Results 71 to 80 of about 7,565,225 (388)

Antagonistic Roles for KNOX1 and KNOX2 Genes in Patterning the Land Plant Body Plan Following an Ancient Gene Duplication

PLoS Genetics, 2015
Neofunctionalization following gene duplication is thought to be one of the key drivers in generating evolutionary novelty. A gene duplication in a common ancestor of land plants produced two classes of KNOTTED-like TALE homeobox genes, class I (KNOX1 ...
Chihiro Furumizu, J. Alvarez, K. Sakakibara, J. Bowman   +3 more
semanticscholar   +1 more source

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

FEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman, Anna E. Lester, Brian D. Zoltowski   +2 more
wiley   +1 more source

Modes of gene duplication contribute differently to genetic novelty and redundancy, but show parallels across divergent angiosperms. [PDF]

PLoS ONE, 2011
BACKGROUND: Both single gene and whole genome duplications (WGD) have recurred in angiosperm evolution. However, the evolutionary effects of different modes of gene duplication, especially regarding their contributions to genetic novelty or redundancy ...
Yupeng Wang, Xiyin Wang, Haibao Tang, Xu Tan, Stephen P Ficklin, F Alex Feltus, Andrew H Paterson   +6 more
doaj   +1 more source

Clusters of microRNAs emerge by new hairpins in existing transcripts [PDF]

, 2013
Genetic linkage may result in the expression of multiple products from a polycistronic transcript, under the control of a single promoter. In animals, protein-coding polycistronic transcripts are rare.
Alberts, Altschul, Altuvia, Antonio Marco, Aravin, Auyeung, Axtell, Bartel, Bartel, Barton, Baskerville, Blumenthal, Blumenthal, Boutla, Campo-Paysaa, Charlesworth, Cutter, Felsenstein, Griffiths-Jones, Griffiths-Jones, Grimson, Han, Hertel, Hill, Katoh, Kim, Kloosterman, Kozomara, Krol, Lagos-Quintana, Larkin, Lau, Lawrence, Leaman, Lee, Lee, Li, Lynch, Lynch, Maher, Marco, Marco, Marco, Marco, Marco, Maria Ninova, Matthew Ronshaugen, Maynard Smith, Nozawa, Nozawa, Qian, Roux, Ruby, Ryazansky, Saini, Saini, Saitou, Salgado, Sam Griffiths-Jones, Satou, Savard, Sempere, Tamura, Tanzer, Wheeler, Wheeler, Zeng   +66 more
core   +2 more sources

Gene duplication and the evolution of moonlighting proteins

Frontiers in Genetics, 2015
Gene duplication is a recurring phenomenon in genome evolution and a major driving force in the gain of biological functions. Here, we examine the role of gene duplication in the origin and maintenance of moonlighting proteins, with special focus on ...
Adriana Espinosa-Cantú, Diana Ascencio, F. Barona-Gómez, A. DeLuna   +3 more
semanticscholar   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

Algorithms: simultaneous error-correction and rooting for gene tree reconciliation and the gene duplication problem

BMC Bioinformatics, 2012
Background Evolutionary methods are increasingly challenged by the wealth of fast growing resources of genomic sequence information. Evolutionary events, like gene duplication, loss, and deep coalescence, account more then ever for incongruence between ...
Górecki Pawel, Eulenstein Oliver
doaj   +1 more source

Inferring duplication episodes from unrooted gene trees

BMC Genomics, 2018
Background One of evolutionary molecular biology fundamental issues is to discover genomic duplication events and their correspondence to the species tree.
Jarosław Paszek, Paweł Górecki
doaj   +1 more source

Importance of gene duplication in the evolution of genomic imprinting revealed by molecular evolutionary analysis of the type I MADS-box gene family in Arabidopsis species. [PDF]

PLoS ONE, 2013
The pattern of molecular evolution of imprinted genes is controversial and the entire picture is still to be unveiled. Recently, a relationship between the formation of imprinted genes and gene duplication was reported in genome-wide survey of imprinted ...
Takanori Yoshida, Akira Kawabe
doaj   +1 more source

Content based network model with duplication and divergence

, 2005
We construct a minimal content-based realization of the duplication and divergence model of genomic networks introduced by Wagner [A. Wagner, Proc. Natl. Acad. Sci.
Albert, Albert, Ayşe Erzan, Balcan, Banzhaf, Barabasi, Butland, Colizza, Dobrin, Dorogovtsev, Erdös, Erdös, Erdös, Guelzim, Hannon, Harbison, Lee, Lewin, Madan Babu, Maslov, Milo, Mungan, Novina, Pastor-Satorras, Teichmann, Tong, van Noort, Vázquez, Vázquez, Vázquez, Wagner, Wagner, Watson, Watts, Yasemin Şengün   +34 more
core   +1 more source