Results 241 to 250 of about 7,614,096 (384)

Tracking Motor Progression and Device‐Aided Therapy Eligibility in Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To characterise the progression of motor symptoms and identify eligibility for device‐aided therapies in Parkinson's disease, using both the 5‐2‐1 criteria and a refined clinical definition, while examining differences across genetic subgroups.
David Ledingham, Sahana Sathyanarayana, Charlotte B. Stewart, Robyn Iredale, Victoria Foster, Debra Galley, Mark Baker, Nicola Pavese   +7 more
wiley   +1 more source

Visual Recovery Reflects Cortical MeCP2 Sensitivity in Rett Syndrome

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Rett syndrome (RTT) is a devastating neurodevelopmental disorder with developmental regression affecting motor, sensory, and cognitive functions. Sensory disruptions contribute to the complex behavioral and cognitive difficulties and represent an important target for therapeutic interventions.
Alex Joseph Simon, Nathalie Picard, Valeria d'Andrea, Enchi Chang, Joseph Leffler, Eleonora Centofante, Matthew Taylor, Francesca Bardi, Francesca Cavicchiolo, Takao K. Hensch, Stefano Panzeri, Chinfei Chen, Michela Fagiolini   +12 more
wiley   +1 more source

Reduced Gene Dosage of the Psychiatric Risk Gene <i>Cacna1c</i> Is Associated with Impairments in Hypothalamic-Pituitary-Adrenal Axis Activity in Rats. [PDF]

Int J Mol Sci
Moon AL, Mawson ER, Gasalla P, Wilkinson LS, Dwyer DM, Hall J, Thomas KL.   +6 more
europepmc   +1 more source

Age, brain region, and gene dosage-differential transcriptomic changes in Shank3-mutant mice. [PDF]

Front Mol Neurosci, 2022
Yoo T, Yoo YE, Kang H, Kim E.
europepmc   +1 more source

The role of histone modifications and transposable elements in the epigenetic regulation of gene dosage after gene duplication [PDF]

Thomas Wolfe, Frédéric J. J. Chain
openalex   +1 more source

Gene dosage of <i>PDR16</i> modulates azole susceptibility in <i>Candida auris</i>. [PDF]

Microbiol Spectr
Phan-Canh T, Bitencourt T, Kuchler K.
europepmc   +1 more source

Gene dosage changes in KCTD13 result in penile and testicular anomalies via diminished androgen receptor function. [PDF]

FASEB J, 2022
Seth A, Rivera A, Chahdi A, Choi IS, Medina-Martinez O, Lewis S, O'Neill M, Ridgeway A, Moore J, Jorgez C, Lamb DJ.   +10 more
europepmc   +1 more source

Relapsing–Remitting Multiple Sclerosis Is Associated With a Dysbiotic Oral Microbiome

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Multiple sclerosis (MS) is a chronic autoimmune disorder characterized by inflammation, demyelination, and neurological impairment. While the gut microbiota's role in MS is extensively studied, the association between the oral microbiota and MS remains underexplored, particularly in North American cohorts.
Sukirth M. Ganesan, Meeta Yadav, Sudeep Ghimire, Peter C. Lehman, Apurva J. Patel, Sydney Woods, Heena Olalde, Jemmie Hoang, Mishelle Paullus, Catherine Cherwin, Christine Gill, Tracey Cho, Ashutosh K. Mangalam   +12 more
wiley   +1 more source

Increased gene dosage and mRNA expression from chromosomal duplications in Caenorhabditis elegans. [PDF]

G3 (Bethesda), 2022
Ragipani B, Albritton SE, Morao AK, Mesquita D, Kramer M, Ercan S.   +5 more
europepmc   +1 more source

The non-dosage compensated Lsp1α gene of Drosophila melanogaster escapes acetylation by MOF in larval fat body nuclei, but is flanked by two dosage compensated genes [PDF]

, 2007
Vikki M. Weake, Maxwell J. Scott
openalex   +1 more source