Results 161 to 170 of about 1,893,955 (220)

Transcriptomic regulation of pancreatic acinar cell homeostasis and plasticity. [PDF]

open access: yesBiochem Soc Trans
Zhang X   +5 more
europepmc   +1 more source

Regulated Gene Expression in Gene Therapy

Annals of the New York Academy of Sciences, 2001
Abstract: The original model of gene therapy, that of efficient delivery, durable transfer, and stable expression of transgenes to correct a gene defect underlying an inherited disease, is limited in light of improved understanding of the processes involved.
P W, Zoltick, J M, Wilson
openaire   +2 more sources

Ploidy Regulation of Gene Expression

Science, 1999
Microarray-based gene expression analysis identified genes showing ploidy-dependent expression in isogenic Saccharomyces cerevisiae strains that varied in ploidy from haploid to tetraploid. These genes were induced or repressed in proportion to the number of chromosome sets, regardless of the mating type.
T, Galitski   +4 more
openaire   +2 more sources

Regulation of histone gene expression

Current Opinion in Cell Biology, 1992
Histone genes are expressed during the S phase of the cell cycle. Control is at multiple levels and is mediated by the integration of regulatory signals in response to cell-cycle progression and the onset of differentiation. Much work has been carried out on the H4 gene promoter, which appears to be organized into a series of distinct regulatory ...
Stein, Gary S.   +3 more
openaire   +3 more sources

Regulation of Gene Expression

New England Journal of Medicine, 1994
Genetics is a language with rules of composition that give the tissues of the body their special traits. These rules govern the activation of particular subgroups of genes, which determine not only the unique characteristics of a cell type but also whether it remains quiescent, divides, or dies. The timing of gene activation is very important. If genes
openaire   +2 more sources

Regulation of gene expression

British Medical Bulletin, 1991
A fundamental tenet of biology is that the phenotype of an organism is ultimately determined by its complement of genes. In multicellular organisms, it is the regulated pattern of expression of genes which determines the proliferation and differentiation of individual cell lineages and hence establishes the adult phenotype.
openaire   +2 more sources

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