Results 261 to 270 of about 497,526 (307)
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Biochemical Genetics, 1994
We report the isolation of nine rat cognates of mouse homeoboxes within the four Hox gene clusters and a rat homologue of mouse IPF1 homeobox, RHbox#13A. The sequences of nine cloned homeoboxes are highly similar to those of the mouse and human homeoboxes in the Hox clusters. The restriction enzyme sites and map distances between each of the homeoboxes
Y, Sakoyama +3 more
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We report the isolation of nine rat cognates of mouse homeoboxes within the four Hox gene clusters and a rat homologue of mouse IPF1 homeobox, RHbox#13A. The sequences of nine cloned homeoboxes are highly similar to those of the mouse and human homeoboxes in the Hox clusters. The restriction enzyme sites and map distances between each of the homeoboxes
Y, Sakoyama +3 more
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Cloning the chicken leptin gene
Gene, 1998Chicken is characterized by a relative insulin resistance and a physiological hyperglycemia (2g/L) and is also subjected to fattening. Fat deposits in chicken, as in mammals, are regulated by environmental and genetic factors. In mammals, leptin, an adipose cell-specific secreted protein has been characterized that is encoded by ob gene.
Taouis, Mohammed +5 more
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Positional cloning of the APECED gene
Nature Genetics, 1997Autoimmune polyglandular syndrome type I (APS 1, also called APECED) is an autosomal-recessive disorder that maps to human chromosome 21q22.3 between markers D21S49 and D21S171 by linkage studies. We have isolated a novel gene from this region, AIRE (autoimmune regulator), which encodes a protein containing motifs suggestive of a transcription factor ...
Nagamine, K. +13 more
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From Clones of Cells to Cloned Genes and the Proteinpaedia
Scandinavian Journal of Immunology, 2005AbstractThis brief description follows the association of the author with Ivan Lefkovits from 1971 until this volume. Sketches of our mutual interests are included. Time periods in California, Basel and Texas are described. Decisions about preparing new tools for clonal analysis are elucidated, and experimental approaches leading to the x‐omic ...
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Cloning of the human myoglobin gene
Gene, 1985Genomic clones that contain the human myoglobin gene were isolated by cross-hybridization to the porcine myoglobin cDNA from human genomic libraries. The myoglobin gene is about 10.5 kb long and contains two introns as in the case with hemoglobin genes.
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CLONING OF FIBRINOGEN GENES AND THEIR cDNA*
Annals of the New York Academy of Sciences, 1983Cross-species hybridizations have enabled us to isolate and clone the gene for the beta chain of human fibrinogen. Highlights of the gene for the beta chain revealed by nucleotide sequence analyses, particularly in areas that have a direct bearing on defining the overall organization of the gene, have been presented.
D W, Chung +3 more
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Cloning of a eukaryotic regulatory gene
Molecular and General Genetics MGG, 1981From a pool of hybrid plasmids carrying Sau3A fragments representing the entire yeast (S. cerevisiae) genome, a DNA fragment containing the regulatory gene PPRI was cloned by complementation of a non-inducible ppr1 mutation which confers to the cells an increased sensitivity to 6-azauracil. Cells containing the cloned DNA regained the ability to induce
R, Losson, F, Lacroute
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1985
Little is known about the molecular basis for differential gene expression during muscle development, the assembly of contractile proteins into filament lattices, or the functions of contractile protein isoforms in different muscle tissues. The small soil nematode Caenorhabditis elegans is an attractive organism in which to apply biochemical and ...
J, Karn, N J, Dibb, D M, Miller
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Little is known about the molecular basis for differential gene expression during muscle development, the assembly of contractile proteins into filament lattices, or the functions of contractile protein isoforms in different muscle tissues. The small soil nematode Caenorhabditis elegans is an attractive organism in which to apply biochemical and ...
J, Karn, N J, Dibb, D M, Miller
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Cell Biology International Reports, 1978
Abstract The major problem in studying gene expression in eukaryotic organisms is the complexity of the eukaryotic genome. We would like to have the same detailed understanding of the genetics of eukaryotes as has been obtained for λ bacteriophage but are faced with the daunting statistic that the human genome could accommodate nearly 100,000 times ...
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Abstract The major problem in studying gene expression in eukaryotic organisms is the complexity of the eukaryotic genome. We would like to have the same detailed understanding of the genetics of eukaryotes as has been obtained for λ bacteriophage but are faced with the daunting statistic that the human genome could accommodate nearly 100,000 times ...
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Gene Cloning with Small Plasmids
1977The following account of the use of plasmids in gene cloning is an attempt to present this technique against a background of its subsidiary techniques—plasmid genetics, DNA biochemistry, bacterial transformation etc. —while at the same time considering the ways in which the field is likely to develop in view of the particular aims of different ...
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