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Dendrimers in gene delivery [PDF]
Advanced Drug Delivery Reviews, 2005 Dendrimers have unique molecular architectures and properties that make them attractive materials for the development of nanomedicines. Key properties such as defined architecture and a high ratio of multivalent surface moieties to molecular volume also ...
Dufès, Christine +2 more
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Recent advances in the development of gene delivery systems
Biomaterials Research, 2019 Background Gene delivery systems are essentially necessary for the gene therapy of human genetic diseases. Gene therapy is the unique way that is able to use the adjustable gene to cure any disease.
YK Sung, SW Kim
doaj +2 more sources
Receptor-Mediated Gene Delivery [PDF]
The Scientific World Journal, 2002 Receptor-mediated gene delivery capitalises on the presence of specific cell surface molecules for DNA uptake into cells and represents a particularly appealing approach for targeting vector DNA to specific cell types in vivo and in vitro. Various ligand/
Tatjana C. Gust, Martin Zenke
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Emerging non-viral vectors for gene delivery
Journal of Nanobiotechnology, 2023 Gene therapy holds great promise for treating a multitude of inherited and acquired diseases by delivering functional genes, comprising DNA or RNA, into targeted cells or tissues to elicit manipulation of gene expression.
Chenfei Wang +8 more
semanticscholar +1 more source
Stimuli-Responsive Gene Delivery Nanocarriers for Cancer Therapy
Nano-Micro Letters, 2023 Gene therapy provides a promising approach in treating cancers with high efficacy and selectivity and few adverse effects. Currently, the development of functional vectors with safety and effectiveness is the intense focus for improving the delivery of ...
Qingfei Zhang +5 more
semanticscholar +1 more source
Emerging Roles of Green-Synthesized Chalcogen and Chalcogenide Nanoparticles in Cancer Theranostics
Journal of Nanotechnology, 2022 The last few decades have seen an overwhelming increase in the amount of research carried out on the use of inorganic nanoparticles. More fascinating is the tremendous progress made in the use of chalcogen and chalcogenide nanoparticles in cancer ...
Femi Olawale +3 more
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Nature Immunology, 2022 The ability of immune-modulating biologics to prevent and reverse pathology has transformed recent clinical practice. Full utility in the neuroinflammation space, however, requires identification of both effective targets for local immune modulation and ...
L. Yshii +41 more
semanticscholar +1 more source
Hybrid Membrane-Derived Nanoparticles for Isoliquiritin Enhanced Glioma Therapy
Pharmaceuticals, 2022 Due to the obstruction and heterogeneity of the blood-brain barrier, the clinical treatment of glioma has been extremely difficult. Isoliquiritigenin (ISL) exhibits antitumor effects, but its low solubility and bioavailability limit its application ...
Wenwan Shi +10 more
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Journal of Nanobiotechnology, 2022 Nanoparticles have been widely applied as gene carrier for improving RNA interference (RNAi) efficiency in medical and agricultural fields. However, the mechanism and delivery process of nanoparticle-mediated RNAi is not directly visualized and ...
Zhongzheng Ma +7 more
semanticscholar +1 more source
Carbon Nanotubes: Smart Drug/Gene Delivery Carriers
International Journal of Nanomedicine, 2021 The unique properties of carbon nanotubes (CNTs) (such as their high surface to volume ratios, enhanced conductivity and strength, biocompatibility, ease of functionalization, optical properties, etc.) have led to their consideration to serve as novel ...
Hossein Zare +9 more
semanticscholar +1 more source