Evaluating the effect of γ‐oryzanol on MASLD pathology using a medaka fish model
This study explores a liver disease called MASLD, which is increasing worldwide and can lead to serious damage. Researchers used medaka fish instead of rodents to test a food compound, γ‐oryzanol. Fish fed this compound had less liver fat and healthier gut bacteria.
Yukako Ito +7 more
wiley +1 more source
Establishment of an efficient <i>Agrobacterium</i>-mediated genetic transformation protocol for <i>Saccharum officinarum</i> using Black Cheribon as a model genotype. [PDF]
Li C +8 more
europepmc +1 more source
Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA
Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley +1 more source
Sunitinib induces macrophage dysfunction and impaired tissue regeneration through suppression of PPARγ. [PDF]
Zhang Z +9 more
europepmc +1 more source
Identification of (20R)‐protopanaxadiol from Panax ginseng as a novel anti‐SARS‐CoV‐2 compound
We established a noninfectious BAC‐based SARS‐CoV‐2 replicon that enables antiviral screening under BSL‐2 conditions. Using this platform, we screened 373 food‐derived compounds and identified (20R)‐protopanaxadiol from Panax ginseng as a novel inhibitor of SARS‐CoV‐2 RNA replication, highlighting the value of safe replicon systems for antiviral ...
Midori Takeda +4 more
wiley +1 more source
Machine learning-based identification of hub genes and prognostic biomarkers in prostate cancer. [PDF]
Chen G, Zhang J, Zhao L, Zhu J.
europepmc +1 more source
<i>In vivo</i> porcine multi-omics integration identifies microbiome-driven histamine elevation and lasting gut perturbations following <i>Ascaris suum</i> infection and fenbendazole treatment. [PDF]
Liu F +6 more
europepmc +1 more source
Involvement of ascorbate oxidase in the regulation of the leaf development mediated by mepiquat chloride in cotton seedlings. [PDF]
Tian Y +6 more
europepmc +1 more source

