Results 61 to 70 of about 20,871,284 (295)
A Bibliometric Analysis of the Gene Delivery Systems for Lung Cancer from 2010 to 2022
Pharmaceutical FrontsThe gene delivery systems (GDS) for lung cancer (LC) has made significant progress over the past 12 years, yet, there is a great challenge in its clinical application due to low delivery efficiency.
Kexin Wu +5 more
doaj +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Efficient gene delivery system mediated by cis-aconitate-modified chitosan-g-stearic acid micelles
International Journal of Nanomedicine, 2014 Jing-Jing Yao, Yong-Zhong Du, Hong Yuan, Jian You, Fu-Qiang HuCollege of Pharmaceutical Sciences, Zhejiang University, Hangzhou, People’s Republic of ChinaAbstract: Cis-aconitate-modified chitosan-g-stearic acid (CA-CSO-SA) micelles were ...
Yao JJ, Du YZ, Yuan H, You J, Hu FQ
doaj
Recent advances in polymeric drug delivery systems
Biomaterials Research, 2020 Background Polymeric drug delivery systems have been achieved great development in the last two decades. Polymeric drug delivery has defined as a formulation or a device that enables the introduction of a therapeutic substance into the body ...
Yong Kiel Sung, Sung Wan Kim
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Intelligent nanotherapeutic strategies for the delivery of CRISPR system
Acta Pharmaceutica Sinica B, 2023 CRISPR, as an emerging gene editing technology, has been widely used in multiple fields due to its convenient operation, less cost, high efficiency and precision.
Chao Chen +8 more
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Decationized polyplexes for gene delivery [PDF]
, 2014 Gene therapy has received much attention in the field of drug delivery. Synthetic, nonviral gene delivery systems have gained increasing attention as vectors for gene therapy mainly due to a favorable immunogenicity profile and ease of manufacturing as ...
Pharmaceutics +13 more
core +2 more sources
The human gut microbiome across the life course
FEBS Letters, EarlyView.Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero +4 more
wiley +1 more source
FEBS Letters, EarlyView.This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley +1 more source
NanomaterialsDrug delivery vehicles composed of lipids and gemini surfactants (GS) are promising in gene therapy. Tuning the composition and properties of the delivery vehicle is important for the efficient load and delivery of DNA fragments (genes).
Robert D. E. Henderson +5 more
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Targeted Gene Delivery through the Respiratory System: Rationale for Intratracheal Gene Transfer
Journal of Cardiovascular Development and Disease, 2019 Advances in DNA- and RNA-based technologies have made gene therapy suitable for many lung diseases, especially those that are hereditary. The main objective of gene therapy is to deliver an adequate amount of gene construct to the intended target cell ...
Michael G. Katz +7 more
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