Results 161 to 170 of about 3,964,704 (304)

Un método de transformación genética de maíz para conferirle resistencia ulterior a enfermedades virales

open access: yesRevista de Biología Tropical, 2004
Se desarrolló un sistema de transformación genética para dos variedades costarricenses de maíz: CR-7 y Diamantes 8843, que permita la transferencia ulterior de genes de origen viral a su genoma, y conferirles resistencia a la enfermedad ocasionada por el
Marta Valdez   +2 more
doaj  

Registration Brochure: State Bar of Texas Annual Meeting, 2014

open access: yes, 2014
Pamphlet for the State Bar of Texas's Annual Meeting held June 26-27, 2014.
State Bar of Texas
core  

Translating whole‐genome doubling into precision medicine in cancer

open access: yesMolecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

open access: yesMolecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Creation of the expressing constructions with bar gene for plant transformation [PDF]

open access: yesBiopolymers and Cell, 1994
A. I. Zayas   +3 more
openaire   +1 more source

Proceedings of the Montana Bar Association.

open access: yes, 1902
Vols. for 1925-1928 called also 39th-42nd annual meeting.Publication suspended 1915-1920.Mode of access: Internet.Continued 1949-61 in Montana law review; 1963- in Montana Bar Association ...
Montana Bar Association.
core  

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

open access: yesMolecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu   +3 more
wiley   +1 more source

Les Ducs de Bar ou seigneurs et dames de Cassel de la maison ducale de Bar /

open access: yes, 1884
Overdruk uit : Mémoires de la société des Lettres, Sciences et Arts de Bar-le-Duc.
de Smyttère, Philippe-Joseph-Emmanuel,1800-1886(viaf)79064893
core  

CEACAM1 participation in breast cancer progression

open access: yesMolecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin   +3 more
wiley   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

open access: yesMolecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas   +16 more
wiley   +1 more source

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