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Gene delivery to the epidermis [PDF]
Human Molecular Genetics, 1997 Epidermal gene delivery techniques are being developed as an experimental approach to understanding the pathogenesis of skin disorders and for developing therapeutic strategies for the treatment of disease. This technology is being evaluated in many clinical trials in the treatment of disorders such as cutaneous melanoma and skin wounding, with 20% of ...
Alison Trainer
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Biodegradable Polymers for Gene Delivery [PDF]
Molecules, 2019 The cellular transport process of DNA is hampered by cell membrane barriers, and hence, a delivery vehicle is essential for realizing the potential benefits of gene therapy to combat a variety of genetic diseases.
T. Thomas, H. Tajmir-Riahi, C. Pillai
semanticscholar +4 more sources
Recent advances in the development of gene delivery systems
Biomaterials Research, 2019 Background Gene delivery systems are essentially necessary for the gene therapy of human genetic diseases. Gene therapy is the unique way that is able to use the adjustable gene to cure any disease.
YK Sung, SW Kim
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Receptor-Mediated Gene Delivery [PDF]
The Scientific World Journal, 2002 Receptor-mediated gene delivery capitalises on the presence of specific cell surface molecules for DNA uptake into cells and represents a particularly appealing approach for targeting vector DNA to specific cell types in vivo and in vitro. Various ligand/
Tatjana C. Gust, Martin Zenke
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Viral and nonviral delivery systems for gene delivery
Advanced Biomedical Research, 2012 Gene therapy is the process of introducing foreign genomic materials into host cells to elicit a therapeutic benefit. Although initially the main focus of gene therapy was on special genetic disorders, now diverse diseases with different patterns of ...
Nouri Nayerossadat +2 more
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Emerging non-viral vectors for gene delivery
Journal of Nanobiotechnology, 2023 Gene therapy holds great promise for treating a multitude of inherited and acquired diseases by delivering functional genes, comprising DNA or RNA, into targeted cells or tissues to elicit manipulation of gene expression.
Chenfei Wang +8 more
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Stimuli-Responsive Gene Delivery Nanocarriers for Cancer Therapy
Nano-Micro Letters, 2023 Gene therapy provides a promising approach in treating cancers with high efficacy and selectivity and few adverse effects. Currently, the development of functional vectors with safety and effectiveness is the intense focus for improving the delivery of ...
Qingfei Zhang +5 more
semanticscholar +1 more source
Nature Immunology, 2022 The ability of immune-modulating biologics to prevent and reverse pathology has transformed recent clinical practice. Full utility in the neuroinflammation space, however, requires identification of both effective targets for local immune modulation and ...
L. Yshii +41 more
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Carbon Nanotubes: Smart Drug/Gene Delivery Carriers
International Journal of Nanomedicine, 2021 The unique properties of carbon nanotubes (CNTs) (such as their high surface to volume ratios, enhanced conductivity and strength, biocompatibility, ease of functionalization, optical properties, etc.) have led to their consideration to serve as novel ...
Hossein Zare +9 more
semanticscholar +1 more source
Emerging Roles of Green-Synthesized Chalcogen and Chalcogenide Nanoparticles in Cancer Theranostics
Journal of Nanotechnology, 2022 The last few decades have seen an overwhelming increase in the amount of research carried out on the use of inorganic nanoparticles. More fascinating is the tremendous progress made in the use of chalcogen and chalcogenide nanoparticles in cancer ...
Femi Olawale +3 more
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