Results 181 to 190 of about 13,063,295 (390)

Incidence, prevalence, and gene frequency studies of chronic childhood spinal muscular atrophy.

Journal of Medical Genetics, 1978
J. Pearn
semanticscholar   +1 more source

Strength through diversity: how cancers thrive when clones cooperate

Molecular Oncology, EarlyView.
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken, Maartje Witsen, Emile E. Voest, Krijn K. Dijkstra   +3 more
wiley   +1 more source

THE VARIANCE OF THE NUMBER OF LOCI HAVING A GIVEN GENE FREQUENCY [PDF]

, 1973
Takeo Maruyama
openalex   +1 more source

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

Molecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto, Louise Raunkilde, Jan Lindebjerg, Mads Malik Aagaard, Christina Therkildsen, Jakob Kleif, Lars Henrik Jensen, Torben Frøstrup Hansen, Rikke Fredslund Andersen   +8 more
wiley   +1 more source

gwSPADE: gene frequency-weighted reference-free deconvolution in spatial transcriptomics. [PDF]

Nucleic Acids Res
Xie A, Steele NG, Cui Y.
europepmc   +1 more source

SPECTRUM AND FREQUENCY OF NK CELL RECEPTOR GENES AMONG CYSTIC FIBROSIS PATIENTS

, 2020
D. V. Zastavna, K. O. Sosnina, O. I. Terpyliak, Halyna Makukh, B. I. Tretiak, L. Bober, Miroslav Tyrka   +6 more
openalex   +2 more sources

Frequency of Mutations of the Cystic Fibrosis Transmembrane Regulator Gene in a Cohort of Consecutive Patient Candidates for Assisted Reproductive Techniques [PDF]

, 2012
Mauro Rongioletti, Fabrizio Papa, MariaBernardetta Majolini, Cinzia Vaccarella, Francesca Neri, Ilaria Simonelli, Valentina Mazzucchi, Giancarlo Maria Liumbruno   +7 more
openalex   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Gene frequency and partial protein characterization of an allelic variant of mannan binding protein associated with low serum concentrations

Clinical and Experimental Immunology, 1992
P. Garred, Steffen Thiel, H. Madsen, L. Ryder, J. C. Jensenius, A. Svejgaard   +5 more
semanticscholar   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source