Results 221 to 230 of about 2,674,080 (353)

Molecular Mechanisms of Gene Expression Regulation in Response to Heat Stress in <i>Hemerocallis fulva</i>. [PDF]

Plants (Basel)
Chu B, Liu W, Li J, Zhang X, Li P.
europepmc   +1 more source

Mitochondrial tRNA-Derived Fragments and Their Contribution to Gene Expression Regulation. [PDF]

Front Physiol, 2021
Shaukat AN, Kaliatsi EG, Stamatopoulou V, Stathopoulos C.   +3 more
europepmc   +1 more source

Olaparib synergy screen reveals Exemestane induces replication stress in triple‐negative breast cancer

Molecular Oncology, EarlyView.
Screening 166 FDA‐approved anticancer drugs identifies the aromatase inhibitor Exemestane as a synergistic partner of PARP inhibitor Olaparib in BRCA‐proficient triple‐negative breast cancer. Exemestane induces ROS‐mediated replication stress, enhancing DNA damage and apoptosis alongside Olaparib.
Nur Aininie Yusoh, Liping Su, Suet Lin Chia, Xiaohe Tian, Haslina Ahmad, Martin R. Gill   +5 more
wiley   +1 more source

Mechanisms and therapeutic implications of gene expression regulation by circRNA-protein interactions in cancer. [PDF]

Commun Biol
Zhang N, Wang X, Li Y, Lu Y, Sheng C, Sun Y, Ma N, Jiao Y.   +7 more
europepmc   +1 more source

The Oncogenic PI3K-Induced Transcriptomic Landscape Reveals Key Functions in Splicing and Gene Expression Regulation. [PDF]

Cancer Res, 2022
Ladewig E, Michelini F, Jhaveri K, Castel P, Carmona J, Fairchild L, Zuniga AG, Arruabarrena-Aristorena A, Cocco E, Blawski R, Kittane S, Zhang Y, Sallaku M, Baldino L, Hristidis V, Chandarlapaty S, Abdel-Wahab O, Leslie C, Scaltriti M, Toska E.   +19 more
europepmc   +1 more source

Role of transcriptional and posttranscriptional regulation in expression of histone genes in Saccharomyces cerevisiae.

, 1987
Deborah E. Lycan, Mary Ann Osley, Lynna M. Hereford   +2 more
openalex   +1 more source

RKIP overexpression reduces lung adenocarcinoma aggressiveness and sensitizes cells to EGFR‐targeted therapies

Molecular Oncology, EarlyView.
RKIP, a metastasis suppressor protein, modulates key oncogenic pathways in lung adenocarcinoma. In silico analyses linked low RKIP expression to poor survival. Functional studies revealed RKIP overexpression reduces tumor aggressiveness and enhances sensitivity to EGFR‐targeted therapies, while its loss promotes resistance.
Ana Raquel‐Cunha, Joana Pinheiro, Rui F. Marques, Patrícia Fontão, Diana Cardoso‐Carneiro, Adriana Mendes, Izabela N. F. Gomes, Ana Carolina Laus, Renato J. da Silva‐Oliveira, Rui Manuel Reis, Olga Martinho   +10 more
wiley   +1 more source

Dynamic Chromatin Accessibility and Gene Expression Regulation During Maize Leaf Development. [PDF]

Genes (Basel)
Wang Y, Wang S, Wu Y, Cheng J, Wang H.
europepmc   +1 more source

Bioinformatics Applications to Reveal Molecular Mechanisms of Gene Expression Regulation in Model Organisms. [PDF]

Int J Mol Sci, 2021
Orlov YL, Tatarinova TV, Anashkina AA.
europepmc   +1 more source

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

Molecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou, Zhen Wang, Fei Yang, Xiao Han, Lei Li, Huadong Liu   +5 more
wiley   +1 more source