Results 151 to 160 of about 638,559 (231)

Regulation of ER Stress-Associated Gene Expression by Lifeguard in Human Breast Cancer Cells. [PDF]

Cancer Rep (Hoboken)
Nebel I, Strauß S, Schlottmann F, Herrmann LM, Vogt PM, Bucan V.   +5 more
europepmc   +1 more source

The Regulatory Role and Mechanism of Myoferlin in Mitophagy During Papillary Thyroid Carcinogenesis

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Papillary thyroid carcinoma (PTC) is the most prevalent subtype of thyroid cancer; however, the regulatory mechanisms by which mitophagy influences its progression remain inadequately elucidated. This study sought to examine the role of myoferlin (MYOF) in mitophagy and its molecular basis during PTC development. Utilizing three paired PTC and
Wen‐Chao Lyu, Yang‐Shuai Wang, Chun‐Yang Shang, Ming Qi, Tong‐Chang Li, Li‐Xin Lian, Hai‐Quan Qiao   +6 more
wiley   +1 more source

Understanding the Epigenetic Landscape of Barrett's Esophagus and Esophageal Cancer: A Review of Current Findings, Caveats and Future Directions. [PDF]

Genes Chromosomes Cancer
Lawless L, Doherty T, Surlis C, Gilmartin N, Murphy TM.   +4 more
europepmc   +1 more source

DARS2 Promotes Tumorigenesis and Metastasis by Activating PI3K/Akt/GSK‐3β/β‐Catenin Signaling Pathway in Breast Cancer

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Aspartyl‐tRNA synthetase 2 (DARS2), the mitochondrial enzyme responsible for aminoacylation of aspartyl‐tRNA, is traditionally known for its effect on protein synthesis. Recently, DARS2 is reported to be implicated in tumorigenesis. However, its specific effect on breast cancer (BC) is poorly understood.
Na Wang, Ming Huang
wiley   +1 more source

Triptolide Suppresses Tongue Squamous Cell Carcinoma Progression via PI3K–AKT Pathway Inhibition: An Integrative Network Pharmacology and Experimental Validation Study

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Tongue squamous cell carcinoma, the most aggressive subtype of oral squamous cell carcinoma, which is associated with high mortality, frequent recurrence, and early lymph‐node metastasis. Triptolide, a bioactive diterpenoid from Tripterygium wilfordii, exhibits broad anticancer activity.
Shan‐Shan Wang, Hong‐Cheng Wei, Lin Jiang, Yi‐Sen Shao   +3 more
wiley   +1 more source

RIOK2 Promotes Clear Cell Renal Cell Carcinoma Progression Through Cell Cycle Regulation. [PDF]

Cancer Med
Shikuma H, Goto K, Shimo A, Hatayama T, Yukihiro K, Iwane K, Yamanaka R, Tasaka R, Kohada Y, Takemoto K, Kobatake K, Sekino Y, Kitano H, Goriki A, Hieda K, Kaminuma O, Hinata N.   +16 more
europepmc   +1 more source

Analysis of Carbohydrates and Glycoconjugates by Matrix‐Assisted Laser Desorption/Ionization Mass Spectrometry: An Update for 2023–2024

Mass Spectrometry Reviews, EarlyView.
ABSTRACT The use of MALDI mass spectrometry for the analysis of carbohydrates and glycoconjugates is a well‐established technique and this comprehensive review is the twelfth update of the original article published in 1999 and brings coverage of the literature to the end of 2024.
David J. Harvey
wiley   +1 more source

p53 in Canine Mammary Tumors: From Molecular Pathogenesis to Biomarker Applications and Comparative Oncology. [PDF]

Vet Sci
Wang Z, Qin Y, Zeng Y, Liao S, Tao X, Liu X.   +5 more
europepmc   +1 more source

The FGF/FGFR System in the Biology and Therapeutic Landscape of Pediatric CNS Tumors

Medicinal Research Reviews, EarlyView.
ABSTRACT Central nervous system (CNS) tumors are the most common solid malignancies in children, comprising a highly heterogeneous group of neoplasms defined by distinct molecular alterations and clinical behaviors. Advances in molecular genetics have underscored the relevance of specific signaling pathways in driving pediatric tumorigenesis, among ...
Serena Filiberti, Camilla Tavani, Elena Somenza, Nicolas Tassone, Antonio d'Amati, Marta Turati, Roberto Ronca   +6 more
wiley   +1 more source

Identification of Survival-Associated miRNA Signatures in Glioblastoma Using Next-Generation Sequencing. [PDF]

Noncoding RNA
Bakó A, Torner B, Géczi D, Penyige A, Pozsgai P, Birkó Z, Klekner Á.   +6 more
europepmc   +1 more source