Results 231 to 240 of about 8,339,405 (403)

The CRISPR-Cas toolbox and gene editing technologies.

Molecules and Cells, 2021
Guanwen Liu, Qiupeng Lin, Shuai Jin, Caixia Gao   +3 more
semanticscholar   +1 more source

Development and validation of PmMAD7 for efficient gene editing in Penaeus monodon. [PDF]

BMC Biotechnol
Huang S, Zhou F, Jiang Z, Jiang S, Yang Q, Yang L, Huang J, Shi J, Ding Y, Li E, Li Y.   +10 more
europepmc   +1 more source

Overexpression of CDT1 inhibits cell cycle progression at S phase by interacting with the mini‐chromosome maintenance complex and causes DNA damage

FEBS Open Bio, EarlyView.
CDT1 is an essential protein for DNA replication licensing that loads the MCM complex, the eukaryotic replicative DNA helicase, onto replication origins. Overexpression of CDT1 induces cell cycle arrest at the S phase. Here we showed CDT1 inhibits the progression of replication forks by interacting with the MCM complex, leading to the stalling and ...
Takashi Tsuyama, Nonoka Takayama, Rina Tanaka, Yuuki Arai, Yohko Yamaguchi, Yuko Nawata, Yutaro Azuma, Shusuke Tada   +7 more
wiley   +1 more source

PP 4.12 – 00141 Enhancement of IL15/IL15RA signaling in immune cells using CRISPR-dCas9-VPR platform

Journal of Virus Eradication, 2022
S. Brancazio, C. Baez, L. Shan, T.H. Burdo, R. Kaminski   +4 more
doaj   +1 more source

Stage- and tissue-specific gene editing using 4-OHT-inducible Cas9 in whole organism. [PDF]

J Cell Biol
Li Y, Zhang W, Wei Z, Li H, Liu X, Zheng T, Aziz T, Xing C, Meng A, Wu X.   +9 more
europepmc   +1 more source

Human Gene Editing [PDF]

, 2021
openaire   +1 more source

Generation of Transgene-Free Semidwarf Maize Plants by Gene Editing of Gibberellin-Oxidase20-3 Using CRISPR/Cas9 [PDF]

, 2020
Jiaojiao Zhang, Xiaofeng Zhang, Rongrong Chen, Li Yang, Kaijian Fan, Yàn Liú, Guoying Wang, Zhenjing Ren, Yunjun Liu, Yunjun Liu, Yunjun Liu   +10 more
openalex   +1 more source

Diabetes‐induced vascular calcification is associated with low pyrophosphate and its oral supplementation prevents calcification in diabetic mice

FEBS Open Bio, EarlyView.
Induction of diabetes in three different mouse strains uniformly resulted in an increase in TNAP activity and a reduction in pyrophosphate (PPi) in the circulation. Inhibition of TNAP restored plasma PPi. Diabetes‐induced calcification in the media layer of the aorta was detected only in the Abcc6−/− strain, which is predisposed to ectopic ...
Krisztina Fülöp, Eszter Kozák, Natália Tőkési, Lilian Kocsis, Anikó Kelemen, Zsuzsanna Geszti, Adriána Kutás, Mariann Harangi, Ágnes Diószegi, Zsolt Rapi, József Balla, Olivier Le Saux, András Váradi, Viola Pomozi   +13 more
wiley   +1 more source

CRISPR and gene editing for kidney diseases: where are we? [PDF]

Clin Kidney J
D'Ambrosio V, Huimei C, Vo N, Siew K, Evans RDR, Freedman B, Pesce F.   +6 more
europepmc   +1 more source

Gene Editing Anxiety

Voices in Bioethics
Photo ID 93567823 © Nataliia Mysik Dreamstime.com Introduction Many parents diagnosed with debilitating anxiety disorders fear their children will suffer from the same psychiatric illness that has plagued their entire lives. While Preimplantation Genetic Diagnosis has long allowed parents to screen out embryos with a predisposition to certain disorders,
openaire   +1 more source