Results 161 to 170 of about 7,215,457 (388)
Duplication and MHC linkage of the CTX family of genes inXenopus and in mammals [PDF]
, 1999 Louis Du Pasquier +2 more
openalex +1 more source
Experimental exchange of paralogous domains in the MLH family provides evidence of sub-functionalization after gene duplication [PDF]
, 2021 Christopher M. Furman +4 more
openalex +1 more source
Effectiveness and Safety of Nusinersen and Risdiplam in Spinal Muscular Atrophy: A Systematic Review
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Spinal Muscular Atrophy (SMA) is a rare genetic disorder marked by progressive muscle weakness and mobility loss. It has a profound physical, emotional and social impact on patients and caregivers, requiring comprehensive medical and supportive care.
Amin Mehrabian +9 more
wiley +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective The Gold Coast criteria permit diagnosis of amyotrophic lateral sclerosis (ALS) even without upper motor neuron (UMN) signs. However, whether ALS patients with UMN signs (ALSwUMN) and those without (ALSwoUMN) share similar characteristics and prognoses remains unclear.
Hee‐Jae Jung +7 more
wiley +1 more source
Arthritis Care &Research, EarlyView.Objective Ultrasound (US) has been proposed as a potential tool for assessing skin fibrosis in systemic sclerosis (SSc). However, a large‐scale comparison of US‐based assessment with histologic markers of skin fibrosis has not been reported. We evaluated US‐based skin assessments for their face validity (differentiation between involved SSc and healthy
Ruhani Desai +12 more
wiley +1 more source
Biological applications of the theory of birth-and-death processes [PDF]
, 2005 In this review, we discuss the applications of the theory of birth-and-death processes to problems in biology, primarily, those of evolutionary genomics. The mathematical principles of the theory of these processes are briefly described.
Karev, Georgy P. +2 more
core
Genomes of Ashbya Fungi Isolated from Insects Reveal Four Mating-Type Loci, Numerous Translocations, Lack of Transposons, and Distinct Gene Duplications [PDF]
, 2013 Fred S. Dietrich +3 more
openalex +1 more source
Lung Microphysiological System Validates Novel Cell Therapy for Acute Respiratory Distress Syndrome
Advanced Biology, EarlyView.This study aims to evaluate the efficacy of primed mesenchymal stem cells (pMSCs) as an alternative treatment for Acute Respiratory Distress Syndrome (ARDS), based on a novel lung microphysiological system (MPS) to test the efficacy of pMSCs over the standard treatment, Dexamethasone.
Bokyong Kim +11 more
wiley +1 more source
Differentiation Treatment Applied to Lung Cancer Model Reduces Pathogenic Traits in Vitro
Advanced Biology, EarlyView.Non‐small cell lung cancer cells (A549) treated with a differentiation medium showed strong reduction in proliferation, migration, clonogenicity, spheroid formation and stemness markers, with enhanced adhesion properties and alveolar features, all pointing to a notably less aggressive phenotype in support of differentiation therapy as a promising ...
Alice Grossi +10 more
wiley +1 more source