Results 21 to 30 of about 5,466,172 (305)

The HSV-1 Latency-Associated Transcript Functions to Repress Latent Phase Lytic Gene Expression and Suppress Virus Reactivation from Latently Infected Neurons [PDF]

open access: yes, 2016
open access articleHerpes simplex virus 1 (HSV-1) establishes life-long latent infection within sensory neurons, during which viral lytic gene expression is silenced.
Coleman, Heather M.   +7 more
core   +3 more sources

Genome‐wide allele‐ and strand‐specific expression profiling

open access: yesMolecular Systems Biology, 2009
Recent reports have shown that most of the genome is transcribed and that transcription frequently occurs concurrently on both DNA strands. In diploid genomes, the expression level of each allele conditions the degree to which sequence polymorphisms ...
Julien Gagneur   +5 more
doaj   +1 more source

Localization and Functional Roles of Components of the Translation Apparatus in the Eukaryotic Cell Nucleus

open access: yesCells, 2021
Components of the translation apparatus, including ribosomal proteins, have been found in cell nuclei in various organisms. Components of the translation apparatus are involved in various nuclear processes, particularly those associated with genome ...
Zaur M. Kachaev   +4 more
doaj   +1 more source

A microfluidic processor for gene expression profiling of single human embryonic stem cells [PDF]

open access: yes, 2008
The gene expression of human embryonic stem cells (hESC) is a critical aspect for understanding the normal and pathological development of human cells and tissues.
Chen, Yan   +6 more
core   +1 more source

Characterization of RNA in exosomes secreted by human breast cancer cell lines using next-generation sequencing [PDF]

open access: yesPeerJ, 2013
Exosomes are nanosized (30–100 nm) membrane vesicles secreted by most cell types. Exosomes have been found to contain various RNA species including miRNA, mRNA and long non-protein coding RNAs. A number of cancer cells produce elevated levels of exosomes.
Piroon Jenjaroenpun   +5 more
doaj   +2 more sources

Gene Therapy for Acquired and Genetic Cholestasis

open access: yesBiomedicines, 2022
Cholestatic diseases can be caused by the dysfunction of transporters involved in hepatobiliary circulation. Although pharmacological treatments constitute the current standard of care for these diseases, none are curative, with liver transplantation ...
Javier Martínez-García   +4 more
doaj   +1 more source

Impact of the sickle mutant and temperature on the structure of transcripts and RNAs from Arabidopsis thaliana

open access: yesBMC Research Notes, 2022
Objectives The objective of this data set was to identify how interaction between temperature and the sickle-3 (sic-3) mutant alters the global messenger RNA (mRNA) content of Arabidopsis thaliana seedlings.
Carine M. Marshall, Frank G. Harmon
doaj   +1 more source

Positive selection underlies Faster-Z evolution of gene expression in birds. [PDF]

open access: yes, 2015
The elevated rate of evolution for genes on sex chromosomes compared to autosomes (Fast-X or Fast-Z evolution) can result either from positive selection in the heterogametic sex, or from non-adaptive consequences of reduced relative effective population ...
Dean, R   +4 more
core   +1 more source

Genetic Variation and Antioxidant Response Gene Expression in the Bronchial Airway Epithelium of Smokers at Risk for Lung Cancer [PDF]

open access: yes, 2010
Prior microarray studies of smokers at high risk for lung cancer have demonstrated that heterogeneity in bronchial airway epithelial cell gene expression response to smoking can serve as an early diagnostic biomarker for lung cancer.
Bell, Douglas A.   +7 more
core   +13 more sources

Identification of common oncogenic and early developmental pathways in the ovarian carcinomas controlling by distinct prognostically significant microRNA subsets

open access: yesBMC Genomics, 2017
Background High-grade serous ovarian carcinoma (HG-SOC) is the dominant tumor histologic type in epithelial ovarian cancers, exhibiting highly aberrant microRNA expression profiles and diverse pathways that collectively determine the disease ...
Vladimir A. Kuznetsov   +2 more
doaj   +1 more source

Home - About - Disclaimer - Privacy