Results 161 to 170 of about 2,019,582 (297)

Extensive differential gene expression and regulation by sex in human skeletal muscle. [PDF]

Cell Genom
Hanks SC, Mauger AS, Varshney A, Ciotlos DL, Manickam N, Narisu N, Shumway AJ, Orchard P, Erdos MR, Sweeney MD, Okamoto J, Jackson AU, Stringham HM, Bonnycastle LL, Zhou X, Lakka TA, Mohlke KL, Tuomilehto J, Laakso M, Boehnke M, Sethupathy P, Collins FS, Koistinen HA, Parker SCJ, Scott LJ.   +24 more
europepmc   +1 more source

Rolling Circle Mutagenesis of GST-mCherry to Understand Mutation, Gene Expression, and Regulation. [PDF]

J Microbiol Biol Educ, 2017
Cole J, Ferguson A, Segarra VA, Walsh S.
europepmc   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

Apolipoprotein B gene expression and regulation in relation to Alzheimer's disease pathophysiology. [PDF]

J Lipid Res
Aumont-Rodrigue G, Picard C, Labonté A, Poirier J.   +3 more
europepmc   +1 more source

Gene expression dosage regulation in an allopolyploid fish. [PDF]

PLoS One, 2015
Matos I, Machado MP, Schartl M, Coelho MM.   +3 more
europepmc   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

Molecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang, Hyung Seok Kim, Geum Ok Baek, Moon Gyeong Yoon, Su In Lee, Jee‐Yeong Jeong, Ji Eun Han, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun   +9 more
wiley   +1 more source

Exploring the Fanconi Anemia Gene Expression and Regulation by MicroRNAs in Gilthead Seabream (Sparus aurata) at Different Gonadal Development Stages. [PDF]

Mar Biotechnol (NY)
Papadaki M, Le NS, Mylonas CC, Sarropoulou E.   +3 more
europepmc   +1 more source

Computing and Applying Atomic Regulons to Understand Gene Expression and Regulation. [PDF]

Front Microbiol, 2016
Faria JP, Davis JJ, Edirisinghe JN, Taylor RC, Weisenhorn P, Olson RD, Stevens RL, Rocha M, Rocha I, Best AA, DeJongh M, Tintle NL, Parrello B, Overbeek R, Henry CS.   +14 more
europepmc   +1 more source

Translating whole‐genome doubling into precision medicine in cancer

Molecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source