Results 11 to 20 of about 4,531,065 (206)

Gene expression in large pedigrees: analytic approaches. [PDF]

, 2016
BackgroundWe currently have the ability to quantify transcript abundance of messenger RNA (mRNA), genome-wide, using microarray technologies. Analyzing genotype, phenotype and expression data from 20 pedigrees, the members of our Genetic Analysis ...
Cantor, Rita M, Cordell, Heather J
core   +1 more source

Engineering stochasticity in gene expression [PDF]

, 2008
Stochastic fluctuations (noise) in gene expression can cause members of otherwise genetically identical populations to display drastically different phenotypes. An understanding of the sources of noise and the strategies cells employ to function reliably
Bayer, Travis S., Ellington, Andrew D., Levy, Matthew, Simpson, Zachary B., Tabor, Jeffrey J.   +4 more
core   +1 more source

Positive selection underlies Faster-Z evolution of gene expression in birds. [PDF]

, 2015
The elevated rate of evolution for genes on sex chromosomes compared to autosomes (Fast-X or Fast-Z evolution) can result either from positive selection in the heterogametic sex, or from non-adaptive consequences of reduced relative effective population ...
Dean, R, Harrison, PW, Mank, JE, Wright, AE, Zimmer, F   +4 more
core   +1 more source

Watching gene expression in color. [PDF]

, 2019
A combination of two fluorescent proteins with different half-lives allows gene expression to be followed with improved time ...
Bates, Borok, Cachero, Dana, Doe, He, Lee, Lin, Pfeiffer, Royer, St Johnston   +10 more
core   +2 more sources

Modeling dependent gene expression

, 2012
In this paper we propose a Bayesian approach for inference about dependence of high throughput gene expression. Our goals are to use prior knowledge about pathways to anchor inference about dependence among genes; to account for this dependence while ...
Freedman, Ralph S., Müller, Peter, Parmigiani, Giovanni, Telesca, Donatello   +3 more
core   +1 more source

The Effect of Transposable Element Insertions on Gene Expression Evolution in Rodents [PDF]

, 2009
Background:Many genomes contain a substantial number of transposable elements (TEs), a few of which are known to be involved in regulating gene expression.
A Nekrutenko, A Smit, Adam Eyre-Walker, AI Su, AO Urrutia, B McClintock, B-Y Liao, C Feschotte, CB Lowe, David Enard, G Bejerano, I. King Jordan, IK Jordan, J Brosius, JC Silva, JR Walker, JS Han, JS Han, L Marino-Ramirez, LA Pennacchio, LN van de Lagemaat, M Kamal, P Khaitovich, P Medstrand, PD Keightley, RA Irizarry, RC Gentleman, RJ Britten, RJ Britten, RM Kuhn, TJ Hubbard, TS Mikkelsen, V Pereira, Vini Pereira, W Enard, W Makalowski, X Xie   +36 more
core   +8 more sources

Effects of chronic browsing on life‐history traits of an irruptive large herbivore population

Population Ecology, EarlyView.
This study aimed to determine the relationship between diet quality, body mass, and size (hind foot length), and female reproduction and sought to identify the mechanism by which high density under severe food limitations is maintained. Our results demonstrated that sika deer introduced to Nakanoshima Island have maintained high densities through high ...
Koichi Kaji, Kazutaka M. Takeshita, Hiroshi Takahashi, Hiromasa Igota, Mayumi Ueno, Yukiko Matsuura, Takashi Ikeda, Ryo Yoshizawa, Hino Takafumi, Tsuyoshi Yoshida   +9 more
wiley   +1 more source

Origins of Binary Gene Expression in Post-transcriptional Regulation by MicroRNAs

, 2012
MicroRNA-mediated regulation of gene expression is characterised by some distinctive features that set it apart from unregulated and transcription factor-regulated gene expression. Recently, a mathematical model has been proposed to describe the dynamics
Bose, Indrani, Ghosh, Sayantari
core   +1 more source

Digital gene expression analysis of the zebra finch genome [PDF]

, 2010
Background: In order to understand patterns of adaptation and molecular evolution it is important to quantify both variation in gene expression and nucleotide sequence divergence.
Balakrishnan, C.N., Burke, T., Ekblom, R., Slate , J.   +3 more
core   +4 more sources

Dendritic cells steering antigen and leukocyte traffic in lymph nodes

FEBS Letters, EarlyView.
Dendritic cells are key players in the activation of T cells and their commitment to effector function. In this In a Nutshell Review, we will discuss how dendritic cells guide the trafficking of antigen and leukocytes in the lymph node, thus influencing T‐cell activation processes. Dendritic cells (DCs) play a central role in initiating and shaping the
Enrico Dotta, Agnieszka Katarzyna Maciola, Tania Baccega, Giulia Pasqual   +3 more
wiley   +1 more source