Results 51 to 60 of about 7,007,953 (262)
Translational Oncology, 2014 BACKGROUND: Sessile serrated adenomas/polyps (SSA/P) are now recognised precursors of colorectal cancer (CRC) including cancers harbouring somatic BRAF (V600E) mutations.
Maria Caruso +11 more
doaj +1 more source
Balancing noise and plasticity in gene expression [PDF]
, 2011 Coupling the control of expression stochasticity (noise) with the capacity to expression change (plasticity) can constrain gene function and limit adaptation. Which factors contribute then to modulate this coupling?
Juan F. Poyatos, Djordje Bajic
core
Molecular Oncology, EarlyView.Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park +6 more
wiley +1 more source
Mice Transgenic for the Human Carcinoembryonic Antigen Gene Maintain Its Spatiotemporal Expression Pattern [PDF]
, 1994 The tumor marker carcinoembryonic antigen (CEA) is predominantly expressed in epithelial cells along the gastrointestinal tract and in a variety of adenocarcinomas.
Hirth, Antje +6 more
core +1 more source
Effect of STX5 on the metastasis of hepatocellular carcinoma and its mechanism [PDF]
精准医学杂志Objective To investigate the effect of STX5 on the metastasis of hepatocellular carcinoma (HCC) and its mechanism. Methods Clinical data were collected from 36 patients who were diagnosed with HCC in our hospital from January to December 2015, and the ...
GUO Tingting, ZHAO Ziyin, HE Mingyang, WU Tiansong, XU Bin, ZHANG Bin, WU Zehua, HAN Bing
doaj +1 more source
Regulation of gene expression by photosynthetic signals triggered through modified CO2 availability [PDF]
, 2006 Wormuth D, Baier M, Kandlbinder A, Scheibe R, Hartung W, Dietz K-J. Regulation of gene expression by photosynthetic signals triggered through modified CO2 availability. BMC PLANT BIOLOGY.
Scheibe Renate +17 more
core +1 more source
Cancer‐associated mutations in endometriosis reframe a benign disease through molecular oncology
Molecular Oncology, EarlyView.This review aims to comprehensively analyse cancer‐associated somatic mutations (CAMs) present in endometriotic lesions, emphasizing their biological roles, spatial distribution and implications for translational applications in medicine. By contextualizing a benign state within a genomic framework, this analysis seeks to establish its value as a ...
Clarissa Mujacic +15 more
wiley +1 more source
Regulatory effect of DNA methyltransferase 1 and DNA methyltransferase 3A on autophagy of human gastric cancer cells [PDF]
精准医学杂志Objective To investigate the regulatory effect of DNA methyltransferase 1 (DNMT1) and DNA methyltransferase 3A (DNMT3A) on autophagy of gastric cancer cells. Methods Western blot was used to measure the protein expression levels of DNMT1, DNMT3A, and DNA
LI Jing, KONG Wenyu, LIU Yu, LI Jing
doaj +1 more source
Cell Death Discovery, 2022 Eukaryotic translation initiation factor 4E binding protein 1 (EIF4EBP1) encodes the 4EBP1 protein, a negative regulator of mRNA translation and a substrate of the mechanistic target of rapamycin (mTOR), whose function and relevance in cancer is still ...
Laura Hauffe +7 more
doaj +1 more source
Molecular Oncology, EarlyView.Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley +1 more source