Results 181 to 190 of about 638,559 (231)

Research progress on BTG2 in non‑tumor diseases (Review). [PDF]

Int J Mol Med
Li S, Liu X, Zhang Z, Yang L, Li Y, Hu Q.   +5 more
europepmc   +1 more source

Boron‐embedded multifunctional nanoplatform toward potential combined boron neutron capture therapy and immunomodulation in glioma

Smart Molecules, EarlyView.
A brain‐targeting multifunctional nanoplatform (DM&Ce6@COF‐Ang) was engineered by employing boron‐enriched APTES‐COF‐1 as both the therapeutic boron agent and the nanocarrier co‐delivery of DMXAA and Ce6. This nanoplatform achieved synergistic tumor‐specific boron delivery, real‐time pharmacokinetic monitoring, and immunomodulation.
Yiming Liu, Xuejian Wang, Bangjian Li, Kun Shao, Jianlong Su, Yang Wang, Lin Cheng, Zhihao Wu, JinRong Li, Guanyi Zhang, Xu Wang, Yuxuan Zhang, Yuanhao Liu, Guangzhe Li   +13 more
wiley   +1 more source

Deciphering the circadian signature in acute myeloid leukemia: NPAS2 downregulation as a master predictive feature. [PDF]

Blood Res
da Cunha LS, de Morais GP, Machado CB, de Sousa Oliveira D, Nogueira BMD, da Costa Machado AK, Farias IM, de Pinho Pessoa FMC, Ribeiro RM, de Alburquerque KMC, de Paula Gomes M, de Moraes Filho MO, de Moraes MEA, Moreira-Nunes CA.   +13 more
europepmc   +1 more source

PFOA Exposure Elicits Quantitative Lipidomic Changes in the Pancreas in a Mouse Model of Pancreatic Cancer

Environmental Toxicology, EarlyView.
ABSTRACT Pancreatic cancer is the fourth leading cause of cancer deaths in the US and predicted to rise to second by 2030. Several risk factors have been identified as potential contributors to pancreatic cancer development including lifestyle factors and long‐term exposure to occupational and environmental carcinogens.
Barbara A. Hocevar, Lisa M. Kamendulis
wiley   +1 more source

Mitochondrial Quality Regulation Genes as Prognostic Markers in Hepatocellular Carcinoma: Tumor Microenvironment, Therapeutic Response, and Drug Sensitivity Analysis. [PDF]

Drug Dev Res
Li B, Zeng L, He Z, Luo L, Luo Y, Yi X, Li Z, Zhu H, Li Y.   +8 more
europepmc   +1 more source

Deciphering diverse cell‐death patterns to predict the prognosis and potential therapy target of hepatocellular carcinoma patients

VIEW, EarlyView.
Abstract Ninety percent of all primary liver malignancies are hepatocellular carcinomas (HCC), making liver cancer the third most common cause of cancer‐associated mortality. Different patterns of programmed cell death (PCD) are crucial for the survival of tumors, and they might serve as a prognostic marker for HCC.
Lin Ding, Qian Li, Wenjing Yang, Te Liu, Tongtong Tian, Yu Liu, Chunyan Zhang, Baishen Pan, Beili Wang, Fan Wu, Wei Guo   +10 more
wiley   +1 more source

RNA-binding protein RBM47 in health and disease: molecular mechanisms, preclinical evidence, and translational challenges. [PDF]

Front Immunol
Huang S, Wang Q, Shen J, Wang X, Luo T, Yin J.   +5 more
europepmc   +1 more source

Angiogenesis‐associated immune genes as prognostic markers and predictors of immunotherapy response in pancreatic ductal adenocarcinoma

VIEW, EarlyView.
Pancreatic ductal adenocarcinoma exhibits marked angiogenic and immune heterogeneity. We identified 28 angiogenesis‐associated immune genes and developed a seven‐gene AIGScore model comprising FGF2, ADGRB3, MMP2, TYMP, VASH1, VEGFD, and ITGAV. A high AIGScore was associated with poor survival, an immunosuppressive tumor microenvironment, and reduced ...
Qing Chang, Qian Wang, Xiumei Jiang, Yongmei Yang, Ailin Qu   +4 more
wiley   +1 more source

Modulation of angiogenic transcription factor ERG via miR-6756 and miR-3190. [PDF]

PLoS One
Mumtaz S, Rashid MU, Khan SU, Malkani N.
europepmc   +1 more source