Results 171 to 180 of about 7,007,953 (262)

DNA Methylation and Transcriptomic Profiles of Wilms Tumour Reveal New Deregulated Genes and Epigenetic Processes Relevant for Tumour Stratification and Management

International Journal of Cancer, EarlyView.
ABSTRACT Wilms Tumour (WT), the most common kidney cancer in children, presents features of altered kidney development and frequently exhibits molecular alterations at the 11p15.5 imprinted locus, affecting the IGF2 and H19 genes, which contribute to tumour growth and predisposition.
Abu Saadat, Francesco Cecere, Federica Rossetti, Laura Pignata, Emilia D'Angelo, Carlo Giaccari, Gaetano Verde, Paola Quarello, Franca Fagioli, Josep Roma, Manel Esteller, Enrique de Álava, Flavia Cerrato, Andrea Riccio, Angela Sparago   +14 more
wiley   +1 more source

A Comparative Analysis of the Methylation Status of Non-Coding RNA Promoters in Fibroid and Matched Myometrium. [PDF]

Int J Mol Sci
Chuang TD, Rysling S, Wiseman A, Alfaro G, Jahromi SP, Jahromi SP, Baghdasarian D, Khorram O.   +7 more
europepmc   +1 more source

Human biomarker navigator

iMeta, EarlyView.
The Human Biomarker Navigator integrates the disease continuum, biomarker dynamics, cross‐organ biomarker networks, biomarker classification, and technology‐driven paradigms. It maps how biomarkers link multi‐system physiology and pathology across the nervous, respiratory, endocrine, circulatory, immune, digestive, urinary, reproductive, and ...
Meng‐Yao Li, Qian Zhang, Zijie Wang, Zeping Gui, Jing Liu, Jingda Li, Maojun Jiang, Zukang Chang, Qingqing Han, Bendong Yang, Tariq Saeed, Jun Li, Jinghan Jia, Chenghu Song, Tong Shao, Tianhuan Peng, Xueying Zhang, Pingping Guo, Jun Luo, Gangao Yang, Yuan Wan, Gokhan Zengin, Quan Yuan, Lingru Li, Xiaohui Fan, Yang Luo, Lvyun Zhu, Yanfei Zheng, Wenjun Mao, Wenlong Sun   +29 more
wiley   +1 more source

MTA2: Decoding pathogenic mechanisms, clinical implications and therapeutic frontiers across disease landscapes (Review). [PDF]

Int J Mol Med
Xie H, Chen L, Gou J, Long X, Yang Y, Hu H, Wu P, Yan Q, Wu Y.   +8 more
europepmc   +1 more source

The T‐Cell Response Mechanism in Human Papillomavirus‐Associated Cervical Cancer and New Strategies for Immunotherapy

iNew Medicine, EarlyView.
ABSTRACT Human papillomavirus (HPV) is a double‐stranded DNA virus that infects human skin and mucosal tissues exclusively. The German scientist Harald zur Hausen was awarded the 2008 Nobel Prize in Physiology or Medicine for his discovery of the link between HPV infection and cervical cancer.
Fang Zhu, Farah Nazir, Ying Zhou, Yuhua Shang, Hongliang He, Tengchuan Jin   +5 more
wiley   +1 more source

Network-based integrative analysis of multi-level regulatory mechanisms associated with glyphosate exposure. [PDF]

Front Bioinform
Consuegra-Mayor C, Arroyo-Salgado B, Olivero-Verbel J.   +2 more
europepmc   +1 more source

Ovarian Cancer: Epidemiology, Disease Mechanisms, New Diagnosis and Treatment Strategies, and Research Directions

iNew Medicine, EarlyView.
ABSTRACT Ovarian cancer (OC) continues to be the deadliest gynecological malignancy and a significant cause of cancer‐related mortality among women worldwide. Standard treatment strategies typically entail platinum‐based chemotherapy in conjunction with cytoreductive surgery.
Zunera Khalid, Weirong Fan, Farah Nazir, Yixiang Xing, Tengchuan Jin   +4 more
wiley   +1 more source

Molecular Mechanisms of Tumor Pathogenesis. [PDF]

Cells
Lavoro A, Candido S.
europepmc   +1 more source

Bisphenol A Induces DNA Damage and Differential Cytotoxicity in Thyroid Cells: High‐Dose Effects Challenge Regulatory Thresholds

Journal of Applied Toxicology, EarlyView.
ABSTRACT Bisphenol A (BPA), a ubiquitous environmental endocrine disruptor, has been implicated in carcinogenesis; however, its effects on thyroid cells remain unclear. This study investigated BPA‐induced cytotoxicity and genotoxicity in thyroid cell lines, including normal follicular (Nthy‐ori 3‐1), papillary carcinoma (TPC‐1 and BCPAP) and anaplastic
Izabela Fernanda Dal' Bó, Natássia Elena Bufalo, Valdemar Máximo, Laura Sterian Ward   +3 more
wiley   +1 more source

Dark matter matters: from noncoding RNA regulation to cancer immunity. [PDF]

Oncoimmunology
Lteif M, Hijazi A, Morgand E, Van den Eynde M, Salzet M, Galon J.   +5 more
europepmc   +1 more source