Results 241 to 250 of about 9,198,934 (404)

Gene delivery of albumin binding peptide-interferon-gamma fusion protein with improved pharmacokinetic properties and sustained biological activity [PDF]

, 2013
N Miyakawa, Makiya Nishikawa, Yuki Takahashi, Mitsuru Ando, Masayuki Misaka, Yoshihiko Watanabe, Yoshinobu Takakura   +6 more
openalex   +1 more source

Adenovirus-mediated gene delivery: Potential applications for gene and cell-based therapies in the new era of personalized medicine

Genes and Diseases, 2017
Cody S. Lee, Elliot S. Bishop, Ruyi Zhang, Xinyi Yu, Evan M. Farina, Shujuan Yan, Chen Zhao, Z. Zeng, Y. Shu, Xing-ye Wu, J. Lei, Yasha Li, Wenwen Zhang, Chao Yang, Kevin J. Wu, Ying Wu, Sherwin S. Ho, A. Athiviraham, Michael J. Lee, J. Wolf, R. Reid, T. He   +21 more
semanticscholar   +1 more source

Peptide Sequencing With Single Acid Resolution Using a Sub‐Nanometer Diameter Pore

Advanced Functional Materials, EarlyView.
To sequence a single molecule of Aβ1−42–sodium dodecyl sulfate (SDS), the aggregate is forced through a sub‐nanopore 0.4 nm in diameter spanning a 4.0 nm thick membrane. The figure is a visual molecular dynamics (VMD) snapshot depicting the translocation of Aβ1−42–SDS through the pore; only the peptide, the SDS, the Na+ (yellow/green) and Cl− (cyan ...
Apurba Paul, Archith Rayabharam, Lisa Almonte, Eveline Rigo, Joshy Joseph, Ashutosh Kumar, Zhuxin Dong, Narayana Aluru, Gregory Timp   +8 more
wiley   +1 more source

Engineering filamentous potato virus X as a platform nanotechnology for nucleic acid gene delivery. [PDF]

Sci Rep
Duoto B, Tong M, Barkovich KJ, Schuphan J, Mali P, Steinmetz NF.   +5 more
europepmc   +1 more source

A Smart Bio‐Battery Facilitates Diabetic Bone Defect Repair Via Inducing Macrophage Reprogramming and Synergistically Modulating Bone Remodeling Coupling

Advanced Functional Materials, EarlyView.
This research presents a novel implantable bio‐battery, GF‐OsG, tailored for diabetic bone repair. GF‐OsG generates microcurrents in high‐glucose conditions to enhance vascularization, shift macrophages to the M2 phenotype, and regulate immune responses.
Nanning Lv, Haifu Sun, Wenxiang Tang, Yonggang Li, Zhonglai Qian, Lihui Hong, Chong Chen, Hongye Li, Jiaxiang Bai, Yusen Qiao, Mingming Liu   +10 more
wiley   +1 more source

Engineering, delivery, and biological validation of artificial microRNA clusters for gene therapy applications

, 2019
Vivek Bhaskaran, Yizheng Yao, Fengfeng Bei, Pierpaolo Peruzzi   +3 more
openalex   +1 more source

Region‐to‐Region Unidirectional Connection In Vitro Brain Model for Studying Directional Propagation of Neuropathologies

Advanced Functional Materials, EarlyView.
A unidirectional cerebral organoid–organoid neural circuit is established using a microfluidic platform, enabling controlled directional propagation of electrical signals, neuroinflammatory cues, and neurodegenerative disease–related proteins between spatially separated organoids.
Kyeong Seob Hwang, Hui‐Wen Liu, Hyogeun Shin, Hyun Wook Kang, Minjin Kang, Jongbaeg Kim, Il‐Joo Cho, Nakwon Choi, Seok Chung, Hong Nam Kim   +9 more
wiley   +1 more source

Emerging Research on Gene Delivery to the Nucleus via DNA Origami. [PDF]

JACS Au
Sterling S, Wei Y, Arya G, Castro C, Ke Y.   +4 more
europepmc   +1 more source

High‐Spatiotemporal‐Resolution Transparent Thermoelectric Temperature Sensor Arrays Reveal Temperature‐Dependent Windows for Reversible Photothermal Neuromodulation

Advanced Functional Materials, EarlyView.
Thermoelectric temperature sensors are developed that directly measure heat changes during optical‐based neural stimulation with millisecond precision. The sensors reveal the temperature windows for safe reversible neural modulation: 1.4–4.5 °C enables reversible neural inhibition, while temperatures above 6.1 °C cause permanent thermal damage.
Junhee Lee, Dongjo Yoon, Jungha Lee, Duhee Kim, Eunui Kim, Jong‐Hyeok Yoon, Hyuk‐Jun Kwon, Seungjun Chung, Yoonkey Nam, Hongki Kang   +9 more
wiley   +1 more source

Multiscale red blood cell hitchhiking for targeted deep tissue gene delivery in lungs. [PDF]

Nat Commun
Park KS, Chandran Suja V, Kim J, Rodrigues D, Mukherji M, Joshi M, Gao Y, Bibbey MG, Choi JW, Liao R, Janes ME, Erdi M, Da Silva Candal A, Cameron DL, Halmai JANM, Fink KD, Mitragotri S, Singh B.   +17 more
europepmc   +1 more source