Results 211 to 220 of about 6,867,088 (372)

MOLECULAR GENETIC CHARACTERIZATION OF A LOCUS THAT CONTAINS DUPLICATE Adh GENES IN DROSOPHILA MOJAVENSIS AND RELATED SPECIES [PDF]

, 1986
Leslie E Mills, Philip Batterham, J N Alegre, William T. Starmer, David T. Sullivan   +4 more
openalex   +1 more source

Gene duplication and deletion caused by over-replication at a fork barrier. [PDF]

Nat Commun, 2023
Oehler J, Morrow CA, Whitby MC.
europepmc   +1 more source

Acod1 Promotes PAD4 Ubiquitination via UBR5 Alkylation to Modulate NETosis and Exert Protective Effects in Sepsis

Advanced Science, EarlyView.
In this study, Acod1 knockout in CLP mice significantly increases peripheral blood NET levels, exacerbating inflammation, organ damage, and reducing survival. Further research shows that UBR5 interacts with PAD4, a key NET formation protein. Acod1/itaconate (ITA) enhances the enzymatic activity of UBR5 by alkylating the Cys2768 site, promoting the K48 ...
Huifan Liu, Guoqing Jing, Shujuan Wu, Min Yuan, Yingyue Dong, Xue Chen, Huimin Zhou, Hailong Gong, Jing Zuo, Xiaojing Wu, Xuemin Song   +10 more
wiley   +1 more source

Doubled Duplication of the Structural Gene for Cytosolic Phosphoglucose Isomerase in the Dactylis glomerata L. Polyploid Complex [PDF]

, 1986
R. Lumaret
openalex   +1 more source

Exome Sequencing Reveals the Genetic Architecture of Non‐syndromic Orofacial Clefts and Identifies BOC as a Novel Causal Gene

Advanced Science, EarlyView.
Nonsyndromic orofacial clefts (NSOFCs) are the most common craniofacial defects. Exome sequencing of 214 sporadic cases sheds new light on its genetic architecture and identifies many candidate pathogenic variants. Furthermore, functional studies establish BOC as a novel causal gene and reveal an unusual two‐locus model of inheritance via the epistatic
Qing He, Min Yu, Yuhua Jiao, Yizhu Xu, Xuqin Liang, Wenbin Huang, Linping Xu, Yuxia Hou, Zhanping Ren, Beile Lyu, Zhenwei Qian, Pengpeng Liu, Jing Zhou, Huimei Huang, Chunyan Yin, Huaxiang Zhao, Yi Ding   +16 more
wiley   +1 more source

Evolution by gene duplication and compensatory advantageous mutations.

, 1988
Takehiro Ohta
openalex   +2 more sources

Time for spreading of compensatory mutations under gene duplication. [PDF]

, 1989
Takehiro Ohta
openalex   +1 more source

The role of gene duplication and paralog specialisation in the evolution of the mammalian PRPS complex. [PDF]

Nat Commun
Karki BR, MacMillan AC, Vicente-Muñoz S, Greis KD, Romick LE, Cunningham JT.   +5 more
europepmc   +1 more source

Gene duplication as a major force driving the genome expansion in some giant viruses. [PDF]

J Virol, 2023
Machado TB, Picorelli ACR, de Azevedo BL, de Aquino ILM, Queiroz VF, Rodrigues RAL, Araújo JP, Ullmann LS, Dos Santos TM, Marques RE, Guimarães SL, Andrade ACSP, Gularte JS, Demoliner M, Filippi M, Pereira VMAG, Spilki FR, Krupovic M, Aylward FO, Del-Bem L-E, Abrahão JS.   +20 more
europepmc   +1 more source

IncRNA‐ZFAS1, an Emerging Gate‐Keeper in DNA Damage‐Dependent Transcriptional Regulation

Advanced Science, EarlyView.
LncZFAS1 plays a crucial role during DNA damage response in mammalian cells. Loss of lncZFAS1 results in deficient DNA lesion removal and reduced cell viability. Mechanistically, lncZFAS1 modulates RNAPII phosphorylation and transcription and thereby promotes both GG‐NER and TC‐NER upon UV damage.
Jiena Liu, Qing Lu, Zixuan Fan, Jiahui Lin, Nan He, Xin Zhang, Zhaoya Han, Tingting Zhu, Zhenzhen Wu, Yingying Xu, Yuming Wang   +10 more
wiley   +1 more source