Results 71 to 80 of about 7,215,457 (388)
Aggressive prostate cancer is associated with pericyte dysfunction
Molecular Oncology, EarlyView.Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero +11 more
wiley +1 more source
BMC Bioinformatics, 2012 Background Evolutionary methods are increasingly challenged by the wealth of fast growing resources of genomic sequence information. Evolutionary events, like gene duplication, loss, and deep coalescence, account more then ever for incongruence between ...
Górecki Pawel, Eulenstein Oliver
doaj +1 more source
Importance of gene duplication in the evolution of genomic imprinting revealed by molecular evolutionary analysis of the type I MADS-box gene family in Arabidopsis species. [PDF]
PLoS ONE, 2013 The pattern of molecular evolution of imprinted genes is controversial and the entire picture is still to be unveiled. Recently, a relationship between the formation of imprinted genes and gene duplication was reported in genome-wide survey of imprinted ...
Takanori Yoshida, Akira Kawabe
doaj +1 more source
Gene Duplication to Reveal Adaptation Clue of Plant to Environmental Stress: a Case Study of NBS-LRR Genes in Soybean [PDF]
, 2016 Genes responsive to the environmental stresses which are retained after small scale duplication are part of plant genome duplication. However, information of duplicated genes that could be adaptive to environmental changes in plant is limited.
Asadi, N. (nFN) +3 more
core
Landscape of standing variation for tandem duplications in Drosophila yakuba and Drosophila simulans [PDF]
, 2014 We have used whole genome paired-end Illumina sequence data to identify tandem duplications in 20 isofemale lines of D. yakuba, and 20 isofemale lines of D. simulans and performed genome wide validation with PacBio long molecule sequencing. We identify 1,
Andolfatto, Peter +5 more
core +3 more sources
Genome Biology and Evolution, 2015 The evolution of specialized tissues with novel functions, such as the silk synthesizing glands in spiders, is likely an influential driver of adaptive success.
Thomas H. Clarke +4 more
semanticscholar +1 more source
Molecular Oncology, EarlyView.Genetic testing in epithelial ovarian cancer includes both germline and tumor‐testing. This approach often duplicates resources. The current prospective study assessed the feasibility of tumor‐first multigene testing by comparing tumor tissue with germline testing of peripheral blood using an 18‐gene NGS panel in 106 patients.
Elisabeth Spenard +12 more
wiley +1 more source
The shape of human gene family phylogenies
BMC Evolutionary Biology, 2006 Background The shape of phylogenetic trees has been used to make inferences about the evolutionary process by comparing the shapes of actual phylogenies with those expected under simple models of the speciation process.
Cotton James A, Page Roderic DM
doaj +1 more source
Flavonoid Biosynthesis Genes in Triticum aestivum L.: Methylation Patterns in Cis-Regulatory Regions of the Duplicated CHI and F3H Genes [PDF]
, 2022 Ksenia Strygina +1 more
openalex +1 more source
Identifying and removing haplotypic duplication in primary genome assemblies
bioRxiv, 2019 Motivation Rapid development in long read sequencing and scaffolding technologies is accelerating the production of reference-quality assemblies for large eukaryotic genomes.
Dengfeng Guan +5 more
semanticscholar +1 more source