Results 181 to 190 of about 172,476 (315)

The evolution of bitter taste receptor gene in primates: Gene duplication and selection. [PDF]

Ecol Evol, 2023
Feng P, Liang X, Yu H, Dong X, Liang Q, Dai C.   +5 more
europepmc   +1 more source

Comprehensive Profiling of N6‐methyladnosine (m6A) Readouts Reveals Novel m6A Readers That Regulate Human Embryonic Stem Cell Differentiation

Advanced Science, EarlyView.
This research deciphers the m6A transcriptome by profiling its sites and functional readout effects: from mRNA stability, translation to alternative splicing, across five different cell types. Machine learning model identifies novel m6A‐binding proteins DDX6 and FXR2 and novel m6A reader proteins FUBP3 and L1TD1.
Zhou Huang, Rucong Liu, Zibaguli Wubulikasimu, Wanqing Zhao, Jiaqi Huang, Jiaxuan Wang, Tianyuan Zhang, Rui Fan, Wei Kong, Qinghua Cui, Yang Li, Yuan Zhou   +11 more
wiley   +1 more source

Comparative genomics and expression analysis of polyamine oxidase gene family in Sorghum bicolor reveals functional specialization, gene duplication, and role in drought resilience. [PDF]

BMC Genomics
Ebeed HT.
europepmc   +1 more source

Safety and Efficacy of Adoptive Transfer of Stem Cell Memory Enriched Virus Specific T Cells against CMV and EBV

Advanced Science, EarlyView.
This study finds that CD8⁺ TSCM cells exhibit superior self‐renewal, differentiation, and antiviral activity. Transcriptome and epigenome analyses highlight MAPK cascade regulation in TSCM cells. In vivo, virus‐specific TSCM cells show enhanced persistence and tumor protection.
Xun‐Hong Cao, Xu‐Ying Pei, Yuan‐Yuan Zhang, Juan Xie, Jing‐Wei Tu, Zhuo‐Jun Liu, Yi‐Yang Ding, Chen‐Hua Yan, Yu‐Hong Chen, Yu Wang, Lan‐Ping Xu, Xiao‐Hui Zhang, Xiao‐Jun Huang, Xiang‐Yu Zhao   +13 more
wiley   +1 more source

Identification and Structural Characterization of a Novel COL3A1 Gene Duplication in a Family With Vascular Ehlers-Danlos Syndrome. [PDF]

Mol Genet Genomic Med
Miolo G, Machin P, De Conto M, Fortuna S, Viglio S, Della Puppa L, Geremia S, Corona G.   +7 more
europepmc   +1 more source

Venomous Noodles: The Evolution of Toxins in Nemertea through Positive Selection and Gene Duplication. [PDF]

Toxins (Basel), 2023
Sonoda GG, Tobaruela EC, Norenburg J, Fabi JP, Andrade SCS.   +4 more
europepmc   +1 more source

Divergence in Thermostability of Arabidopsis Mitochondrial Nucleotide Exchange Factors Encoded by Duplicate Genes, MGE1 and MGE2 [PDF]

, 2019
Zih-teng Chen, Meng‐Ju Hung, Shih-Jiun Yu, Tai‐Yan Liao, Yao‐Pin Lin, Rita P.‐Y. Chen, Chien‐Chih Yang, Yee‐yung Charng   +7 more
openalex   +1 more source

PARPi Combining Nanoparticle LIN28B siRNA for the Management of Malignant Ascites

Advanced Science, EarlyView.
This study demonstrates that co‐inhibition of LIN28B and PARP using siLin28b/DSSP@lip‐PEG‐FA nanoparticles in combination with the PARP inhibitor BMN673 effectively suppresses the accumulation of malignant ascites associated with advanced cancers.
Yan Fang, Qian Shen, Yao Lin, Jing Zhu, Xiaolan Zhu, Rui Huang, Yijia Wu, Feiyang Shen, Qian Li, Guopei Zheng, Zhe Zhang, Qian Chu, Junhao Hu, Jianfeng Shen   +13 more
wiley   +1 more source

Protein complexity, gene duplicability and gene dispensability in the yeast genome

, 2006
Yeong‐Shin Lin, Jenn-Kang Hwang, Wen‐Hsiung Li   +2 more
openalex   +1 more source

The Cellular Retinol-Binding Protein Genes Are Duplicated and Differentially Transcribed in the Developing and Adult Zebrafish (Danio rerio) [PDF]

, 2004
Rong‐Zong Liu, Qian Sun, Christine Thisse, Bernard Thisse, Jonathan Wright, Eileen M. Denovan‐Wright   +5 more
openalex   +1 more source