Results 171 to 180 of about 11,790,132 (329)

Frequency and Types of Point Mutation at the 12th Codon of the c‐Ki‐ras Gene Found in Pancreatic Cancers from Japanese Patients [PDF]

, 1989
Mariko Mariyama, Kiyozo Kishi, Kozo Nakamura, Hiroshi Obata, Susumu Nishimura   +4 more
openalex   +1 more source

Loss of primary cilia promotes EphA2‐mediated endothelial‐to‐mesenchymal transition in the ovarian tumor microenvironment

Molecular Oncology, EarlyView.
Loss of primary cilia in endothelial cells promotes EndMT and vascular abnormalities in the ovarian tumor microenvironment through EphA2 activation. Using human samples, in vitro models, and endothelial‐specific Kif3a‐knockout mice, we show that primary cilia loss drives the acquisition of cancer‐associated fibroblast‐like phenotypes, thereby ...
Jin Gu Cho, Yubin Hah, Eunsik Yun, Hye In Ka, Aram Lee, Sora Han, Dawn Lee, Sung Wook Kim, Jong Hoon Park, Byung Su Kwon, Young Yang, Jongmin Kim   +11 more
wiley   +1 more source

Differential A1/A2 β-casein (<i>CSN2</i>) gene-derived allelic and genotypic frequencies across Ecuadorian exotic dairy cattle breeds. [PDF]

Front Vet Sci
Cartuche-Macas LF, Navarrete-Mera JF, Gutiérrez-Reinoso MA, García-Herreros M.   +3 more
europepmc   +1 more source

Gene frequency and partial protein characterization of an allelic variant of mannan binding protein associated with low serum concentrations

Clinical and Experimental Immunology, 1992
P. Garred, Steffen Thiel, H. Madsen, L. Ryder, J. C. Jensenius, A. Svejgaard   +5 more
semanticscholar   +1 more source

The Frequency of CYP2C19&ast;2 Gene Polymorphisms in Burkina Faso Patients Treated with Clopidogrel

The Application of Clinical Genetics
Yves Donald Kagambèga,1,2,&ast; Abdoul Karim Ouattara,1,2,&ast; Teega-Wendé Clarisse Ouédraogo,2,3 Lassina Traoré,2,3 Nobila Valentin Yaméogo,4 Jacques Simpore1,2 1Biological Sciences, Université Norbert Zongo/ Centre Universitaire de Manga ...
Kagambèga YD, Ouattara AK, Ouédraogo TWC, Traoré L, Yaméogo NV, Simpore J   +5 more
doaj  

High-frequency meiotic gene conversion between repeated genes on nonhomologous chromosomes in yeast. [PDF]

, 1985
Sue Jinks-Robertson, T D Petes
openalex   +1 more source

Genomics‐led approach to drug testing in models of undifferentiated pleomorphic sarcoma

Molecular Oncology, EarlyView.
GA text Genomic data from undifferentiated pleomorphic sarcoma patients and preclinical models were used to inform a targeted drug screen. Selected compounds were tested in 2D and 3D cultures of UPS cell lines. A combination of trametinib and infigratinib was synergistic in the majority of UPS cell lines tested, which was further confirmed in an ex ...
Piotr J. Manasterski, Molly R. Danks, John P. Thomson, Morwenna Muir, Martin Lee, John C. Dawson, Ana T. Amaral, Juan Diaz‐Martin, David S. Moura, Javier Martin‐Broto, Ali Alsaadi, Donald M. Salter, Ailsa J. Oswald, Graeme Grimes, Larry Hayward, Ted R. Hupp, Karen Sisley, Paul H. Huang, Neil O. Carragher, Valerie G. Brunton   +19 more
wiley   +1 more source

Genetic foundations of interindividual neurophysiological variability. [PDF]

Sci Adv
da Silva Castanheira J, Poli J, Hansen JY, Misic B, Baillet S.   +4 more
europepmc   +1 more source

High frequency of clonal immunoglobulin or T cell receptor gene rearrangements in acute myelogenous leukemia expressing terminal deoxyribonucleotidyltransferase. [PDF]

, 1987
Stephanie Seremetis, Pier Giuseppe Pelicci, Antonio Tabilio, A Ubriaco, F Grignani, Janet Cuttner, Robert Winchester, Dan Knowles, Riccardo Dalla‐Favera   +8 more
openalex   +1 more source

The subcellular distribution of phosphorylated Y‐box‐binding protein‐1 at S102 in colorectal cancer patients, stratified by KRAS mutational status and clinicopathological features

Molecular Oncology, EarlyView.
This study identifies nuclear YB‐1 S102 phosphorylation as a marker associated with KRAS and FBXW7 mutations in colorectal cancer. Mutated KRAS correlates specifically with nuclear, not cytoplasmic, S102 YB‐1. These findings provide the first ex vivo evidence of this link in CRC and suggest future studies should assess the prognostic and therapeutic ...
Konstanze Lettau, Stephan Forchhammer, Birgit Fehrenbacher, Lejla Mahmutovic, Marcus Scharpf, Gunnar Blumenstock, Martin Schaller, Irina Bonzheim, Shayan Khozooei, Mahmoud Toulany   +9 more
wiley   +1 more source