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Gene Expression Commons: an open platform for absolute gene expression profiling. [PDF]
, 2012 Gene expression profiling using microarrays has been limited to comparisons of gene expression between small numbers of samples within individual experiments.
Bhattacharya, Deepta +9 more
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Comparative Enumeration Gene Expression [PDF]
, 2008 This paper is about differential gene expression measured by transcript counting methods such as SAGE or MPSS. It introduces two significance tests for detection of differential expressed tags: frequentist and Bayesian. Under the frequentist view, it is
Carlos A. D. E. B. Pereira +1 more
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Gene expression tomography [PDF]
Physiological Genomics, 2002 Gene expression tomography, or GET, is a new method to increase the speed of three-dimensional (3-D) gene expression analysis in the brain. The name is evocative of the method’s dual foundations in high-throughput gene expression analysis and computerized tomographic image reconstruction, familiar from techniques such as positron emission tomography ...
BROWN, VANESSA M +6 more
openaire +5 more sources
Disruption of ATRX-RNA interactions uncovers roles in ATRX localization and PRC2 function
Nature Communications, 2020 ATRX is an RNA binding protein that mediates targeting of polycomb repressive complex 2 (PRC2) to genomic sites. Here the authors identify the RNA binding region and show that the RNA binding is required for ATRX localization and for its recruitment of ...
Wenqing Ren +11 more
doaj +1 more source
Scientific Reports, 2021 A promising therapy for patients with B-cell lymphoma is based on vaccination with idiotype monoclonal antibodies (mAbs). Since idiotypes are different in each tumor, a personalized vaccine has to be produced for each patient.
Erkuden Casales +11 more
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Wellcome Open Research, 2018 Background: Viral oncogenes and mutated proto-oncogenes are potent drivers of cancer malignancy. Downstream of the oncogenic trigger are alterations in protein properties that give rise to cellular transformation and the acquisition of malignant cellular
Tony Ly +6 more
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Nature, 2019 This version of the article has been accepted for publication, after peer review (when applicable) and is subject to Springer Nature's AM terms of use, but is not the Version of Record and does not reflect post-acceptance improvements, or any corrections.
Nikos Karaiskos +5 more
openaire +5 more sources
Expression of Green Fluorescence Protein (GFP) in Zebrafish Muscle through Injection: A Gene Therapy Model [PDF]
, 2008 Expression of the target gene is important for gene therapy. Presently, localized transgenesis is used for gene therapy which can be achieved by a target gene expression. Here, we have reported the plasmid mediated gene therapy to zebrafish model.
C. H. Hsu +4 more
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GC content of vertebrate exome landscapes reveal areas of accelerated protein evolution
BMC Evolutionary Biology, 2019 Background Rapid accumulation of vertebrate genome sequences render comparative genomics a powerful approach to study macro-evolutionary events. The assessment of phylogenic relationships between species routinely depends on the analysis of sequence ...
R. Huttener +6 more
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Temporal inhibition of chromatin looping and enhancer accessibility during neuronal remodeling
Nature Communications, 2021 Long-range looping of an enhancer to a promoter (E-P looping) is a key feature of gene activation; thus, regulation of E-P looping could serve as an effective strategy to precisely control gene expression.
Dahong Chen +4 more
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