doaj +1 more source
Cancer Biology & Medicine, 2021 Objective: Dysfunction in fibroblast growth factor receptor (FGFR) signaling has been reported in diverse cancer types, including non-small cell lung cancer (NSCLC).
Zhen Zhou +7 more
doaj +1 more source
MYCN gene amplification in rhabdomyosarcoma [PDF]
Cancer, 1994 Amplification of the MYCN oncogene, formerly known as N-myc, has been seen in several malignant tumors, particularly neuroblastoma, where its association with a poor clinical outcome is the clearest example of a clinically relevant oncogene mutation in any human cancer.The incidence and clinical significance of MYCN amplification in rhabdomyosarcoma ...
D, Driman +4 more
openaire +2 more sources
A rare epidermal growth factor receptor (EGFR) gene mutation in small cell lung carcinoma patients
Biomedical Papers, 2022 Aim. Activating mutations in the epidermal growth factor receptor (EGFR) are predominantly detected in pulmonary adenocarcinoma and have been reported in small cell lung cancer (SCLC) for decades. This retrospective single-center study aimed to determine
Cheng-Cheng Hwang +6 more
doaj +1 more source
The MDM2 gene amplification database [PDF]
Nucleic Acids Research, 1998 The p53 tumor suppressor gene is inactivated in human tumors by several distinct mechanisms. The best characterized inactivation mechanisms are: (i) gene mutation; (ii) p53 protein association with viral proteins; (iii) p53 protein association with the MDM2 cellular oncoprotein. The MDM2 gene has been shown to be abnormally up-regulated in human tumors
J, Momand +3 more
openaire +2 more sources
Cells, 2022 Gene amplifications in amphibians and flies are known to occur during development and have been well characterized, unlike in mammalian cells, where they are predominantly investigated as an attribute of tumors.
Marie Minet +8 more
doaj +1 more source
Polymerase-endonuclease amplification reaction for large-scale enzymatic production of antisense oligonucleotide [PDF]
, 2009 Synthetic oligonucleotides are contaminated with highly homologous failure sequences. Oligonucleotide synthesis is difficult to scale up because it requires expensive equipments, hazardous chemicals, and tedious purification process.
Deming Gou, Xiaolong Wang
core