Dynamic Multilevel Regulation of EGFR, KRAS, and MYC Oncogenes: Driving Cancer Cell Proliferation Through (Epi)Genetic and Post-Transcriptional/Translational Pathways. [PDF]
Seres M+5 more
europepmc +1 more source
We introduced the basic characterization and isolation methods of PEVs, reviewed the PEVs‐related articles pertaining to disease therapy and drug delivery system, and summarized the drug loading methods, storage techniques, and engineering modification strategies of the carrier, to establish a safer, more efficient and more affordable approach for ...
Jichun Yang+14 more
wiley +1 more source
Single-Cell RNA Sequencing on Formalin-Fixed and Paraffin-Embedded (FFPE) Tissue Identified Multi-Ciliary Cells in Breast Cancer. [PDF]
González-Martínez S+9 more
europepmc +1 more source
Illuminating Immunity: A Systematic Review of Immune Cell Autofluorescence
ABSTRACT Immunophenotyping provides valuable prognostic and diagnostic information, but is technically complex and expensive. The assessment of autofluorescence is label‐free and provides complex information on cell identity. However, research on its application to immunophenotyping has been heterogenous.
Aline Knab+4 more
wiley +1 more source
Lineage-Selective Dependencies in Pediatric Cancers. [PDF]
Ritter KE, Durbin AD.
europepmc +1 more source
New biomarkers are needed to make colorectal cancer (CRC) screening programs more efficient. Cancer cells secrete, in plasma, extracellular vesicles that contain proteins. Matrix Metalloproteinases 14 (MMP14) play a critical role in the initiation and progression of CRC.
Mickaël Barhoum+12 more
wiley +1 more source
Multi-omics analysis identifies OSGEPL1 as an oncogene in hepatocellular carcinoma. [PDF]
Mui S+7 more
europepmc +1 more source
Cytoplasmic HuR Expression Enhances Chemoresistance in Pleural Mesothelioma Through Increased Expression of CALB2, Promotion of the E2F Pathway, and Suppression of the p53 Pathway. [PDF]
Kirimura S+6 more
europepmc +1 more source
Exploring the mechanism of rosmarinic acid in the treatment of lung adenocarcinoma based on bioinformatics methods and experimental validation. [PDF]
Zhou C+12 more
europepmc +1 more source
A Review of Melanoma Subtypes: Genetic and Treatment Considerations
ABSTRACT Melanoma affects over one million people in the United States. This review explores genetic mutations and markers of all seven subtypes. Current treatment options and prognosis of each subtype are also discussed. For lentigo maligna, spitzoid, and nodular subtypes, BRAF was the most common mutation reported. For superficial spreading, TP53 was
Christina Druskovich+4 more
wiley +1 more source