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This contribution is based on the four presentations made at the Special Interest Group (SIG) meeting titled Gene Expression in Fungi held during IMC9 in Edinburgh. This overview is independent from other articles published or that will be published by each speaker.
KALKANCI, AYŞE+3 more
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Zipf's Law in Gene Expression [PDF]
Using data from gene expression databases on various organisms and tissues, including yeast, nematodes, human normal and cancer tissues, and embryonic stem cells, we found that the abundances of expressed genes exhibit a power-law distribution with an ...
G. K. Zipf+5 more
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Establishment of human iPSC-based models for the study and targeting of glioma initiating cells
Glioma can originate from the transformation of neural progenitor cells into glioma initiating cells. Here, the authors demonstrate the use of induced pluripotent stem cells as a suitable model for generating neural progenitor cells, which can be ...
Ignacio Sancho-Martinez+22 more
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Generalized gene co-expression analysis via subspace clustering using low-rank representation [PDF]
BACKGROUND: Gene Co-expression Network Analysis (GCNA) helps identify gene modules with potential biological functions and has become a popular method in bioinformatics and biomedical research.
Huang, Kun, Wang, Tongxin, Zhang, Jie
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Lentiviral vectors with amplified beta cell-specific gene expression. [PDF]
An important goal of gene therapy is to be able to deliver genes, so that they express in a pattern that recapitulates the expression of an endogenous cellular gene.
Crooks, GM+7 more
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Expression quantitative trait loci are highly sensitive to cellular differentiation state [PDF]
Blood cell development from multipotent hematopoietic stem cells to specialized blood cells is accompanied by drastic changes in gene expression for which the triggers remain mostly unknown.
A Gerrits+48 more
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Components of the translation apparatus, including ribosomal proteins, have been found in cell nuclei in various organisms. Components of the translation apparatus are involved in various nuclear processes, particularly those associated with genome ...
Zaur M. Kachaev+4 more
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Genome‐wide allele‐ and strand‐specific expression profiling
Recent reports have shown that most of the genome is transcribed and that transcription frequently occurs concurrently on both DNA strands. In diploid genomes, the expression level of each allele conditions the degree to which sequence polymorphisms ...
Julien Gagneur+5 more
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Sequencing refractory regions in bird genomes are hotspots for accelerated protein evolution
Background Approximately 1000 protein encoding genes common for vertebrates are still unannotated in avian genomes. Are these genes evolutionary lost or are they not yet found for technical reasons?
R. Huttener+11 more
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Gene expression in large pedigrees: analytic approaches. [PDF]
BackgroundWe currently have the ability to quantify transcript abundance of messenger RNA (mRNA), genome-wide, using microarray technologies. Analyzing genotype, phenotype and expression data from 20 pedigrees, the members of our Genetic Analysis ...
Cantor, Rita M, Cordell, Heather J
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