Results 111 to 120 of about 11,121,866 (385)

Autophagy in cancer and protein conformational disorders

FEBS Letters, EarlyView.
Autophagy plays a crucial role in numerous biological processes, including protein and organelle quality control, development, immunity, and metabolism. Hence, dysregulation or mutations in autophagy‐related genes have been implicated in a wide range of human diseases.
Sergio Attanasio
wiley   +1 more source

Genome-Wide Identification, Characterization, and Expression Profile of SWEETs Gene Family in Grapevine (Vitis vinifera L.)

Horticulturae
SWEET (Sugars Will Eventually Be Exported Transporter) proteins, identified recently as a novel class of sugar transporters, play pivotal roles in the transport and distribution of photosynthetic products in plants.
Linjing Zhong, Shuya Xu, Chenchen Song, Ning Zhao, Zhiqi Yang, Yanxiang Liu, Xiaoyue Cui, Jianxia Zhang, Zhi Li, Xiping Wang, Min Gao   +10 more
doaj   +1 more source

Counting and sampling gene family evolutionary histories in the duplication-loss and duplication-loss-transfer models [PDF]

arXiv, 2019
Given a set of species whose evolution is represented by a species tree, a gene family is a group of genes having evolved from a single ancestral gene. A gene family evolves along the branches of a species tree through various mechanisms, including - but not limited to - speciation, gene duplication, gene loss, horizontal gene transfer.
arxiv  

The classification of esterases: an important gene family involved in insecticide resistance--a review.

Memórias do Instituto Oswaldo Cruz, 2012
The use of chemical insecticides continues to play a major role in the control of disease vector populations, which is leading to the global dissemination of insecticide resistance.
Isabela Reis Montella, R. Schama, D. Valle   +2 more
semanticscholar   +1 more source

Gene duplication and inactivation in the HPRT gene family

Genomics, 2007
Hypoxanthine phosphoribosyltransferase (HPRT1) is a key enzyme in the purine salvage pathway, and mutations in HPRT1 cause Lesch-Nyhan disease. The studies described here utilized targeted comparative mapping and sequencing, in conjunction with database searches, to assemble a collection of 53 HPRT1 homologs from 28 vertebrates.
James W. Thomas, Nisc Comparative Sequencing Program, Robert T. Sullivan, Alaine C. Keebaugh   +3 more
openaire   +2 more sources

Brucella NyxA and NyxB dimerization enhances effector function during infection

FEBS Letters, EarlyView.
Brucella abortus thrives inside cells thanks to the translocation of effector proteins that fine‐tune cellular functions. NyxA and NyxB are two effectors that destabilize the nucleolar localization of their host target, SENP3. We show that the Nyx proteins directly interact with each other and that their dimerization is essential for their function ...
Lison Cancade‐Veyre, Arthur Louche, Francine C. A. Gérard, Laurent Terradot, Suzana P. Salcedo   +4 more
wiley   +1 more source

Genome-wide identification, characterization, and evolutionary analysis of the barley TALE gene family and its expression profiles in response to exogenous hormones

Frontiers in Plant Science
Three-amino-loop-extension (TALE) family belongs to the homeobox gene superfamily and occurs widely in plants, playing a crucial role in regulating their growth and development.
Tian-jiang Liao, Tian-jiang Liao, Tao Huang, Hui-yan Xiong, Jie-cuo Duo, Jie-cuo Duo, Jian-zhi Ma, Ming-yang Du, Rui-jun Duan, Rui-jun Duan   +9 more
doaj   +1 more source

Genome-Wide Identification of Chalcone Reductase Gene Family in Soybean: Insight into Root-Specific GmCHRs and Phytophthora sojae Resistance

Frontiers in Plant Science, 2017
Soybean (Glycine max [L.] Merr) is one of the main grain legumes worldwide. Soybean farmers lose billions of dollars’ worth of yield annually due to root and stem rot disease caused by the oomycete Phytophthora sojae.
Caroline J. Sepiol, Caroline J. Sepiol, Jaeju Yu, Sangeeta Dhaubhadel, Sangeeta Dhaubhadel   +4 more
doaj   +1 more source

Lateral Gene Transfer, Rearrangement and Reconciliation [PDF]

arXiv, 2013
Background. Models of ancestral gene order reconstruction have progressively integrated different evolutionary patterns and processes such as unequal gene content, gene duplications, and implicitly sequence evolution via reconciled gene trees. In unicellular organisms, these models have so far ignored lateral gene transfer, even though it can have an
arxiv  

The polyphenol oxidase gene family in land plants: Lineage-specific duplication and expansion

BMC Genomics, 2012
BackgroundPlant polyphenol oxidases (PPOs) are enzymes that typically use molecular oxygen to oxidize ortho-diphenols to ortho-quinones. These commonly cause browning reactions following tissue damage, and may be important in plant defense.
Lan T. Tran, J. Taylor, C. Constabel
semanticscholar   +1 more source