Deep learning‐assisted design of nanozyme for immune regulation
Overview of nanozyme‐based strategies for inflammatory bowel disease therapy, featuring metal‐based and non‐metallic nanozymes classified by structure, alongside multifunctional and engineered probiotic‐based nanozymes classified by function. Abstract Inflammatory bowel disease (IBD), with rising global incidence and disease burden, is a multifactorial
Ke Chen +3 more
wiley +1 more source
Unraveling the role of ChREBP in lung adenocarcinoma: Expression, regulatory networks, and potential functional impact. [PDF]
Ruangpracha A +8 more
europepmc +1 more source
ABSTRACT Background Risk factors for dermal leiomyosarcoma (dLMS) metastasis remain poorly defined because methodological constraints, small sample sizes, and short follow‐up have limited previous studies. Objectives To investigate risk factors for metastasis and local recurrence, and to propose a high‐ and low‐risk classification for dLMS. Methods All
Kiya Abebe +11 more
wiley +1 more source
Comprehensive profiling and molecular characterization of alternative splicing regulation in synaptic remodelling associated with neuropathic pain induced by chronic constrictive injury in a rat model. [PDF]
Zhou J, Jia Y, Song W, Zhang Y, Xia Z.
europepmc +1 more source
ABSTRACT Background Cutaneous squamous cell carcinoma (cSCC) is one of the most common nonmelanoma skin cancers, with increasing incidence globally. Beta genus human papillomaviruses (β‐HPVs), particularly in immunocompromised individuals, have been implicated in the development of cSCC. However, the strength of association between β‐HPV seropositivity
Shweh Fern Loo +3 more
wiley +1 more source
Identification and characterization of lncRNA-stemness-immune regulatory patterns. [PDF]
Qian Z +6 more
europepmc +1 more source
DERMACLEAR: AI‐Powered Insights Into Four Chronic Inflammatory Skin Diseases in Spain
Using an AI‐enhanced analysis of electronic health records from nearly 50,000 patients, the DERMACLEAR study provides real‐world insights into the prevalence, clinical complexity, comorbidities and treatment patterns of HS, CU, PsO and AD in Spain.
Ana Giménez‐Arnau +11 more
wiley +1 more source
MicroRNAs in cancer: biogenesis, biomarkers and therapeutic strategies. [PDF]
Rawat N, Babu N, Hussain A, Panwar AS.
europepmc +1 more source
The Regulatory Role and Mechanism of Myoferlin in Mitophagy During Papillary Thyroid Carcinogenesis
ABSTRACT Papillary thyroid carcinoma (PTC) is the most prevalent subtype of thyroid cancer; however, the regulatory mechanisms by which mitophagy influences its progression remain inadequately elucidated. This study sought to examine the role of myoferlin (MYOF) in mitophagy and its molecular basis during PTC development. Utilizing three paired PTC and
Wen‐Chao Lyu +6 more
wiley +1 more source

