Results 61 to 70 of about 408,305 (347)

Complex Evolutionary History of the Y Chromosome in Flies of the Drosophila obscura Species Group. [PDF]

, 2020
The Drosophila obscura species group shows dramatic variation in karyotype, including transitions among sex chromosomes. Members of the affinis and pseudoobscura subgroups contain a neo-X chromosome (a fusion of the X with an autosome), and ancestral Y ...
Bachtrog, Doris, Bracewell, Ryan
core  

Characterization and Comparison of 2 Distinct Epidemic Community-Associated Methicillin-Resistant Staphylococcus aureus Clones of ST59 Lineage. [PDF]

, 2013
Sequence type (ST) 59 is an epidemic lineage of community-associated (CA) methicillin-resistant Staphylococcus aureus (MRSA) isolates. Taiwanese CA-MRSA isolates belong to ST59 and can be grouped into 2 distinct clones, a virulent Taiwan clone and a ...
A Bera, A Holmes, AE Fossum, AM Milstone, B Loffler, BA Diep, BE Gonzalez, BE Gonzalez, C Goerke, C Weidenmaier, Chih-Jung Chen, CJ Chen, CJ Chen, CJ Chen, CJ Chen, CJC de Haas, Clemens Unger, CP Montgomery, dS Aires, FC Tenover, FJ Chen, Friedrich Götz, GM Pupo, GW Coombs, J Bubeck Wardenburg, J Bubeck Wardenburg, J Kaneko, JM Voyich, Jodi A. Lindsay, K Georgiades, KB Kiser, LY Hsu, M Labandeira-Rey, M Otto, MR Mulvey, MZ David, N Zetola, Paul J. Planet, PE Fournier, PL Ho, R Wang, S Herbert, SHM Rooijakkers, SL Kaplan, T Jin, T Jin, V Merhej, WJ Wannet, WJB van Wamel, Wolfgang Hoffmann, Y Gillet, YC Huang, YC Huang, YC Huang, YC Huang, Yhu-Chering Huang   +55 more
core   +3 more sources

The Fate (Outcome) of Clinically Apparent Single Lesion and Oligofocal Nephroblastomatosis Treated According to SIOP/GPOH Protocols for Wilms Tumor

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background The management of clinically apparent single lesions or oligofocal nephroblastomatosis, a facultative precursor of nephroblastoma, remains debated. Methods We retrospectively analyzed 37 patients with clinically apparent single or oligofocal nephroblastomatosis (two to three lesions per kidney) among 2347 patients registered between
Nils Welter, Jens‐Peter Schenk, Jenny Wegert, Manfred Gessler, Leo Kager, Stefan Wagenpfeil, Marina Müller, Jean‐Michel Wolff, Joerg Fuchs, Steven W. Warmann, Clemens‐Magnus Meier, Jochen Hubertus, Christian Rübe, Christian Vokuhl, Patrick Melchior, Lena Tschirner, Norbert Graf, Rhoikos Furtwängler   +17 more
wiley   +1 more source

Stochastic model of transcription factor-regulated gene expression [PDF]

, 2006
We consider a stochastic model of transcription factor (TF)-regulated gene expression. The model describes two genes: Gene A and Gene B which synthesize the TFs and the target gene proteins respectively.
Alberts B, Bose I, Ferrer J, Fodde R, Ghosh B, Hume D A, Indrani Bose, Karmakar R, Kepler T B, Rajesh Karmakar, Santarosa M, Scott M   +11 more
core   +2 more sources

Efficacy and Safety Analysis of Roxarestat in Regulating Renal Anemia in Patients on Maintenance Hemodialysis

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Objective To compare the efficacy and safety of roxarestat versus recombinant human erythropoietin (rhEPO) in the management of renal anemia in patients undergoing maintenance hemodialysis. Methods This was a prospective, open‐label, randomized controlled trial.
Lingling Chen, Junjie Zhu, Qiaonan Ge
wiley   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Compensation of Dosage-Sensitive Genes on the Chicken Z Chromosome. [PDF]

, 2016
In many diploid species, sex determination is linked to a pair of sex chromosomes that evolved from a pair of autosomes. In these organisms, the degeneration of the sex-limited Y or W chromosome causes a reduction in gene dose in the heterogametic sex ...
Dessimoz, C., Harrison, P.W., Mank, J.E., Zimmer, F.   +3 more
core   +2 more sources

Genome-wide gene/genome dosage imbalance regulates gene expressions in synthetic Brassica napus and derivatives (AC, AAC, CCA, CCAA)

Frontiers in Plant Science, 2016
Gene/genome dosage balance is an essential evolutionary mechanism for organisms to ensure a normal function, but the underlying causes of dosage-imbalance regulation remain poorly understood.
Chen Tan, Qi Pan, Cheng Cui, Yi Xiang, Xianhong Ge, Zaiyun Li   +5 more
doaj   +1 more source

Genetic polymorphism of cytochrome p450 (2C19) enzyme in Iranian Turkman ethnic group [PDF]

, 2013
Objective: Different findings indicate that CYP2C plays a clinical role in determining interindividual and interethnic differences in drug effectiveness. The ethnic differences in the frequency of CYP2C19 mutant alleles continue to be a significant study
Ataby, O.A., Mansourian, A.R., Marjani, A., Samai, N.M., Tabari, R.G.   +4 more
core   +2 more sources

Inversely proportional myelin growth due to altered Pmp22 gene dosage identifies PI3K/Akt/mTOR signaling as a novel therapeutic target in HNPP [PDF]

, 2021
Doris Krauter, David Ewers, Timon J Hartmann, Stefan Volkmann, Theresa Kungl, Robert Fledrich, Sandra Goebbels, Klaus‐Armin Nave, Michael W. Sereda   +8 more
openalex   +1 more source