Results 231 to 240 of about 7,473,287 (361)

Gene Editing in <i>Ganoderma lucidum</i>: Development, Challenges, and Future Prospects. [PDF]

J Fungi (Basel)
He S, Liu Y, Zhang Z, Cai M, Hao Y, Hu H.   +5 more
europepmc   +1 more source

HPDL Variant Type Correlates With Clinical Disease Onset and Severity

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Recently, a mitochondrial encephalopathy due to biallelic HPDL variants was described, associated with a broad range of clinical manifestations ranging from severe, infantile‐onset neurodegeneration to adolescence‐onset hereditary spastic paraplegia. HPDL converts 4‐hydroxyphenylpyruvate acid (4‐HPPA) into 4‐hydroxymandelate (4‐HMA),
Eun Hye Lee, Olivia Kim‐Mcmanus, Jennifer H. Yang, Richard Haas, Maha S. Zaki, Ghada M. H. Abdel‐Salam, Yuji Nakamura, Mohamed S. Abdel‐Hamind, Darius Ebrahimi‐Fakhari, Julian E. Alecu, Nicola Brunetti‐Pierri, Varunvenkat M. Srinivasan, Vykuntaraju K. Gowda, Stephanie Gross, Yasemin Alanay, Paria Najarzadeh Totbati, Manya Yadavilli, Liana Friedman, Naomi Meave Ojeda, Joseph G. Gleeson   +19 more
wiley   +1 more source

Gene Editing: An Effective Tool for the Future Treatment of Kidney Disease. [PDF]

J Inflamm Res
Cao ML, Han RY, Chen SD, Zhao DY, Shi MY, Zou JH, Li L, Jiang HK.   +7 more
europepmc   +1 more source

The evolution of RNA editing and pentatricopeptide repeat genes

, 2011
Sota Fujii, Ian Small
openalex   +1 more source

KIF5A p.Pro986Leu Risk Variant and Accelerated Progression of Amyotrophic Lateral Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT This study explored the impact of KIF5A rs113247976 (p.Pro986Leu), a risk allele for amyotrophic lateral sclerosis (ALS), on phenotypic variability in two Italian ALS cohorts (discovery, n = 865; replication, n = 1174). The minor allele (T) frequency was 0.015.
Arianna Manini, Rosario Vasta, Alberto Brusati, Francesco Scheveger, Silvia Peverelli, Alessio Maranzano, Alberto Doretti, Francesco Gentile, Eleonora Colombo, Maura Brunetti, Cristina Moglia, Antonio Canosa, Umberto Manera, Maurizio Grassano, Davide Gentilini, Stefano Messina, Federico Verde, Claudia Morelli, John E. Landers, Bryan J. Traynor, Adriano Chiò, Vincenzo Silani, Andrea Calvo, Antonia Ratti, Nicola Ticozzi   +24 more
wiley   +1 more source

Development of Protoplast-Based Gene Editing System for Areca Palm. [PDF]

Plants (Basel)
Nie H, Batool S, Htwe YM, Fang X, Zhang D, Shi P, Li Z, Ma M, Su H, Yu Q, He X, Wang Y.   +11 more
europepmc   +1 more source

Targeted Editing of Myostatin Gene in Sheep by Transcription Activator-like Effector Nucleases [PDF]

, 2015
Xinxia Zhao, Wei Ni, Chuangfu Chen, Wujiafu Sai, Jun Qiao, Jingliang Sheng, Hui Zhang, Guozhong Li, Dawei Wang, Shengwei Hu   +9 more
openalex   +1 more source

The Impact of Diabetes and Metabolic Syndrome Burden on Pain, Neuropathy Severity and Fiber Type

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Determine the association between diabetes and metabolic syndrome (MetS) burden (number of MetS criteria fulfilled) and pain, neuropathy severity, and fiber type involvement in individuals with established polyneuropathy. Methods The Peripheral Neuropathy Research Registry was queried for individuals with type 1 and type 2 diabetes ...
Long Davalos, Brian C. Callaghan, Lavanya Muthukumar, Simone Thomas, Evan L. Reynolds, A. Gordon Smith, J. Robinson Singleton, Ahmet Höke, Senda Ajroud‐Driss, Mazen M. Dimachkie, Stefanie Geisler, David M. Simpson, PNRR Study Group, Amro M. Stino   +13 more
wiley   +1 more source

Advancing Precision Medicine: Recent Innovations in Gene Editing Technologies. [PDF]

Adv Sci (Weinh)
Koodamvetty A, Thangavel S.
europepmc   +1 more source

"The Ecology of Plant Secondary Metabolites: From Genes to Global Processes" edited by G. Iason et al. 2012. [book review]

, 2012
William J. Crins
openalex   +2 more sources