Results 271 to 280 of about 7,473,287 (361)

The Potential for Extracellular Vesicles in Nanomedicine: A Review of Recent Advancements and Challenges Ahead

Advanced Biology, EarlyView.
Extracellular vesicles (EVs) play a dual role in diagnostics and therapeutics, offering innovative solutions for treating cancer, cardiovascular, neurodegenerative, and orthopedic diseases. This review highlights EVs’ potential to revolutionize personalized medicine through specific applications in disease detection and treatment.
Farbod Ebrahimi, Anjali Kumari, Samaneh Ghadami, Saqer Al Abdullah, Kristen Dellinger   +4 more
wiley   +1 more source

A CRISPR Cas12a/Cpf1 strategy to facilitate robust multiplex gene editing in Aspergillus Niger. [PDF]

Fungal Biol Biotechnol
van Esch AP, Prudence SMM, Contesini FJ, Gerhartz B, Royle KE, Mortensen UH.   +5 more
europepmc   +1 more source

RhoA and Rac1 as Mechanotransduction Mediators in Colorectal Cancer

Advanced Biology, EarlyView.
Analysing RhoA and Rac1 protein levels in Colorectal cancer (CRC) samples under mechanical strain highlights their potential as diagnostic markers. Monitoring their activity could offer valuable insights into how cancer spreads, paving the way for new approaches to better understand and diagnose colorectal cancer.
Sharda Yadav, Sanjaya KC, Mark A. T. Blaskovich, Cu‐tai Lu, Alfred K Lam, Nam‐Trung Nguyen   +5 more
wiley   +1 more source

PP 2.17 – 00187 Myeloid-derived extracellular vesicle production is upregulated with SHIV.D infection

Journal of Virus Eradication, 2022
R. Podgorski, R. Warfield, J.A. Robinson, K.J. Bar, T.H. Burdo   +4 more
doaj  

Gene editing toward the use of autologous therapies in recessive dystrophic epidermolysis bullosa

, 2015
Christopher Perdoni, Mark J. Osborn, Jakub Tolar   +2 more
openalex   +2 more sources

Using a Supramolecular Approach to Engineer Modular Hydrogel Platforms for Culturing Protoplasts – from General Tissue Engineering to Cellular Agriculture

Advanced Biology, EarlyView.
Using supramolecular monomers, various hydrogel culture systems were formulated to culture protoplasts; including 2D, 2.5D, and 3D hydrogels. Depending on the culture platform, bioactive functionalization led to protoplast enlargement (2D and 2.5D) or plasmolysis (3D). This work shows the potential to modularly engineer synthetic platforms for cellular
Maritza M. Rovers, Erik J. Slootweg, Ferdinand C. O. Los, Patricia Y. W. Dankers   +3 more
wiley   +1 more source

PP 4.12 – 00141 Enhancement of IL15/IL15RA signaling in immune cells using CRISPR-dCas9-VPR platform

Journal of Virus Eradication, 2022
S. Brancazio, C. Baez, L. Shan, T.H. Burdo, R. Kaminski   +4 more
doaj  

Harnessing promoter elements to enhance gene editing in plants: perspectives and advances. [PDF]

Plant Biotechnol J
Gondalia N, Quiroz LF, Lai L, Singh AK, Khan M, Brychkova G, McKeown PC, Chatterjee M, Spillane C.   +8 more
europepmc   +1 more source

Murine Models and Human Cell Line Models to Study Altered Dynamics of Ovarian Follicles in Polycystic Ovary Syndrome

Advanced Biology, EarlyView.
The manuscript examines preclinical murine and human models to study polycystic ovary syndrome (PCOS), delving into the cellular and molecular mechanisms underlying altered ovarian follicular dynamics. It explores the cellular interactions involved in normal and PCOS ovaries and outlines the current and novel strategies in the search for preclinical ...
Arturo Bevilacqua, Cristiano Giuliani, Giovanna Di Emidio, Samuel H Myers, Vittorio Unfer, Carla Tatone   +5 more
wiley   +1 more source

Engineering tripartite gene editing machinery for highly efficient non-viral targeted genome integration. [PDF]

Nat Commun
Nam H, Xie K, Majumdar I, Wang J, Yang S, Starzyk J, Lee D, Shan R, Li J, Wu H.   +9 more
europepmc   +1 more source