Results 81 to 90 of about 3,964,704 (304)
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Cross-Platform Analysis with Binarized Gene Expression Data
, 2009 With widespread use of microarray technology as a potential diagnostics tool, the comparison of results obtained from the use of different platforms is of interest.
Tuna, Salih +3 more
core +2 more sources
A Macrohistone Variant Links Dynamic Chromatin Compaction to BRCA1-Dependent Genome Maintenance
Cell Reports, 2014 Appropriate DNA double-strand break (DSB) repair factor choice is essential for ensuring accurate repair outcome and genomic integrity. The factors that regulate this process remain poorly understood. Here, we identify two repressive chromatin components,
Simran Khurana +10 more
doaj +1 more source
Lockwood Letter. (Toledo, Ohio), April 1986
, 2019 The Lockwood Letter is a newspaper published by the Toledo Women's Bar Association published in part to "promote and advance the position of and opportunities available to women attorneys" in the Toledo ...
Toledo Women's Bar Association
core
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Revista Colombiana de Biotecnología, 2010 Título en inglés: New method for rapid selection of banana (Musa spp. AAA cv. Grande naine) plants with bar gene in the field using ammonium gluphosinate Resumen Los genes marcadores de la selección son ampliamente utilizados para la ...
Rafael Gómez-Kosky +4 more
doaj +2 more sources
Colorectal cancer biofilm composition reveals distinct bacterial species signature
Applied Microbiology and BiotechnologyHuman colon hosts a highly organized protective microbial ecosystem in the form of biofilms, increasingly recognized as key contributors to colorectal cancer (CRC) progression through microbial dysbiosis and complex host-microbiota interactions. In India,
Manish Kushwaha +6 more
doaj +1 more source
Lockwood Letter. (Toledo, Ohio), July 1991
, 2019 The Lockwood Letter is a newspaper published by the Toledo Women's Bar Association published in part to "promote and advance the position of and opportunities available to women attorneys" in the Toledo ...
Toledo Women's Bar Association
core
Association of the AFF3 gene and IL2/IL21 gene region with juvenile idiopathic arthritis [PDF]
, 2010 Recent genetic studies have led to identification of numerous loci that are associated with susceptibility to autoimmune diseases. The strategy of using information from these studies has facilitated the identification of novel juvenile idiopathic ...
S Eyre +21 more
core +1 more source
Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source