Results 111 to 120 of about 7,215,457 (388)

Tandem duplications lead to novel expression patterns through exon shuffling in Drosophila yakuba.

PLoS Genetics, 2017
One common hypothesis to explain the impacts of tandem duplications is that whole gene duplications commonly produce additive changes in gene expression due to copy number changes.
Rebekah L Rogers, Ling Shao, Kevin R Thornton   +2 more
doaj   +1 more source

Multi-faceted analysis provides little evidence for recurrent whole-genome duplications during hexapod evolution

BMC Biology, 2020
Background Gene duplication events play an important role in the evolution and adaptation of organisms. Duplicated genes can arise through different mechanisms, including whole-genome duplications (WGDs).
Dick Roelofs, Arthur Zwaenepoel, Tom Sistermans, Joey Nap, Andries A. Kampfraath, Yves Van de Peer, Jacintha Ellers, Ken Kraaijeveld   +7 more
doaj   +1 more source

Tandem duplication of a genomic region encoding glutathione S-transferase epsilon-2 and -4 genes in DDT-resistant Anopheles stephensi strain from India

Scientific Reports, 2022
The glutathione S-transferases (GST) genes are a multigene family of enzymes involved in the metabolism of endogenous and xenobiotic compounds by catalysing the conjugation of the reduced form of glutathione to the substrate.
Cherry L. Dykes, Gunjan Sharma, Abhisek K. Behera, Neera Kapoor, Mark J. I. Paine, Martin J. Donnelly, Om P. Singh   +6 more
doaj   +1 more source

Host plant-dependent phenotypic reversion of Ralstonia solanacearum from non-pathogenic to pathogenic forms via alterations in the phcA gene [PDF]

, 2003
Ralstonia solanacearum is a plant pathogenic bacterium that undergoes a spontaneous phenotypic conversion (PC) from a wild-type pathogenic to a non-pathogenic form.
Arlat, Mathieu, Barthet, Séverine, Meyer, Damien, Poussier, Stéphane, Thoquet, Philippe, Trigalet Démery, Danièle, Trigalet, André   +6 more
core   +1 more source

Gene duplication and the birthday problem [PDF]

Nature, 1982
Peer Reviewed ; http://deepblue.lib.umich.edu/bitstream/2027.42/62607/1/296176a0 ...
openaire   +3 more sources

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

Molecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris, Vasiliki Siozopoulou, Léon C van Kempen, Anne Sieben, Ella Roelant, Stig Hellemans, Elyne Backx, Laure Sorber, Koen De Winne, Senada Koljenović, Karen Zwaenepoel   +10 more
wiley   +1 more source

Comparative Transcriptome Analyses Reveal Core Parasitism Genes and Suggest Gene Duplication and Repurposing as Sources of Structural Novelty

Molecular biology and evolution, 2014
The origin of novel traits is recognized as an important process underlying many major evolutionary radiations. We studied the genetic basis for the evolution of haustoria, the novel feeding organs of parasitic flowering plants, using comparative ...
Zhenzhen Yang, E. Wafula, L. Honaas, Huiting Zhang, M. Das, M. Fernández-Aparicio, K. Huang, P. Bandaranayake, Biao Wu, J. Der, Christopher R. Clarke, Paula E. Ralph, Lena Landherr, Naomi S. Altman, M. Timko, J. Yoder, J. Westwood, C. dePamphilis   +17 more
semanticscholar   +1 more source

Electrical pulse stimulation reflecting the episodic nature of real‐life exercise modulates metabolic and secretory profile of primary human myotubes

FEBS Open Bio, EarlyView.
Here, we introduced an intermittent electrical stimulation protocol mimicking the episodic nature of real‐life exercise in vitro by alternating low‐ and high‐frequency stimulation. In comparison with widely used continuous stimulation, it enhanced the rate of glucose and fatty acid oxidation, but not the myokine release.
Klára Gabrišová, Tímea Kurdiová, Daria Barkova, Natália Pálešová, Jana Babulicová, Silvia Tyčiaková, Marta Novotová, Mária Balážová, Miroslav Sabo, Václav Pustka, Jozef Ukropec, Barbara Ukropcová   +11 more
wiley   +1 more source

Exonic duplication of the OTC gene by a complex rearrangement that likely occurred via a replication-based mechanism: a case report

BMC Medical Genetics, 2018
Background Ornithine transcarbamylase deficiency (OTCD) is an X-linked recessive disorder involving a defect in the urea cycle caused by OTC gene mutations.
Katsuyuki Yokoi, Yoko Nakajima, Hidehito Inagaki, Makiko Tsutsumi, Tetsuya Ito, Hiroki Kurahashi   +5 more
doaj   +1 more source

Diversification and expression of the PIN, AUX/LAX, and ABCB families of putative auxin transporters in \u3cem\u3ePopulus\u3c/em\u3e [PDF]

, 2012
Intercellular transport of the plant hormone auxin is mediated by three families of membrane-bound protein carriers, with the PIN and ABCB families coding primarily for efflux proteins and the AUX/LAX family coding for influx proteins. In the last decade
Carraro, Nicola, Clouse, Ronald Matthew, Knöller, Anne Sophie, Spicer, Rachel, Tisdale-Orr, Tracy Elizabeth   +4 more
core   +1 more source