Results 171 to 180 of about 668,253 (275)

Left ventricular diastolic dysfunction worsens prognosis in patients with heart failure due to dilated cardiomyopathy

ESC Heart Failure, Volume 12, Issue 2, Page 1183-1193, April 2025.
Abstract Aims The prognostic significance of left ventricular (LV) diastolic dysfunction (LVDD) severity in patients with dilated cardiomyopathy (DCM) remains uncertain. This study aimed to evaluate the association of LVDD severity and elevated left atrial pressure (eLAP) with patient outcomes in stable, non‐acutely decompensated patients with DCM ...
Mateusz Winiarczyk, Ewa Dziewięcka, Sylwia Wiśniowska‐Śmiałek, Agnieszka Stępień, Katarzyna Graczyk, Agata Leśniak‐Sobelga, Marta Hlawaty, Jakub Woźniak, Maryia Savitskaya, Katarzyna Holcman, Magdalena Kostkiewicz, Piotr Podolec, Paweł Rubiś   +12 more
wiley   +1 more source

Identification of tumor initiating cells and early marker genes in histologically normal colonic mucosa that lead to neoplastic transformation. [PDF]

Neoplasia
Jaiswal S, The S, Chang TS, Shi J, Wang TD.   +4 more
europepmc   +1 more source

Decoding epilepsy's molecular blueprint: Machine learning unravels transcriptomic subtypes and regulatory networks

Epilepsia, EarlyView.
Abstract Objective Drug‐resistant epilepsy (DRE) affects approximately one‐third of patients with epilepsy. The molecular heterogeneity underlying DRE remains poorly defined, largely due to limited access to resected brain tissue and substantial genetic diversity.
Yanping Weng, Yu Ma, Wanwan Hou, Haibo Li, Yuanfeng Zhou, Rui Zhao, Hao Li, Lian Chen, Yangyang Ma, Li Jin, Yi Wang, Yu An   +11 more
wiley   +1 more source

ODC1 Polyamine Metabolism Drives Prostate Cancer via AKT and Splicing. [PDF]

J Cell Mol Med
Ma J, Pan T, Sun S, Mutalifu M, Yang W, Niu Y, Chen P.   +6 more
europepmc   +1 more source

Sodium‐glucose cotransporter 2 inhibitors and the risk of late onset epilepsy: A real‐world cohort study

Epilepsia, EarlyView.
Abstract Objective Late onset epilepsy (LOE) is associated with substantial morbidity. Sodium‐glucose cotransporter 2 inhibitors (SGLT2i) may exert neuroprotective effects. This study evaluated the association between SGLT2i and risk of LOE among older adults with type 2 diabetes mellitus.
Bing‐Hua Lin, Hui‐Min Huang, Hui‐An Lin, Sheng‐Feng Lin   +3 more
wiley   +1 more source

DNA Methylation in Gastric Cancer and Preneoplastic Lesions: Emerging Insights and Future Directions. [PDF]

Cancers (Basel)
Ceccon C, Maddalena G, Angerilli V, Nappo F, Gasparello J, Sabbadin M, Toffolatti L, Bergamo F, Fassan M, Lonardi S.   +9 more
europepmc   +1 more source

c-Myb and C/EBPβ regulate OPN and other senescence-associated secretory phenotype factors [PDF]

, 2017
Alspach, Elise, Arthur, Laura L, Flanagan, Kevin C, Parajuli, Shankar, Pazolli, Ermira, Ren, Qihao, Stewart, Sheila A, Tapia, Roberto   +7 more
core   +2 more sources

Integrative genomic and spatial transcriptomic analysis elucidates the oligodendrocyte‐mediated etiology of epileptic cortical thinning

Epilepsia Open, EarlyView.
Abstract Objective Focal epilepsy is characterized by progressive cortical thinning, particularly within limbic structures; however, whether this atrophy reflects acquired seizure‐induced damage or shared genetic predisposition remains unresolved. Methods We integrated genome‐wide association study (GWAS) summary statistics from the ILAE Consortium ...
Dingyuan Zhang, Qianqian Zhang, Guangming Li, Lingting Yu, Yanling Ma, Xiaoli Hong, Yujie Kui, Shanshan Cai, Jianguang Sun, Zechao Zhu   +9 more
wiley   +1 more source

MicroRNA differential expression analysis in canine visceral hemangiosarcoma formalin-fixed, paraffin-embedded tissues. [PDF]

Front Vet Sci
Ribas LM, Muner K, Elshafie N, Rozanski E, Conrado FO, Dos Santos L, Dos Santos AP.   +6 more
europepmc   +1 more source

Spontaneous regression of equine sarcoids is an exceptional event

Equine Veterinary Journal, EarlyView.
Abstract Sarcoids are benign, yet locally aggressive skin tumours that commonly affect horses and other equid species. The lesions are induced by bovine papillomavirus types 1, 2, and probably 13 in conjunction with other factors including trauma and a genetic predisposition.
Sabine Brandt
wiley   +1 more source