Results 271 to 280 of about 6,833,475 (368)

Towards Molecular Genetics in Clarkia: Gene Duplications and Molecular Characterization of PGI Genes

, 1988
L. D. Gottlieb
openalex   +2 more sources

Following Gene Duplication, Paralog Interference Constrains Transcriptional Circuit Evolution

Science, 2013
Christopher R. Baker, V. Hanson-Smith, A. Johnson   +2 more
semanticscholar   +1 more source

Fn14 Controls the SIRT2‐Mediated Deacetylation of Slug to Inhibit the Metastasis of Epithelial Ovarian Cancer

Advanced Science, EarlyView.
It is reported that Fn14 inhibited EOC metastasis by regulating Slug‐mediated EMT. Furthermore, Fn14 altered the subcellular localization of SIRT2 by interacting with SIRT2, leading to reduced SIRT2 shuttling into the nucleus and subsequently promoting the acetylated degradation of Slug.
Anyue Wu, Shengze Li, Chunyang Feng, Ruiju He, Ruolan Wu, Zhijun Hu, Jinhua Huang, Wenjing Wang, Lei Huang, Lihua Qiu   +9 more
wiley   +1 more source

Multi-gene duplication removal in an engineered human cellular MECP2 duplication syndrome model with an IRAK1-MECP2 duplication. [PDF]

Mol Ther Nucleic Acids
Rizvi SZ, Chan WS, Maino E, Steiman S, Forguson G, Klepfish M, Cohn RD, Ivakine EA.   +7 more
europepmc   +1 more source

Determination of Gene Dosage by a Quantitative Adaptation of the Polymerase Chain Reaction (gd-PCR): Rapid Detection of Deletions and Duplications of Gene Sequences

, 1994
Francesco S. Celi, Maimon M. Cohen, Stylianos E. Antonarakis, Efrat Wertheimer, Jesse Roth, Alan R. Shuldiner   +5 more
openalex   +1 more source

Duplication polymorphism within the third intron of thep53 gene is a rare event in Japanese population [PDF]

, 1994
Keiko Hiyama, Masahiro Takeda, Yoshifumi Shirotani, Shinichi Ishioka, Yukikazu Awaya, Kouki Inai, Kyosuke Inyaku, Soichiro Hozawa, Tsutomu Inamizu, Michio Yamakido   +9 more
openalex   +1 more source

The TET3/GATA6 Axis Drives Lipid Metabolism and Therapeutic Vulnerabilities in Pancreatic Ductal Adenocarcinoma

Advanced Science, EarlyView.
The DNA demethylase TET3 drives lipid metabolic reprogramming in pancreatic ductal adenocarcinoma via a non‐catalytic mechanism. TET3 recruits histone deacetylases to repress GATA6, sustaining lipogenic enzyme expression and ferroptosis resistance.
Shuai Liu, Shaobo Kang, Na Lin, Wenqi Zhang, Shiwen Wang, Yuqing Ren, Xiaofan Ding, Jianxiu Yu, Ruiyu Xie   +8 more
wiley   +1 more source

Tandem gene duplication selected by activation of horizontally transferred gene in bacteria. [PDF]

Appl Microbiol Biotechnol
Zhang F, Shi X, Xu J, Yuan W, Li Z.
europepmc   +1 more source

Targeted gene duplication and disruption for analyzing quantitative genetic traits in mice.

, 1994
O. Smithies, H. S. Kim
openalex   +2 more sources

Ultrarapid drug metabolism: PCR-based detection of CYP2D6 gene duplication [PDF]

, 1998
Linda S. W. Steijns, Jan van der Weide
openalex   +1 more source