Results 231 to 240 of about 1,009,200 (260)
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Gene Editing for CF

2020
Cystic fibrosis therapeutics have advanced steadily over the past half century, increasing life expectancy from pre-school ages into the fourth and fifth decades of life. New, small molecule pharmacologic therapies that modulate CFTR biosynthesis or activity are proving to be quite effective for many CF patients, indicating that intervention at the ...
openaire   +2 more sources

Improving gene-editing nucleases

Nature Methods, 2012
A flurry of recent papers report refinements to the activity and the assembly of engineered nucleases.
openaire   +3 more sources

A path to efficient gene editing

Nature Medicine, 2018
Signaling by the tumor-suppressor protein p53 antagonizes CRISPR–Cas9 gene editing of human pluripotent stem cells and immortalized human retinal pigment epithelial cells.
openaire   +3 more sources

Ethics of Gene Editing

2019
This is an ethical reflection for students on an issue in gene editing. The case study asks students to reflect on material in the two linked articles. Also included is the grading rubric.
openaire   +2 more sources

Gene-Editing Techniques

2019
This chapter will broadly cover the newest genome editing technology, clustered regularly interspaced short palindromic repeats (CRISPR), and CRISPR-associated system (Cas), as a critical tool for a modern research laboratory. Multiplex gene mutagenesis, tissue-specific gene disruption, DNA insertions, transcriptional activation, transcriptional ...
openaire   +2 more sources

Cancer epigenetics in clinical practice

Ca-A Cancer Journal for Clinicians, 2023
Veronica Davalos, Manel Esteller
exaly  

Debate on Germline Gene Editing

Human Gene Therapy Methods, 2016
Cartier-Lacave N.   +7 more
openaire   +4 more sources

Gene regulation by long non-coding RNAs and its biological functions

Nature Reviews Molecular Cell Biology, 2021
Luisa Statello   +2 more
exaly  

Nanooncology: The future of cancer diagnosis and therapy

Ca-A Cancer Journal for Clinicians, 2013
Sanjiv S Gambhir
exaly  

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